Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients

[1]  M. McCarter,et al.  Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo , 2014, Retrovirology.

[2]  Y. Lévy,et al.  IL-7 Modulates In Vitro and In Vivo Human Memory T Regulatory Cell Functions through the CD39/ATP Axis , 2013, The Journal of Immunology.

[3]  C. Rouzioux,et al.  The Th17/Treg Ratio, IL-1RA and sCD14 Levels in Primary HIV Infection Predict the T-cell Activation Set Point in the Absence of Systemic Microbial Translocation , 2013, PLoS pathogens.

[4]  C. Rouzioux,et al.  Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts. , 2013, The Journal of antimicrobial chemotherapy.

[5]  J. Brenchley Mucosal immunity in human and simian immunodeficiency lentivirus infections , 2013, Mucosal Immunology.

[6]  Brigitte Autran,et al.  Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study , 2013, PLoS pathogens.

[7]  A. Sönnerborg,et al.  Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. , 2013, Blood.

[8]  C. Deming,et al.  Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. , 2013, The Journal of clinical investigation.

[9]  Jay K Kolls,et al.  The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin. , 2013, Annual review of pathology.

[10]  M. Lederman,et al.  IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa. , 2012, Blood.

[11]  R. Kaul,et al.  A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis , 2012, Mucosal Immunology.

[12]  S. Sieg,et al.  Faculty Opinions recommendation of Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. , 2012 .

[13]  A. Haase,et al.  Lymphoid tissue structure and HIV-1 infection: life or death for T cells. , 2012, Trends in immunology.

[14]  Y. Belkaid,et al.  Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection , 2012, Mucosal Immunology.

[15]  A. Roverato,et al.  Premature age-related comorbidities among HIV-infected persons compared with the general population. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[16]  H. Harbo,et al.  Identification of Human NK17/NK1 Cells , 2011, PloS one.

[17]  J. García,et al.  Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers , 2011, Journal of Virology.

[18]  O. Lantz,et al.  Mucosal-associated invariant T cells: unconventional development and function. , 2011, Trends in immunology.

[19]  R. Kaul,et al.  Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy , 2011, AIDS.

[20]  M. Si-Tahar,et al.  Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells , 2011, The Journal of experimental medicine.

[21]  V. Kuchroo,et al.  γδ T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism. , 2010, Immunity.

[22]  S. Pittaluga,et al.  Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections , 2010, PLoS pathogens.

[23]  O. Lantz,et al.  Antimicrobial activity of mucosal-associated invariant T cells , 2010, Nature Immunology.

[24]  M. McCarter,et al.  Human Intestinal Lamina Propria CD1c+ Dendritic Cells Display an Activated Phenotype at Steady State and Produce IL-23 in Response to TLR7/8 Stimulation , 2010, The Journal of Immunology.

[25]  Jeff E. Mold,et al.  Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease , 2010, Science Translational Medicine.

[26]  G. Franchini,et al.  Th17 cells in pathogenic simian immunodeficiency virus infection of macaques , 2010, Current opinion in HIV and AIDS.

[27]  Michael D. George,et al.  Th17 cells, HIV and the gut mucosal barrier , 2010, Current opinion in HIV and AIDS.

[28]  L. Cosmi,et al.  Evidence for a cross-talk between human neutrophils and Th17 cells. , 2010, Blood.

[29]  S. Durham,et al.  Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. , 2009, The Journal of clinical investigation.

[30]  K. Mills,et al.  Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. , 2009, Immunity.

[31]  H. Spits,et al.  Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells , 2009, Nature Immunology.

[32]  Mario Roederer,et al.  Emerging concepts in the immunopathogenesis of AIDS. , 2009, Annual review of medicine.

[33]  Yang Xie,et al.  Statistical methods of background correction for Illumina BeadArray data , 2009, Bioinform..

[34]  J. Lennerz,et al.  A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity , 2009, Nature.

[35]  Carole R. Baskin,et al.  Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection , 2009, PLoS pathogens.

[36]  Avettand‐Fènoël Véronique,et al.  LTR real‐time PCR for HIV‐1 DNA quantitation in blood cells for early diagnosis in infants born to seropositive mothers treated in HAART area (ANRS CO 01) , 2009, Journal of medical virology.

[37]  D. Rifkin,et al.  Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. , 2008, Cell host & microbe.

[38]  D. Douek,et al.  Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. , 2008, Blood.

[39]  T. Chun,et al.  Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses , 2008, Mucosal Immunology.

[40]  T. Marafioti,et al.  Labeling of Multiple Cell Markers and mRNA Using Automated Apparatus , 2008, Applied immunohistochemistry & molecular morphology : AIMM.

[41]  S. Pileri,et al.  Novel markers of normal and neoplastic human plasmacytoid dendritic cells. , 2008, Blood.

[42]  H. Stein,et al.  Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. , 2006, Blood.

[43]  Christine Hogan,et al.  Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4+ T Lymphocytes from Effector Sites in the Gastrointestinal Tract , 2004, The Journal of experimental medicine.

[44]  D. Price,et al.  CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract , 2004, The Journal of experimental medicine.

[45]  Gordon K Smyth,et al.  Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .

[46]  J. Flamm,et al.  Severe CD4+ T-Cell Depletion in Gut Lymphoid Tissue during Primary Human Immunodeficiency Virus Type 1 Infection and Substantial Delay in Restoration following Highly Active Antiretroviral Therapy , 2003, Journal of Virology.

[47]  Michael P Busch,et al.  Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection , 2003, AIDS.

[48]  Terence P. Speed,et al.  A comparison of normalization methods for high density oligonucleotide array data based on variance and bias , 2003, Bioinform..

[49]  D. Botstein,et al.  Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[50]  H. Spits,et al.  The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling , 2011, Nature Immunology.

[51]  Jeffrey N. Martin,et al.  Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. , 2008, The Journal of infectious diseases.

[52]  C. Rouzioux,et al.  LTR Real-Time PCR for HIV-1 DNA Quantitation in Blood Cells for Early Diagnosis in Infants Born to Seropositive Mothers Treated in HAART Area ( ANRS CO 01 ) , 2008 .

[53]  Cheng Li,et al.  Adjusting batch effects in microarray expression data using empirical Bayes methods. , 2007, Biostatistics.