Role of exosomes in transferring chemoresistance through modulation of cancer glycolytic cell metabolism.
暂无分享,去创建一个
E. Giovannetti | G. Peters | L. Morelli | R. Smolenski | Annalisa Comandatore | M. Vahabi | A. Comandatore | Marika A Franczak | R. Smoleński | Marika A Frańczak
[1] J. Kopecka,et al. The role of Extracellular Vesicles in glycolytic and lipid metabolic reprogramming of cancer cells: Consequences for drug resistance. , 2023, Cytokine & growth factor reviews.
[2] Kyoung Song,et al. Modulating Glycolysis to Improve Cancer Therapy , 2023, International journal of molecular sciences.
[3] Cheng Xiao,et al. Exosomes-mediated tumor metastasis through reshaping tumor microenvironment and distant niche. , 2022, Journal of controlled release : official journal of the Controlled Release Society.
[4] E. Giovannetti,et al. Lactate Dehydrogenase and its clinical significance in pancreatic and thoracic cancers. , 2022, Seminars in cancer biology.
[5] Yujuan Huang,et al. Exosome-mediated remodeling of the tumor microenvironment: From local to distant intercellular communication. , 2022, Cancer letters.
[6] W. Chen,et al. Renal cell carcinoma-derived exosomes deliver lncARSR to induce macrophage polarization and promote tumor progression via STAT3 pathway , 2022, International journal of biological sciences.
[7] Z. Gil,et al. The Role of Extracellular Vesicles in Metabolic Reprogramming of the Tumor Microenvironment , 2022, Cells.
[8] E. Giovannetti,et al. The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells. , 2022, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[9] E. Giovannetti,et al. Potential Role of Exosomes in the Chemoresistance to Gemcitabine and Nab-Paclitaxel in Pancreatic Cancer , 2022, Diagnostics.
[10] M. Ye,et al. Exosome-delivered circular RNA DLGAP4 induces chemoresistance via miR-143-HK2 axis in neuroblastoma. , 2022, Cancer biomarkers : section A of Disease markers.
[11] Xiaoyun He,et al. Emerging Role of Cancer-Associated Fibroblasts-Derived Exosomes in Tumorigenesis , 2022, Frontiers in Immunology.
[12] G. Di Stefano,et al. Lactate Upregulates the Expression of DNA Repair Genes, Causing Intrinsic Resistance of Cancer Cells to Cisplatin , 2021, Pathology & Oncology Research.
[13] K. Alfarouk,et al. Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches , 2021, Cancers.
[14] A. Gonçalves,et al. Impact of cancer metabolism on therapy resistance - Clinical implications. , 2021, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[15] M. Rafat,et al. Extracellular vesicles: mediators of intercellular communication in tissue injury and disease , 2021, Cell communication and signaling : CCS.
[16] I. Kerkis,et al. Exosomes in the Tumor Microenvironment: From Biology to Clinical Applications , 2021, Cells.
[17] Yue Li,et al. Hypoxia and the Tumor Microenvironment , 2021, Technology in cancer research & treatment.
[18] B. Zhivotovsky,et al. Receptor-Mediated Mitophagy Rescues Cancer Cells under Hypoxic Conditions , 2021, Cancers.
[19] Fan Wang,et al. Hypoxic exosomal HIF-1α-stabilizing circZNF91 promotes chemoresistance of normoxic pancreatic cancer cells via enhancing glycolysis , 2021, Oncogene.
[20] Xiaomei Liu,et al. Exosomal miR‐21‐5p derived from cisplatin‐resistant SKOV3 ovarian cancer cells promotes glycolysis and inhibits chemosensitivity of its progenitor SKOV3 cells by targeting PDHA1 , 2021, Cell biology international.
[21] V. LeBleu,et al. Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer , 2021, Life Science Alliance.
[22] G. Rice,et al. Extracellular Vesicle Transmission of Chemoresistance to Ovarian Cancer Cells Is Associated with Hypoxia-Induced Expression of Glycolytic Pathway Proteins, and Prediction of Epithelial Ovarian Cancer Disease Recurrence , 2021, Cancers.
[23] L. Ming,et al. Overcoming Chemoresistance via Extracellular Vesicle Inhibition , 2021, Frontiers in Molecular Biosciences.
[24] Hang Yu,et al. Exosomes Derived From Macrophages Enhance Aerobic Glycolysis and Chemoresistance in Lung Cancer by Stabilizing c-Myc via the Inhibition of NEDD4L , 2021, Frontiers in Cell and Developmental Biology.
[25] M. V. Vander Heiden,et al. The Metabolic Landscape of RAS-Driven Cancers from biology to therapy , 2021, Nature Cancer.
[26] Min Su,et al. The cancer metabolic reprogramming and immune response , 2021, Molecular cancer.
[27] Ping Zhang,et al. CAFs-Derived Exosomal miRNA-130a Confers Cisplatin Resistance of NSCLC Cells Through PUM2-Dependent Packaging , 2021, International journal of nanomedicine.
[28] Jian Zhao,et al. Cisplatin-resistant NSCLC cells induced by hypoxia transmit resistance to sensitive cells through exosomal PKM2 , 2021, Theranostics.
[29] M. Donadelli,et al. Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance , 2020, Cells.
[30] E. Giovannetti,et al. “Open Sesame?”: Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer , 2020, Cancers.
[31] B. Rolando,et al. MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells. , 2020, Biochimica et biophysica acta. Molecular cell research.
[32] Lei Zhan,et al. Tumor-Derived Exosome-Educated Hepatic Stellate Cells Regulate Lactate Metabolism of Hypoxic Colorectal Tumor Cells via the IL-6/STAT3 Pathway to Confer Drug Resistance , 2020, OncoTargets and therapy.
[33] W. Olejarz,et al. Exosomes in Angiogenesis and Anti-angiogenic Therapy in Cancers , 2020, International journal of molecular sciences.
[34] Z. Heger,et al. Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition , 2020, International journal of molecular sciences.
[35] L. Ye,et al. MiR-210 in exosomes derived from CAFs promotes non-small cell lung cancer migration and invasion through PTEN/PI3K/AKT pathway. , 2020, Cellular signalling.
[36] R. Kalluri,et al. Exosomes as a Multicomponent Biomarker Platform in Cancer. , 2020, Trends in cancer.
[37] Yuanting Gu,et al. Cancer-associated fibroblasts-derived exosomes suppresses immune cell function in breast cancer via miR-92/PD-L1 pathway , 2020 .
[38] R. Savai,et al. Tumor-derived exosomes in the regulation of macrophage polarization , 2020, Inflammation Research.
[39] M. Montopoli,et al. Metabolic Plasticity in Chemotherapy Resistance , 2020, Frontiers in Oncology.
[40] Ç. Biray Avcı,et al. Crucial Players in Glycolysis: Cancer Progress. , 2020, Gene.
[41] A. Mantovani,et al. Diversity, Mechanisms, and Significance of Macrophage Plasticity. , 2020, Annual review of pathology.
[42] Y. Ba,et al. Exosome‐delivered circRNA promotes glycolysis to induce chemoresistance through the miR‐122‐PKM2 axis in colorectal cancer , 2020, Molecular oncology.
[43] L. O’Driscoll,et al. Inhibiting extracellular vesicles formation and release: a review of EV inhibitors , 2019, Journal of extracellular vesicles.
[44] L. Freitag,et al. Inhibition of kras-derived exosomes downregulates immunosuppressive BACH2/GATA-3 expression via RIP-3 dependent necroptosis and miR-146/miR-210 modulation. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[45] Samar H. Ibrahim,et al. Integrin β1-enriched Extracellular Vesicles Mediate Monocyte Adhesion and Promote Liver Inflammation in Murine NASH. , 2019, Journal of hepatology.
[46] E. Giovannetti,et al. New avenues in pancreatic cancer: exploiting microRNAs as predictive biomarkers and new approaches to target aberrant metabolism , 2019, Expert review of clinical pharmacology.
[47] Heshui Wu,et al. Exosomes derived from cancer stem cells of gemcitabine-resistant pancreatic cancer cells enhance drug resistance by delivering miR-210 , 2019, Cellular Oncology.
[48] M. Xie,et al. Role of hypoxia in cancer therapy by regulating the tumor microenvironment , 2019, Molecular Cancer.
[49] F. Dilworth,et al. The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance , 2019, Oncogene.
[50] M. Osaki,et al. Exosomes and Their Role in Cancer Progression. , 2019, Yonago acta medica.
[51] D. Banerjee,et al. Lactate Dehydrogenases as Metabolic Links between Tumor and Stroma in the Tumor Microenvironment , 2019, Cancers.
[52] E. Giovannetti,et al. Pharmacogenetics of treatments for pancreatic cancer , 2019, Expert opinion on drug metabolism & toxicology.
[53] F. Su,et al. Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells , 2019, Nature Cell Biology.
[54] Jianjun Chen,et al. Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin , 2019, Molecular oncology.
[55] C. Théry,et al. Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication , 2019, Nature Cell Biology.
[56] F. Zhou,et al. Prognostic Significance of Serum Lactic Acid, Lactate Dehydrogenase, and Albumin Levels in Patients with Metastatic Colorectal Cancer , 2018, BioMed research international.
[57] M. Donadelli,et al. Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer , 2018, Journal of Experimental & Clinical Cancer Research.
[58] Jingru Liu,et al. Exosomes derived from acute myeloid leukemia cells promote chemoresistance by enhancing glycolysis‐mediated vascular remodeling , 2018, Journal of cellular physiology.
[59] C. Berkers,et al. The Influence of Metabolism on Drug Response in Cancer , 2018, Front. Oncol..
[60] M. Simpson,et al. The role of cellular reactive oxygen species in cancer chemotherapy , 2018, Journal of experimental & clinical cancer research : CR.
[61] X. Wan,et al. Loss of exosomal miR‐148b from cancer‐associated fibroblasts promotes endometrial cancer cell invasion and cancer metastasis , 2018, Journal of cellular physiology.
[62] A. Möller,et al. Breast Cancer-Derived Exosomes Alter Macrophage Polarization via gp130/STAT3 Signaling , 2018, Front. Immunol..
[63] S. Caja,et al. Exosome-Based Cell-Cell Communication in the Tumor Microenvironment , 2018, Front. Cell Dev. Biol..
[64] Hongyang Wang,et al. Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer , 2018, Nature Communications.
[65] J. Dai,et al. LDHA promotes tumor metastasis by facilitating epithelial‑mesenchymal transition in renal cell carcinoma. , 2017, Molecular medicine reports.
[66] Fengming Yang,et al. Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts , 2017, Molecular Cancer.
[67] M. Lulli,et al. The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction , 2017, Stem cells international.
[68] E. Giovannetti,et al. Drug resistance in pancreatic cancer: Impact of altered energy metabolism. , 2017, Critical reviews in oncology/hematology.
[69] Raghu Kalluri,et al. Exosomes Facilitate Therapeutic Targeting of Oncogenic Kras in Pancreatic Cancer , 2017, Nature.
[70] M. Henry,et al. Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles , 2017, Scientific Reports.
[71] Y. Takeda,et al. MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma , 2017, Scientific Reports.
[72] Mohammad Aslam Khan,et al. Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK , 2017, British Journal of Cancer.
[73] J. Kopecka,et al. P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors , 2016, Oncotarget.
[74] Yuan Yang,et al. MicroRNA-210 promotes cancer angiogenesis by targeting fibroblast growth factor receptor-like 1 in hepatocellular carcinoma. , 2016, Oncology reports.
[75] Qing‐Yu He,et al. Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages , 2016, Oncotarget.
[76] R. Hill,et al. CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS , 2016, Oncogene.
[77] Venkatareddy Nadithe,et al. Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges , 2016, Acta pharmaceutica Sinica. B.
[78] Shivakumar Keerthikumar,et al. ExoCarta: A Web-Based Compendium of Exosomal Cargo. , 2016, Journal of molecular biology.
[79] R. Soong,et al. The Warburg effect and drug resistance , 2016, British journal of pharmacology.
[80] M. Hasan,et al. Cancer Metabolism and Drug Resistance , 2015, Metabolites.
[81] B. Zetter,et al. The Contribution of Angiogenesis to the Process of Metastasis. , 2015, Cancer journal.
[82] Michael A. Hollingsworth,et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver , 2015, Nature Cell Biology.
[83] Salma Khan,et al. Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase , 2015, OncoTargets and therapy.
[84] S. Raimondo,et al. Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism , 2015, Cell Communication and Signaling.
[85] C. Porta,et al. The role of the cell–cell interactions in cancer progression , 2015, Journal of cellular and molecular medicine.
[86] E. Gazzano,et al. Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma , 2014, Oncotarget.
[87] D. Mukhopadhyay,et al. GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways , 2014, PloS one.
[88] F. Bianchini,et al. The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy , 2014, Cell cycle.
[89] E. Giovannetti,et al. Molecular Mechanisms Underlying the Role of MicroRNAs in the Chemoresistance of Pancreatic Cancer , 2014, BioMed research international.
[90] Pieter Vader,et al. Extracellular vesicles: emerging targets for cancer therapy. , 2014, Trends in molecular medicine.
[91] S. McKeown,et al. Defining normoxia, physoxia and hypoxia in tumours-implications for treatment response. , 2014, The British journal of radiology.
[92] N. Wall,et al. Enhancement of Gemcitabine sensitivity in pancreatic adenocarcinoma by novel exosome-mediated delivery of the Survivin-T34A mutant , 2014, Journal of extracellular vesicles.
[93] Triantafyllos Stylianopoulos,et al. Combining two strategies to improve perfusion and drug delivery in solid tumors , 2013, Proceedings of the National Academy of Sciences.
[94] Y. Wang,et al. MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain , 2013, Gene Therapy.
[95] W. Ding,et al. Intercellular Communication by Exosome-Derived microRNAs in Cancer , 2013, International journal of molecular sciences.
[96] Wenchuan Wu,et al. Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells , 2013, Tumor Biology.
[97] E. Giovannetti,et al. Molecular targets of gemcitabine action: rationale for development of novel drugs and drug combinations. , 2012, Current pharmaceutical design.
[98] Gema Moreno-Bueno,et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET , 2012, Nature Medicine.
[99] A. Sapino,et al. HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast , 2012, BMC Cancer.
[100] F. Khuri,et al. Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD+ Redox Homeostasis in Cancer Cells , 2011, Molecular and Cellular Biology.
[101] P. Oefner,et al. Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. , 2009, Neuro-oncology.
[102] Fabio Martelli,et al. MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3* , 2008, Journal of Biological Chemistry.
[103] J. Lötvall,et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.
[104] G. Peters,et al. Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines , 2003, British Journal of Cancer.
[105] S. Kanwal,et al. Cancer Chemoresistance; Recent Challenges and Future Considerations. , 2023, Cancer treatment and research.
[106] Di Liu,et al. miR-449a Suppresses LDHA-Mediated Glycolysis to Enhance the Sensitivity of Non-Small Cell Lung Cancer Cells to Ionizing Radiation. , 2018, Oncology research.
[107] W. Rathmell,et al. Metabolic Alterations in Cancer and Their Potential as Therapeutic Targets. , 2017, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
[108] M. Miyazaki,et al. Cobalt Chloride Induces Expression and Function of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Renal Proximal Tubular Epithelial Cell Line HK-2. , 2017, Biological & pharmaceutical bulletin.
[109] T. Whiteside. Tumor-Derived Exosomes and Their Role in Cancer Progression. , 2016, Advances in clinical chemistry.
[110] John R. Mackey,et al. Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial. , 2014, Journal of the National Cancer Institute.
[111] Adam P Dicker,et al. Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer. , 2009, Gastroenterology.