Massive Thymic Deletion Results in Systemic Autoimmunity through Elimination of CD4+ CD25+ T Regulatory Cells
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[1] F. Ramsdell,et al. An essential role for Scurfin in CD4+CD25+ T regulatory cells , 2003, Nature Immunology.
[2] A. Rudensky,et al. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells , 2003, Nature Immunology.
[3] H. Mcdevitt,et al. CD4+ T Cells from Glutamic Acid Decarboxylase (GAD)65-specific T Cell Receptor Transgenic Mice Are Not Diabetogenic and Can Delay Diabetes Transfer , 2002, The Journal of experimental medicine.
[4] S. Jameson,et al. A Spontaneous CD8 T Cell-Dependent Autoimmune Disease to an Antigen Expressed Under the Human Keratin 14 Promoter1 , 2002, The Journal of Immunology.
[5] L. Klein,et al. Origin of regulatory T cells with known specificity for antigen , 2002, Nature Immunology.
[6] J. Miyazaki,et al. Generation of CD4+CD25+ Regulatory T Cells from Autoreactive T Cells Simultaneously with Their Negative Selection in the Thymus and from Nonautoreactive T Cells by Endogenous TCR Expression1 , 2002, The Journal of Immunology.
[7] P. Allen,et al. Dynamic visualization of a joint-specific autoimmune response through positron emission tomography , 2002, Nature Immunology.
[8] Ralph Weissleder,et al. Arthritis critically dependent on innate immune system players. , 2002, Immunity.
[9] C. Janeway,et al. Dual receptor T cells extend the immune repertoire for foreign antigens , 2002, Nature Immunology.
[10] C. Benoist,et al. Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes , 2001, Nature Immunology.
[11] Paul M. Allen,et al. Essential Role of Neutrophils in the Initiation and Progression of a Murine Model of Rheumatoid Arthritis1 , 2001, The Journal of Immunology.
[12] Philippa Marrack,et al. Autoimmune disease: why and where it occurs , 2001, Nature Medicine.
[13] K. Tung,et al. Endogenous Oocyte Antigens Are Required for Rapid Induction and Progression of Autoimmune Ovarian Disease Following Day-3 Thymectomy1 , 2001, The Journal of Immunology.
[14] A. Naji,et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide , 2001, Nature Immunology.
[15] M. Jordan,et al. Graded Deletion and Virus-Induced Activation of Autoreactive CD4+ T Cells1 , 2000, The Journal of Immunology.
[16] Ming-Lang Zhao,et al. Alterations in the Spinal Cord T Cell Repertoire During Relapsing Experimental Autoimmune Encephalomyelitis1 , 2000, The Journal of Immunology.
[17] D. Fremont,et al. Molecular Basis for Recognition of an Arthritic Peptide and a Foreign Epitope on Distinct MHC Molecules by a Single TCR1 , 2000, The Journal of Immunology.
[18] E. Unanue,et al. Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice. , 2000, Immunity.
[19] J. Bluestone,et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. , 2000, Immunity.
[20] Ethan M. Shevach,et al. Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific , 2000, The Journal of Immunology.
[21] K. Rajewsky,et al. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. , 1999, Immunity.
[22] E. Unanue,et al. Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells. , 1999, Journal of immunology.
[23] D. Margulies,et al. Post‐thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti‐H/K ATPase‐ reactive T cells , 1999, European journal of immunology.
[24] J. Lafaille,et al. Regulatory Cd4 Ϩ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis , 1998 .
[25] P. Allen,et al. In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery. , 1998, Journal of immunology.
[26] H. von Boehmer,et al. Allelic Inclusion of T Cell Receptor α Genes Poses an Autoimmune Hazard Due to Low-Level Expression of Autospecific Receptors , 1998 .
[27] Kathleen M. Smith,et al. Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance. , 1997, International immunology.
[28] D. Borchelt,et al. Hyperaccumulation of FAD-linked presenilin 1 variants in vivo , 1997, Nature Medicine.
[29] V. Kouskoff,et al. Organ-Specific Disease Provoked by Systemic Autoimmunity , 1996, Cell.
[30] B. Stockinger,et al. Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[31] S. Sakaguchi,et al. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation , 1996, The Journal of experimental medicine.
[32] Y. Xia,et al. Antigen compartmentation and T helper cell tolerance induction , 1996, The Journal of experimental medicine.
[33] M. Toda,et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. , 1995, Journal of immunology.
[34] V. Kouskoff,et al. A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice. , 1993, Journal of immunological methods.
[35] S. Tonegawa,et al. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice , 1993, Cell.
[36] M. B. Novick,et al. Association of a V beta 2-specific superantigen with a tumorigenic milk-borne mouse mammary tumor virus. , 1993, Journal of immunology.
[37] H. Boehmer,et al. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes , 1988, Nature.
[38] R. Good,et al. Post-thymectomy autoimmune phenomena in mice. II. Morphologic observations. , 1969, Laboratory investigation; a journal of technical methods and pathology.
[39] R. Good,et al. Postthymectomy wasting associated with autoimmune phenomena. I. Antiglobulin-positive anemia in A and C57BL-6 Ks mice. , 1967 .
[40] For April. , 1903 .