DOT for TB: Is It for Everyone?
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Treatment of active TB is challenging because patients must take multiple medications for at least 6 months. Directly observed therapy (DOT) is
[1] Christopher B. Seaman,et al. Tuberculosis treatment outcomes: directly observed therapy compared with self-administered therapy. , 2004, American journal of respiratory and critical care medicine.
[2] R. Reves,et al. How much directly observed therapy is enough? , 2004, American Journal of Respiratory and Critical Care Medicine.