Use and Action of Chlorpromazine in Psychoneuroses

was a marked increase in the absolute amount and percentage of nitrogen retained. The increase in food intake and in body weight is apparent. The changes in the percentage of nitrogen retained were due to changes in the proportion of ingested nitrogen excreted in the urine (Table II), whereas the percentage of the ingested nitrogen that was excreted in the faeces remained relatively constant. It is apparent (Chart) that nitrogen equilibrium was restored when the insulin injections were stopped. This latter change in nitrogen balance was accompanied by a fall in body weight. The loss of weight was due to the loss of fat or water or of both. No appreciable amount of protein was lost, since the animals did not exhibit a significantly negative nitrogen balance.