Causes of Late Revision Surgery after Bone Cement Augmentation in Osteoporotic Vertebral Compression Fractures

Study Design A retrospective study. Purpose To elucidate the causes of late revision following bone cement augmentation for osteoporotic vertebral compression fractures (OVCFs). Overview of Literature Percutaneous vertebroplasty (PVP) or kyphoplasty (KP) is thought to be effective for the treatment of OVCFs. Many complications related to PVP or KP have been reported. However, there is a paucity of reports regarding the causes of late revision surgery after failed PVP or KP. Methods Twenty six patients who developed unremitted back pain and/or progressive neurological deficit after a symptom-free period since treatment with PVP or KP were enrolled. All patients underwent cement removal and anterior reconstruction. Among the 26 patients, 22 patients underwent anterior interbody fusion combined with posterior instrumentation; 4 patients underwent anterior reconstruction only. The causes of revision surgery were assessed. Clinical results were assessed using a visual analogue scale (VAS) and Oswestry Disability Index (ODI). The complications were analyzed. Results The average time to revision surgery was 18.9±14.6 months (range, 3-78 months). The causes of late revision surgery included 6 late infections, 8 progressive kyphoses, 10 proximal fractures after instrumented lumbar fusions, and 2 late neurological involvement. During the mean follow-up period of 13.5±7.8 months, pre-revision mean VAS (8.5±0.9) and ODI (81.2±12.5) were improved to 4.2±1.4 and 54.8±17.6, respectively. Five patients (19%) had serious complications after revision surgery. Conclusions This study presents complications of PVP or KP in the treatment of OVCFs although PVP or KP can be an effective treatment strategy for OVCF when applied in highly selected patients.

[1]  N. Hasan,et al.  Sensitivity, Specificity and Accuracy of Magnetic Resonance Imaging for Differentiating Vertebral Compression Fractures Caused by Malignancy, Osteoporosis, and Infections , 2011, Journal of orthopaedic surgery.

[2]  K. Sairyo,et al.  Anterior thoracolumbar reconstruction surgery for late collapse following vertebroplasty: report of three cases. , 2011, The journal of medical investigation : JMI.

[3]  K. Ha,et al.  Revision Surgery after Vertebroplasty or Kyphoplasty , 2010, Clinics in orthopedic surgery.

[4]  Young-Yul Kim,et al.  Recompression of vertebral body after balloon kyphoplasty for osteoporotic vertebral compression fracture , 2010, European Spine Journal.

[5]  Tom Stanley,et al.  Percutaneous Treatment of Vertebral Compression Fractures: A Meta-analysis of Complications , 2009, Spine.

[6]  K. Ha,et al.  Surgical treatment for delayed pyogenic spondylitis after percutaneous vertebroplasty and kyphoplasty. Report of 4 cases. , 2008, Journal of neurosurgery. Spine.

[7]  D. Yoon,et al.  Progressive collapse of PMMA-augmented vertebra: a report of three cases. , 2008, Zentralblatt für Neurochirurgie.

[8]  K. Ha,et al.  Percutaneous vertebroplasty for vertebral compression fractures with and without intravertebral clefts. , 2006, The Journal of bone and joint surgery. British volume.

[9]  S. T. Yoon,et al.  Kyphoplasty for Salvage of a Failed Vertebroplasty in Osteoporotic Vertebral Compression Fractures: Case Report and Surgical Technique , 2005, Journal of spinal disorders & techniques.

[10]  Yeung-Jen Chen,et al.  Serious Pyogenic Spondylitis Following Vertebroplasty—A Case Report , 2004, Spine.

[11]  T. Faciszewski,et al.  Reporting Height Restoration in Vertebral Compression Fractures , 2003, Spine.

[12]  A. Mehbod,et al.  Vertebroplasty for osteoporotic spine fracture: prevention and treatment , 2003, European Spine Journal.

[13]  D. Kallmes,et al.  The therapeutic benefit of repeat percutaneous vertebroplasty at previously treated vertebral levels. , 2002, AJNR. American journal of neuroradiology.

[14]  T. Maus,et al.  Intravertebral clefts opacified during vertebroplasty: pathogenesis, technical implications, and prognostic significance. , 2002, AJNR. American journal of neuroradiology.

[15]  R. Rossi,et al.  Percutaneous vertebroplasty: long-term clinical and radiological outcome , 2002, Neuroradiology.

[16]  B. Lee,et al.  Paraplegia as a Complication of Percutaneous Vertebroplasty With Polymethylmethacrylate: A Case Report , 2002, Spine.

[17]  David F Kallmes,et al.  Vertebroplasty in the mid- and upper thoracic spine. , 2002, AJNR. American journal of neuroradiology.

[18]  I. Tsou,et al.  Differentiation of malignant vertebral collapse from osteoporotic and other benign causes using magnetic resonance imaging. , 2002, Annals of the Academy of Medicine, Singapore.

[19]  K. Harrington,et al.  Major neurological complications following percutaneous vertebroplasty with polymethylmethacrylate : a case report. , 2001, The Journal of bone and joint surgery. American volume.

[20]  F. Grados,et al.  Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. , 2009, Rheumatology.

[21]  J. Barr,et al.  Percutaneous Vertebroplasty for Pain Relief and Spinal Stabilization , 2000, Spine.

[22]  M Deimling,et al.  Diffusion-weighted MR imaging of bone marrow: differentiation of benign versus pathologic compression fractures. , 1998, Radiology.

[23]  D F Kallmes,et al.  Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. , 1997, AJNR. American journal of neuroradiology.

[24]  J. Chiras,et al.  [Percutaneous vertebral surgery. Technics and indications]. , 1997, Journal of neuroradiology. Journal de neuroradiologie.

[25]  D. C. Henckel,et al.  Case report. , 1995, Journal.

[26]  H. Deramond,et al.  [Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty]. , 1987, Neuro-Chirurgie.