An endocrinologic follow-up study of operated cases of cryptorchism.

ABSTRACT Of 200 boys operated on for cryptorchism between the ages of 1 and 14 yr, 93 had a detailed follow-up examination between the ages of 12 and 27 yr and a further 29 answered a questionnaire only. Of the 93 subjects examined, 6 had some obvious endocrine disease: 3 had Klinefelter's syndrome (2 XXY and 1 XXYY), 2 hypogonadotrophic hypogonadism, and 1 germinal cell aplasia. The clinical features of these 6 cases and 2 others with initially azoospermic semen are described. In the other 85 subjects there was no pathologic delay of sexual development in relation to chronologic age, according to physical examination supplemented by radiographic determinations of skeletal age. Anatomically, the operation had been successful in all but 2 cases. Forty-one patients delivered a semen specimen. Among 22 patients who had undergone bilateral operation, 7 were normospermic, 12 oligospermic, and 3 azoospermic. Of 19 patients operated on for one-sided cryptorchism 14 were normospermic and 5 oligospermic. The ages ...