Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia

[1]  Q. Rao,et al.  RUNX1 inhibits proliferation and induces apoptosis of t(8;21) leukemia cells via KLF4-mediated transactivation of P57 , 2019, Haematologica.

[2]  C. Croce,et al.  miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC , 2018, Nature Communications.

[3]  Salam A. Assi,et al.  The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation , 2018, Cancer cell.

[4]  Jun Yin,et al.  UBXN2A enhances CHIP‐mediated proteasomal degradation of oncoprotein mortalin‐2 in cancer cells , 2018, Molecular oncology.

[5]  Xiaodong Zhang,et al.  Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia , 2018, Experimental & Molecular Medicine.

[6]  M. Mino‐Kenudson Immunohistochemistry for predictive biomarkers in non-small cell lung cancer. , 2017, Translational lung cancer research.

[7]  J. Brodsky,et al.  Guardians of the ERAD Galaxy , 2017, Cell.

[8]  Michael Q. Zhang,et al.  A novel epigenetic AML1‐ETO/THAP10/miR‐383 mini‐circuitry contributes to t(8;21) leukaemogenesis , 2017, EMBO molecular medicine.

[9]  Li-li Wang,et al.  Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia , 2017, Journal of Hematology & Oncology.

[10]  K. Rezvani UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer , 2016, International journal of molecular sciences.

[11]  Helene Kretzmer,et al.  metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data , 2016, Genome research.

[12]  David A. Knowles,et al.  Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants , 2015, Nature Communications.

[13]  N. Shen,et al.  AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation , 2014, Leukemia.

[14]  Meng Li,et al.  The function of targeted host genes determines the oncogenicity of HBV integration in hepatocellular carcinoma. , 2014, Journal of hepatology.

[15]  A. Abdullah,et al.  Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells , 2014, Cell Death and Disease.

[16]  M. Caligiuri,et al.  Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway. , 2013, Blood.

[17]  J. Brodsky,et al.  The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. , 2012, Physiological reviews.

[18]  R. Hartmann-Petersen,et al.  The Tissue-Specific Rep8/UBXD6 Tethers p97 to the Endoplasmic Reticulum Membrane for Degradation of Misfolded Proteins , 2011, PloS one.

[19]  J. Licht,et al.  Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. , 2010, Cancer cell.

[20]  Wei Li,et al.  BSMAP: whole genome bisulfite sequence MAPping program , 2009, BMC Bioinformatics.

[21]  O. Heidenreich,et al.  Transient depletion of RUNX1/RUNX1T1 by RNA interference delays tumour formation in vivo , 2009, Leukemia.

[22]  S. Fang,et al.  Regulation of ER-associated degradation via p97/VCP-interacting motif. , 2008, Biochemical Society transactions.

[23]  F. Lo‐Coco,et al.  Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. , 2007, Cancer cell.

[24]  S. Rosenberg,et al.  Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes. , 2003, Cancer Research.

[25]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.