Fewer Hospitalizations for Acute Cardiovascular Conditions During the COVID-19 Pandemic

Background Although patients with cardiovascular disease face excess risks of severe illness with coronavirus disease-2019 (COVID-19), there may be indirect consequences of the pandemic on this high-risk patient segment. Objectives This study sought to examine longitudinal trends in hospitalizations for acute cardiovascular conditions across a tertiary care health system. Methods Acute cardiovascular hospitalizations were tracked between January 1, 2019, and March 31, 2020. Daily hospitalization rates were estimated using negative binomial models. Temporal trends in hospitalization rates were compared across the first 3 months of 2020, with the first 3 months of 2019 as a reference. Results From January 1, 2019, to March 31, 2020, 6,083 patients experienced 7,187 hospitalizations for primary acute cardiovascular reasons. There were 43.4% (95% confidence interval [CI]: 27.4% to 56.0%) fewer estimated daily hospitalizations in March 2020 compared with March 2019 (p < 0.001). The daily rate of hospitalizations did not change throughout 2019 (–0.01% per day [95% CI: –0.04% to +0.02%]; p = 0.50), January 2020 (–0.5% per day [95% CI: –1.6% to +0.5%]; p = 0.31), or February 2020 (+0.7% per day [95% CI: –0.6% to +2.0%]; p = 0.27). There was significant daily decline in hospitalizations in March 2020 (–5.9% per day [95% CI: –7.6% to –4.3%]; p < 0.001). Length of stay was shorter (4.8 days [25th to 75th percentiles: 2.4 to 8.3 days] vs. 6.0 days [25th to 75th percentiles: 3.1 to 9.6 days]; p = 0.003) and in-hospital mortality was not significantly different (6.2% vs. 4.4%; p = 0.30) in March 2020 compared with March 2019. Conclusions During the first phase of the COVID-19 pandemic, there was a marked decline in acute cardiovascular hospitalizations, and patients who were admitted had shorter lengths of stay. These data substantiate concerns that acute care of cardiovascular conditions may be delayed, deferred, or abbreviated during the COVID-19 pandemic.

[1]  Deepak L. Bhatt,et al.  COVID-19: An Unintended Force for Medical Revolution? , 2020, The Journal of invasive cardiology.

[2]  Catherine Klersy,et al.  Out-of-Hospital Cardiac Arrest during the Covid-19 Outbreak in Italy , 2020, The New England journal of medicine.

[3]  K. Yuen,et al.  Clinical Characteristics of Coronavirus Disease 2019 in China , 2020, The New England journal of medicine.

[4]  F. Fedele,et al.  Reduced Rate of Hospital Admissions for ACS during Covid-19 Outbreak in Northern Italy , 2020, The New England journal of medicine.

[5]  C. Yancy,et al.  COVID-19 and African Americans. , 2020, JAMA.

[6]  A. E. Tondas,et al.  A time‐to‐event analysis on air pollutants with the risk of cardiovascular disease and mortality: A systematic review and meta‐analysis of 84 cohort studies , 2020, Journal of evidence-based medicine.

[7]  A. Ceriello,et al.  Evidence for an Independent and Cumulative Effect of Postprandial Hypertriglyceridemia and Hyperglycemia on Endothelial Dysfunction and Oxidative Stress Generation: Effects of Short- and Long-Term Simvastatin Treatment , 2002, Circulation.

[8]  A. Bauer,et al.  Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage , 2020, European heart journal.

[9]  D. Grabowski,et al.  Postacute Care Preparedness for COVID-19: Thinking Ahead. , 2020, JAMA.

[10]  C. Schmidt,et al.  Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States During COVID-19 Pandemic , 2020, Journal of the American College of Cardiology.

[11]  Á. Cequier,et al.  Impacto de la pandemia de COVID-19 sobre la actividad asistencial en cardiología intervencionista en España , 2020, REC: interventional cardiology.

[12]  Binita Shah,et al.  ST-Segment Elevation in Patients with Covid-19 — A Case Series , 2020, The New England journal of medicine.

[13]  Lisa Rosenbaum The Untold Toll - The Pandemic's Effects on Patients without Covid-19. , 2020, The New England journal of medicine.

[14]  Allan Schwartz,et al.  COVID-19 and Cardiovascular Disease , 2020, Circulation.