Optical colorimetric sensor strip for direct readout glucose measurement.

A novel direct readout colorimetric optical glucose sensor strip was constructed based on a three-layer film, including a green-emitted CdTe/CdS quantum dots (QDs) layer as a stable color background, a red-fluorescent platinum-porphyrin oxygen-sensing layer and a glucose oxidase layer. The sensor achieved high resolution (up to 0.2 mmol L(-1)) glucose determination with a detection range from 0 to 3.0 mmol L(-1). A "glucose ruler" which acts as a glucose standard colorimetric card was obtained. Glucose concentration could easily be directly readout using the "glucose ruler", which made the glucose determination rapid, convenient and easy. The effects of pH, salinity and temperature were systematically investigated. The prepared sensor was finally applied for glucose sample analysis, compared with the "glucose ruler", accurate results could be directly readout.

[1]  Leon A Terry,et al.  The application of biosensors to fresh produce and the wider food industry. , 2005, Journal of agricultural and food chemistry.

[2]  D R Walt,et al.  Dual-analyte fiber-optic sensor for the simultaneous and continuous measurement of glucose and oxygen. , 1995, Analytical chemistry.

[3]  L. C. Clark,et al.  ELECTRODE SYSTEMS FOR CONTINUOUS MONITORING IN CARDIOVASCULAR SURGERY , 1962 .

[4]  I Klimant,et al.  Sol-gel based glucose biosensors employing optical oxygen transducers, and a method for compensating for variable oxygen background. , 2000, Biosensors & bioelectronics.

[5]  J. Winderickx,et al.  Glucose-sensing mechanisms in eukaryotic cells. , 2001, Trends in biochemical sciences.

[6]  Ichiro Okura,et al.  Photostable Optical Oxygen Sensing Material: Platinum Tetrakis(pentafluorophenyl)porphyrin Immobilized in Polystyrene , 1997 .

[7]  O. Wolfbeis Fiber-optic chemical sensors and biosensors. , 2000, Analytical chemistry.

[8]  Preparation and characterization of glass embedding photoluminescent CdTe nanocrystals , 2004 .

[9]  N. Murase,et al.  Synthesis of highly luminescent glasses incorporating cdte nanocrystals through sol-gel processing. , 2004, Langmuir : the ACS journal of surfaces and colloids.

[10]  J. Lakowicz,et al.  Wavelength-ratiometric and colorimetric probes for glucose determination. , 2006, Dyes and pigments : an international journal.

[11]  Ling Lin,et al.  Novel BOD optical fiber biosensor based on co-immobilized microorganisms in ormosils matrix. , 2006, Biosensors & bioelectronics.

[12]  Viviana Scognamiglio,et al.  Protein-Based Biosensors for Diabetic Patients , 2004, Journal of Fluorescence.

[13]  Xiao-ru Wang,et al.  Reversible Optical Sensor Strip for Oxygen , 2008 .

[14]  S. Daunert,et al.  Fluorescence Glucose Detection: Advances Toward the Ideal In Vivo Biosensor , 2004, Journal of Fluorescence.

[15]  Dan Xiao,et al.  A fluorescent glucose biosensor based on immobilized glucose oxidase on bamboo inner shell membrane. , 2006, Biosensors & bioelectronics.

[16]  Ichiro Okura,et al.  Platinum tetrakis(pentafluorophenyl)porphyrin immobilized in polytrifluoroethylmethacrylate film as a photostable optical oxygen detection material , 2001 .

[17]  Binghe Wang,et al.  Progress in Boronic Acid-Based Fluorescent Glucose Sensors , 2004, Journal of Fluorescence.

[18]  Xi Chen,et al.  An optical biosensor for the rapid determination of glucose in human serum , 2008 .

[19]  D Marshall Porterfield,et al.  Measuring metabolism and biophysical flux in the tissue, cellular and sub-cellular domains: recent developments in self-referencing amperometry for physiological sensing. , 2007, Biosensors & bioelectronics.

[20]  E. Baena-González,et al.  Sugar sensing and signaling in plants: conserved and novel mechanisms. , 2006, Annual review of plant biology.

[21]  David Carling,et al.  The AMP-activated protein kinase cascade--a unifying system for energy control. , 2004, Trends in biochemical sciences.

[22]  S. Hjertén,et al.  Electroosmosis- and pressure-driven chromatography in chips using continuous beds. , 2000, Analytical chemistry.

[23]  O. Wolfbeis,et al.  Oxygen optrode for use in a fiber-optic glucose biosensor. , 1990, Analytical chemistry.

[24]  G. S. Wilson,et al.  Can continuous glucose monitoring be used for the treatment of diabetes. , 1992, Analytical chemistry.

[25]  Chi K. Chang,et al.  Electronic spectroscopy, photophysical properties, and emission quenching studies of an oxidatively robust perfluorinated platinum porphyrin. , 2004, Inorganic chemistry.

[26]  Sejin Park,et al.  Electrochemical non-enzymatic glucose sensors. , 2006, Analytica chimica acta.

[27]  O. Yamauchi,et al.  Dipolar ruthenium-ammine complexes with 4,4′-bipyridinium ions accessible for both amperometric and colorimetric glucose sensors , 2006 .

[28]  N. Evans,et al.  Fluorescence-based glucose sensors. , 2005, Biosensors & bioelectronics.

[29]  Joseph Wang Electrochemical glucose biosensors. , 2008, Chemical reviews.

[30]  Kazunori Kataoka,et al.  Simple and precise preparation of a porous gel for a colorimetric glucose sensor by a templating technique. , 2003, Angewandte Chemie.

[31]  Adam Heller,et al.  Electrochemical glucose sensors and their applications in diabetes management. , 2008, Chemical reviews.