Adaptive control of left ventricular bypass assist devices

This paper presents a computer-based adaptive control system for left ventricular bypass assist devices consisting of air driven diaphragm pumps. The system provides for 1) synchronization of pumping with ECG signals and 2) control of atrial pressure at desired levels. The system design includes an adaptive control algorithm which is a self-tuning PID-controller based on pole placement. The performance of the system has been demonstrated by in vitro experiments_ on a mock circulatory system. When there is an increase in atrial pressure, the system responds with an increase in stroke volume. Following major changes in the circulatory system, the control algorithm retunes itself and restores the system to the desired state.

[1]  G. Goodwin,et al.  Deterministic convergence of a self-tuning regulator with covariance resetting , 1983 .

[2]  F D Altieri Status of implantable energy systems to actuate and control ventricular assist devices. , 1983, Artificial organs.

[3]  B C McInnis,et al.  Digital system for P-wave detection and synchronization of the artificial heart. , 1983, International journal of bio-medical computing.

[4]  H. Reul A hydraulic analog of the systemic and pulmonary circulation for testing artificial hearts , 1975 .

[5]  Dale E. Seborg,et al.  A new method for on‐line controller tuning , 1982 .

[6]  K Affeld,et al.  First experience with a mobile total artificial heart system. , 1980, Transactions - American Society for Artificial Internal Organs.

[7]  Hajime Akashi,et al.  A Design of an Adaptive Control System for Left Ventricular Assist , 1981 .

[8]  M. Tomizuka,et al.  Direct digital process control: Practice and algorithms for microprocessor application , 1978, Proceedings of the IEEE.

[9]  R K Jarvik,et al.  The total artificial heart. , 1981, Scientific American.

[10]  T. R. Fortescue,et al.  Implementation of self-tuning regulators with variable forgetting factors , 1981, Autom..

[11]  M. A. Fischetti Biomedical engineering: The quest for the ultimate artificial heart: The Salt Lake City achievement is only the beginning; in the offing are smaller, lighter systems, and eventually a fully implantable electrohydraulic heart , 1983, IEEE Spectrum.

[12]  H Harasaki,et al.  Experimental results for chronic left ventricular assist and total artificial heart development. , 1983, Artificial organs.

[13]  Karl Johan Åström,et al.  Theory and applications of adaptive control - A survey , 1983, Autom..

[14]  G Rosenberg,et al.  A cam-type electric motor-driven left ventricular assist device. , 1982, Journal of biomechanical engineering.

[15]  E. F. Vogel,et al.  Application of an Adaptive Pole-Zero Placement Controller to Chemical Processes with Variable Dead Time , 1982, 1982 American Control Conference.