Adrenergic receptor agonists induce the differentiation of pluripotent stem cell-derived hepatoblasts into hepatocyte-like cells

[1]  Y. Toh,et al.  Cost-effective differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules. , 2015, Biomaterials.

[2]  Elena Naumovska,et al.  Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells , 2015, Stem cell reports.

[3]  D. Stainier,et al.  VMAT2 identified as a regulator of late-stage β-cell differentiation. , 2014, Nature chemical biology.

[4]  S. Yamanaka,et al.  Efficient and Rapid Induction of Human iPSCs/ESCs into Nephrogenic Intermediate Mesoderm Using Small Molecule-Based Differentiation Methods , 2014, PloS one.

[5]  S. Yamanaka,et al.  An Efficient Nonviral Method to Generate Integration‐Free Human‐Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells , 2013, Stem cells.

[6]  Zheng Li,et al.  Generation, characterization and potential therapeutic applications of mature and functional hepatocytes from stem cells , 2013, Journal of cellular physiology.

[7]  Chad A. Cowan,et al.  Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells , 2013, Nature Communications.

[8]  Takashi Aoi,et al.  Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells , 2012, Proceedings of the National Academy of Sciences.

[9]  Haiyan Zhang,et al.  Efficient generation of functional hepatocyte‐like cells from human fetal hepatic progenitor cells in vitro , 2012, Journal of cellular physiology.

[10]  Hung-Chih Kuo,et al.  Rapid generation of mature hepatocyte‐like cells from human induced pluripotent stem cells by an efficient three‐step protocol , 2012, Hepatology.

[11]  Magnus Ingelman-Sundberg,et al.  Hepatocyte-like cells derived from human embryonic stem cells specifically via definitive endoderm and a progenitor stage. , 2010, Journal of biotechnology.

[12]  Stephen Dalton,et al.  Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells , 2010, Hepatology.

[13]  S. Schreiber,et al.  Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. , 2009, Cell stem cell.

[14]  S. Schreiber,et al.  A small molecule that directs differentiation of human ESCs into the pancreatic lineage. , 2009, Nature chemical biology.

[15]  Catherine Payne,et al.  Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling , 2008, Proceedings of the National Academy of Sciences.

[16]  Robert Lanza,et al.  Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells , 2008, Stem cells.

[17]  Chad A. Cowan,et al.  Marked differences in differentiation propensity among human embryonic stem cell lines , 2008, Nature Biotechnology.

[18]  Shulan Tian,et al.  Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.

[19]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[20]  T. Graf.  Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors. , 2007 .

[21]  J. Itskovitz‐Eldor,et al.  Directed differentiation of human embryonic stem cells into functional hepatic cells , 2007, Hepatology.

[22]  Hayley S. Brown,et al.  Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies , 2007, Drug metabolism reviews.

[23]  Peter G Schultz,et al.  Small molecules that induce cardiomyogenesis in embryonic stem cells. , 2004, Journal of the American Chemical Society.

[24]  Frank Stahl,et al.  Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. , 2003, Drug metabolism and disposition: the biological fate of chemicals.

[25]  D. Court,et al.  A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. , 2001, Genomics.

[26]  Y. Ito,et al.  Retroviral gene transfer of signaling molecules into murine fetal hepatocytes defines distinct roles for the STAT3 and ras pathways during hepatic development , 2000, Hepatology.

[27]  J. Thomson,et al.  Embryonic stem cell lines derived from human blastocysts. , 1998, Science.

[28]  A. Strosberg,et al.  Structure, function, and regulation of adrenergic receptors , 1993, Protein science : a publication of the Protein Society.

[29]  M. Benito,et al.  Regulation of albumin expression in fetal rat hepatocytes cultured under proliferative conditions: Role of epidermal growth factor and hormones , 1992, Journal of cellular physiology.

[30]  M. Caron,et al.  Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins. , 1988, The Journal of biological chemistry.

[31]  G. Michalopoulos,et al.  Induction of DNA synthesis in cultured rat hepatocytes through stimulation of alpha 1 adrenoreceptor by norepinephrine. , 1985, Science.

[32]  D. Friedman,et al.  Hormonal regulation of DNA synthesis in primary cultures of adult rat hepatocytes: action of glucagon. , 1981, Experimental cell research.

[33]  N. Bucher,et al.  DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: Effects of epidermal growth factor, insulin, glucagon, and cyclic‐AMP , 1981, Journal of cellular physiology.

[34]  D. Friedman,et al.  Hormonal stimulation of DNA synthesis in primary cultures of adult rat hepatocytes. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[35]  A. Guillouzo,et al.  General review on in vitro hepatocyte models and their applications. , 2010, Methods in molecular biology.

[36]  A. Dhawan,et al.  Human hepatocyte transplantation overview. , 2009, Methods in molecular biology.