Determination of lead in blood and urine by anodic stripping voltammetry.

An anodic stripping procedure for determining lead in blood and urine was evaluated, and methods of calibration were developed. The technique requires as little as 50 µl of blood or 0.5 ml of urine. Comparisons were made between results obtained by anodic stripping voltammetry, for finger-puncture blood, and by atomic absorption spectrophotometry, for venous blood from 200 children. The two methods were also compared with respect to lead in urines from patients hospitalized for suspected lead poisoning and in urines from normal healthy volunteers. Major advantages of the anodic stripping method are its increased sensitivity and lower cost as compared to many current methods for detecting and measuring lead