Adverse Immune Reactions to Drugs (Gold, Procainamide) and Environmental Chemicals (Mercury, Platinum): The Role of Phagocytic Cells in Generating Immunogenic Metabolites

[1]  S. Pals,et al.  T Cell‐dependent B‐Cell proliferation and activation induced by administration of the drug diphenylhydantoin to mice , 2007, Hematological oncology.

[2]  E. van Vliet,et al.  MHC control of IL-4-dependent enhancement of B cell Ia expression and Ig class switching in mice treated with mercuric chloride. , 1993, International archives of allergy and immunology.

[3]  M. Uhrberg,et al.  Murine systemic autoimmune disease induced by mercuric chloride (HgCl2): Hg-specific helper T-cells react to antigen stored in macrophages. , 1993, International journal of immunopharmacology.

[4]  G. Kingsley,et al.  Activation of gold-reactive T lymphocytes in rheumatoid arthritis patients treated with gold. , 1992, Arthritis and rheumatism.

[5]  G. Geier,et al.  Extremely rapid Au(I)-transfer reactions between S-donor ligands , 1991 .

[6]  M. Goldman,et al.  TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity. , 1991, Immunology today.

[7]  C. Pfeiffer,et al.  IL-4 is required for the IgE and IgG1 increase and IgG1 autoantibody formation in mice treated with mercuric chloride. , 1991, Journal of immunology.

[8]  J. Uetrecht,et al.  N-Chlorination and oxidation of procainamide by myeloperoxidase: toxicological implications. , 1991, Chemical research in toxicology.

[9]  T. Pullar.  Disease modifying drugs for rheumatoid arthritis: yesterday's treatment today or today's treatment tomorrow? , 1990, British journal of clinical pharmacology.

[10]  P. Kind,et al.  Adverse immune reactions to gold. I. Chronic treatment with an Au(I) drug sensitizes mouse T cells not to Au(I), but to Au(III) and induces autoantibody formation. , 1990, Journal of immunology.

[11]  M. Ogata,et al.  Exhaled metallic mercury in acatalasemic, hypocatalasemic and normal mice injected with mercury (II) chloride. , 1990, Acta medica Okayama.

[12]  B. Eley.  A study of mercury redistribution, excretion and renal pathology in guinea-pigs implanted with powdered dental amalgam for between 2 and 4 years. , 1990, Journal of experimental pathology.

[13]  G. Warfvinge,et al.  Spontaneous lymphocytic infiltrates of oral mucosa in HgCl2 induced autoimmunity of BN rats: phenotypic characteristics and contact hypersensitivity to Hg. , 1990, Regional immunology.

[14]  R. Klausner,et al.  Class II MHC molecules can use the endogenous pathway of antigen presentation , 1990, Nature.

[15]  E. Appella,et al.  Competition for antigen presentation in living cells involves exchange of peptides bound by class II MHC molecules , 1989, Nature.

[16]  J. Bruijn,et al.  Immunological alterations inducible by mercury compounds. III. H‐2A acts as an immune response and H‐2E as an immune “suppression” locus for HgCl2‐induced antinucleolar autoantibodies , 1989, European journal of immunology.

[17]  P. Hultman,et al.  Mercury induced B-cell activation and antinuclear antibodies in mice. , 1989, Journal of clinical & laboratory immunology.

[18]  N. Ballatori,et al.  Mercury vapor uptake and hydrogen peroxide detoxification in human and mouse red blood cells. , 1988, Toxicology and applied pharmacology.

[19]  P. Druet,et al.  Autoreactive T cells in mercury‐induced autoimmunity. Demonstration by limiting dilution analysis , 1988, European journal of immunology.

[20]  J. Uetrecht.  Mechanism of drug-induced lupus. , 1988, Chemical research in toxicology.

[21]  J. Uetrecht,et al.  Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells. , 1988, The Journal of pharmacology and experimental therapeutics.

[22]  P. Hultman,et al.  Mercury induced antinuclear antibodies in mice: characterization and correlation with renal immune complex deposits. , 1988, Clinical and experimental immunology.

[23]  R Pasquier,et al.  Autoreactive T cells in mercury-induced autoimmunity. Ability to induce the autoimmune disease. , 1988, Journal of immunology.

[24]  H. Gleichmann,et al.  Specific Immunity to Streptozocin: Cellular Requirements for Induction of Lymphoproliferation , 1988, Diabetes.

[25]  U. Hurtenbach,et al.  Immunity to D-penicillamine: genetic, cellular, and chemical requirements for induction of popliteal lymph node enlargement in the mouse. , 1987, Journal of immunology.

[26]  I. Egorov,et al.  Mercuric chloride-, gold sodium thiomalate-, and D-penicillamine-induced antinuclear antibodies in mice. , 1986, Toxicology and applied pharmacology.

[27]  F. Hirsch,et al.  Autoreactive T cells in mercury-induced autoimmune disease: in vitro demonstration. , 1986, Journal of immunology.

[28]  C. Dillard,et al.  Are some major in vivo effects of gold related to microenvironments of decreased selenium? , 1986, Medical hypotheses.

[29]  R. Cook,et al.  Proliferative signals for suppressor T cells. Helper cells stimulated with pokeweed mitogen in vitro produce a suppressor cell growth factor. , 1986, The Journal of clinical investigation.

[30]  U. Hurtenbach,et al.  Specific sensitization of Lyt-1+2- T cells to spleen cells modified by the drug D-penicillamine or a stereoisomer. , 1986, Journal of immunology.

[31]  D. Smith,et al.  Forty-seven years experience with gold therapy in 1,019 rheumatoid arthritis patients. , 1985, Seminars in arthritis and rheumatism.

[32]  S. Pals,et al.  Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases. , 1984, Immunology today.

[33]  J. Pepys,et al.  Immunological responses to complex salts of platinum. II. Enhanced IgE antibody responses to ovalbumin with concurrent administration of platinum salts in the rat. , 1984, Clinical and experimental immunology.

[34]  L Lasagna,et al.  Drug discontinuations in the United Kingdom and the United States, 1964 to 1983: Issues of safety , 1984, Clinical pharmacology and therapeutics.

[35]  H. Grey,et al.  Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing , 1983, The Journal of experimental medicine.

[36]  I. Bernstein,et al.  Pulmonary hyperreactivity in cynomolgus monkeys (Macaca fascicularis) from nose-only inhalation exposure to disodium hexachloroplatinate, Na2PtCl6. , 1983, Toxicology and applied pharmacology.

[37]  E. Thorsby,et al.  HLA DR antigens and gold toxicity. , 1983, Annals of the rheumatic diseases.

[38]  G. Porter.  Nephrotoxic Mechanisms of Drugs and Environmental Toxins , 1982 .

[39]  K. Göransson,et al.  Oral lichen planus and contact allergy to mercury. , 1982, International journal of oral surgery.

[40]  J. Oates,et al.  Covalent binding of procainamide in vitro and in vivo to hepatic protein in mice. , 1981, Drug metabolism and disposition: the biological fate of chemicals.

[41]  H. Gleichmann,et al.  Studies on the mechanism of drug sensitization: T-cell-dependent popliteal lymph node reaction to diphenylhydantoin. , 1981, Clinical immunology and immunopathology.

[42]  W. Weber,et al.  Antinuclear antibodies related to acetylator phenotype in mice. , 1980, The Journal of pharmacology and experimental therapeutics.

[43]  P. Druet,et al.  Immune type glomerulonephritis induced by HgCl2 in the Brown Norway rat. , 1978, Annales d'immunologie.

[44]  C. Dahlgren,et al.  The inhibition of polymorphonuclear leukocyte cytotoxicity by dapsone. A possible mechanism in the treatment of dermatitis herpetiformis. , 1978, The Journal of clinical investigation.

[45]  J. Oates,et al.  Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome. , 1978, The New England journal of medicine.

[46]  T W Clarkson,et al.  Role of catalase in the oxidation of mercury vapor. , 1978, Biochemical pharmacology.

[47]  P. Sadler,et al.  Reactions of gold(III) ions with ribonuclease A and methionine derivatives in aqueous solution. , 1977, Biochimica et biophysica acta.

[48]  H. Gleichmann,et al.  Autoimmunization and Lymphomagenesis in Parent‐F1 Combinations Differing at the Major Histocompatibility Complex: Model for Spontaneous Disease Caused by Altered Self‐Antigens? , 1976, Transplantation reviews.

[49]  F. Ruff,et al.  Platinum and platinosis. Allergy and histamine release due to some platinum salts. , 1969, Archives of environmental health.

[50]  J. Rungby,et al.  Toxicity and ultrastructural localization of mercuric chloride in cultured murine macrophages , 2004, Archives of Toxicology.

[51]  A. Jones,et al.  Non-steroidal anti-inflammatory drug usage and requirement in elderly acute hospital admissions. , 1992, British journal of rheumatology.

[52]  J. Uetrecht.  The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions. , 1992, Drug metabolism reviews.

[53]  J. Uetrecht,et al.  Comparative metabolism and covalent binding of procainamide by human leukocytes. , 1992, Drug metabolism and disposition: the biological fate of chemicals.

[54]  H. Schuppe,et al.  T-cell-dependent popliteal lymph node reactions to platinum compounds in mice. , 1992, International archives of allergy and immunology.

[55]  H. Shionoya,et al.  Popliteal lymph node enlargement induced by procainamide. , 1992, International journal of immunopharmacology.

[56]  F. Sinigaglia,et al.  Gold-specific T cells in rheumatoid arthritis patients treated with gold. , 1992, The Journal of clinical investigation.

[57]  B. Bellon,et al.  Chemical-induced autoimmunity. , 1991, Immunology series.

[58]  B. Guilbert,et al.  Experimental gold-induced autoimmunity. , 1991, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[59]  J. Rothbard,et al.  Interactions between Immunogenic Peptides and MHC Proteins , 1991 .

[60]  L. Friberg,et al.  Toxicology of Inorganic Mercury , 1990 .

[61]  A. Dayan,et al.  Immunotoxicity of metals and immunotoxicology , 1990 .

[62]  A. Lanzavecchia,et al.  Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. , 1990, Annual review of immunology.

[63]  H. Iwai,et al.  Antinucleolar autoantibody induced in mice by mercuric chloride. , 1990, Industrial health.

[64]  G. Rosner,et al.  Allergenic Potential of Platinum Compounds , 1990 .

[65]  H. Schuppe,et al.  Tests for Predicting Sensitization to Chemicals and Their Metabolites, with Special Reference to Heavy Metals , 1990 .

[66]  A. Townsend,et al.  Antigen recognition by class I-restricted T lymphocytes. , 1989, Annual review of immunology.

[67]  R. Lührmann,et al.  Mercuric chloride induces autoantibodies against U3 small nuclear ribonucleoprotein in susceptible mice. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[68]  G. Danscher,et al.  Autometallographic demonstration of gold uptake in cultured synovial fluid cells from patients with rheumatoid arthritis. , 1989, Scandinavian journal of rheumatology.

[69]  K. Degitz,et al.  Immunological alterations inducible by mercury compounds. II. HgCl2 and gold sodium thiomalate enhance serum IgE and IgG concentrations in susceptible mouse strains. , 1989, International archives of allergy and applied immunology.

[70]  R. Coffman,et al.  TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. , 1989, Annual review of immunology.

[71]  J. D. de Bakker,et al.  The popliteal lymph node assay in mice to screen for the immune disregulating potential of chemicals--a preliminary study. , 1989, International journal of immunopharmacology.

[72]  J. Groten,et al.  Popliteal lymph node reactions in mice induced by the drug zimeldine. , 1989, International journal of immunopharmacology.

[73]  J. Uetrecht,et al.  Metabolism of procainamide to a hydroxylamine by human neutrophils and mononuclear leukocytes. , 1988, Chemical research in toxicology.

[74]  T. Delovitch,et al.  Influence of antigen processing on immune responsiveness. , 1988, Immunology today.

[75]  W. Seinen,et al.  Structural requirements for hydantoins and 2-thiohydantoins to induce lymphoproliferative popliteal lymph node reactions in the mouse. , 1988, International journal of immunopharmacology.

[76]  T. Radaszkiewicz,et al.  Immunopathological signs in mice treated with mercury compounds--I. Identification by the popliteal lymph node assay of responder and nonresponder strains. , 1988, International journal of immunopharmacology.

[77]  J. Rossert,et al.  HgCl2 induces nonspecific immunosuppression in Lewis rats , 1987, European journal of immunology.

[78]  J. Pepys,et al.  Enhancement of antibody production by mercury and platinum group metal halide salts. Kinetics of total and ovalbumin-specific IgE synthesis. , 1986, International archives of allergy and applied immunology.

[79]  Lipsky Pe.  Remittive therapy in rheumatoid arthritis: clinical uses and mechanisms of action. , 1984 .

[80]  R. Murdoch.  Immunological responses to complex salts of platinum , 1983 .

[81]  H. Ohmori,et al.  A mechanism of the augmentation of antibody response in vitro by 2-mercaptoethanol: facilitation of cystine uptake in murine lymphocytes. , 1982, International journal of immunopharmacology.

[82]  I. Glurich,et al.  Mercuric Chloride-Induced Immunologically Mediated Diseases in Experimental Animals , 1982 .

[83]  F. Hirsch,et al.  Genetic Control of Mercury-Induced Immune Response in the Rat , 1982 .

[84]  F. Hirsch,et al.  Polyclonal effect of HgCl2 in the rat, its possible role in an experimental autoimmune disease , 1982, European journal of immunology.

[85]  C. Shaw,et al.  Oxidative cleavage of peptide and protein disulphide bonds by gold(III): a mechanism for gold toxicity , 1981 .

[86]  C. Mandet,et al.  Immune-type glomerulonephritis induced in the Brown-Norway rat with mercury-containing pharmaceutical products. , 1981, Nephron.

[87]  D. H. Brown,et al.  The chemistry of the gold drugs used in the treatment of rheumatoid arthritis , 1980 .

[88]  P. Davis.  Undesirable effects of gold salts. , 1979, The Journal of rheumatology. Supplement.