E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo

[1]  S. Goerdt,et al.  Macrophage activation and polarization: nomenclature and experimental guidelines. , 2014, Immunity.

[2]  S. Gordon,et al.  The M1 and M2 paradigm of macrophage activation: time for reassessment , 2014, F1000prime reports.

[3]  J. V. Van Ginderachter,et al.  E‐cadherin: From epithelial glue to immunological regulator , 2013, European journal of immunology.

[4]  Patrick De Baetselier,et al.  Pivotal Advance: Arginase‐1‐independent polyamine production stimulates the expression of IL‐4‐induced alternatively activated macrophage markers while inhibiting LPS‐induced expression of inflammatory genes , 2012, Journal of leukocyte biology.

[5]  A. Mantovani,et al.  Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs. , 2012, Blood.

[6]  J. Piette,et al.  Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints. , 2011, American journal of physiology. Lung cellular and molecular physiology.

[7]  M. Oursler.  Recent advances in understanding the mechanisms of osteoclast precursor fusion , 2010, Journal of cellular biochemistry.

[8]  S. Gordon,et al.  Alternative activation of macrophages: mechanism and functions. , 2010, Immunity.

[9]  D. Lowy,et al.  E-cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of Rho GTPases , 2010, Oncogene.

[10]  A. Satoskar,et al.  Early removal of alternatively activated macrophages leads to Taenia crassiceps cysticercosis clearance in vivo. , 2010, International journal for parasitology.

[11]  L. Brossay,et al.  Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling. , 2009, Blood.

[12]  H. Pircher,et al.  Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes. , 2009, Blood.

[13]  P. Loke.  Faculty Opinions recommendation of Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung. , 2009 .

[14]  A. Murphy,et al.  Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung , 2009, The Journal of experimental medicine.

[15]  A. Smith,et al.  Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis , 2009, PLoS pathogens.

[16]  A. Tomassetti,et al.  E-cadherin directly contributes to PI3K/AKT activation by engaging the PI3K-p85 regulatory subunit to adherens junctions of ovarian carcinoma cells , 2009, Oncogene.

[17]  M. Merad,et al.  Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes , 2008, The Journal of experimental medicine.

[18]  B. Li,et al.  IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma1 , 2008, The Journal of Immunology.

[19]  S. Gordon,et al.  Essential Role of DAP12 Signaling in Macrophage Programming into a Fusion-Competent State , 2008, Science Signaling.

[20]  H. Pasolli,et al.  Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer , 2008, Proceedings of the National Academy of Sciences.

[21]  I. Mikhailenko,et al.  IL‐4 promotes the formation of multinucleated giant cells from macrophage precursors by a STAT6‐dependent, homotypic mechanism: contribution of E‐cadherin , 2007, Journal of leukocyte biology.

[22]  T. Hanke,et al.  Characterization of mouse CD4 T cell subsets defined by expression of KLRG1 , 2007, European journal of immunology.

[23]  Y. Belkaid,et al.  A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism , 2007, The Journal of experimental medicine.

[24]  W. Gause,et al.  Alternatively activated macrophages in helminth infections. , 2007, Current opinion in immunology.

[25]  G. Leclercq,et al.  KLRG1 binds cadherins and preferentially associates with SHIP-1. , 2007, International immunology.

[26]  S. Gordon,et al.  Macrophage fusion induced by IL‐4 alternative activation is a multistage process involving multiple target molecules , 2007, European journal of immunology.

[27]  Jos Jonkers,et al.  Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. , 2006, Cancer cell.

[28]  R. M. Z. D. Santos,et al.  Four whole-istic aspects of schistosome granuloma biology: fractal arrangement, internal regulation, autopoietic component and closure. , 2006, Memorias do Instituto Oswaldo Cruz.

[29]  P. De Baetselier,et al.  Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. , 2006, Blood.

[30]  N. Matsumoto,et al.  Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity , 2006, The Journal of experimental medicine.

[31]  H. Pasolli,et al.  p120-Catenin Mediates Inflammatory Responses in the Skin , 2006, Cell.

[32]  Y. Toyama,et al.  DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells , 2005, The Journal of experimental medicine.

[33]  Y. Belkaid,et al.  A Role for CD103 in the Retention of CD4+CD25+ Treg and Control of Leishmania major Infection1 , 2005, The Journal of Immunology.

[34]  B. Dahal,et al.  Macrophage galactose‐type C‐type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation , 2005, Journal of leukocyte biology.

[35]  Silvano Sozzani,et al.  The chemokine system in diverse forms of macrophage activation and polarization. , 2004, Trends in immunology.

[36]  A. Satoskar,et al.  A STAT4-Dependent Th1 Response Is Required for Resistance to the Helminth Parasite Taenia crassiceps , 2004, Infection and Immunity.

[37]  F. Brombacher,et al.  Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. , 2004, Immunity.

[38]  R. Nusse,et al.  Convergence of Wnt, ß-Catenin, and Cadherin Pathways , 2004, Science.

[39]  A. Satoskar,et al.  Altered T helper responses in CD40 and interleukin-12 deficient mice reveal a critical role for Th1 responses in eliminating the helminth parasite Taenia crassiceps. , 2003, International journal for parasitology.

[40]  P. De Baetselier,et al.  Nitric Oxide-Independent CTL Suppression during Tumor Progression: Association with Arginase-Producing (M2) Myeloid Cells1 , 2003, The Journal of Immunology.

[41]  A. Satoskar,et al.  Macrophage Migration Inhibitory Factor Plays a Critical Role in Mediating Protection against the Helminth Parasite Taenia crassiceps , 2003, Infection and Immunity.

[42]  A. Satoskar,et al.  Cutting Edge: Susceptibility to the Larval Stage of the Helminth Parasite Taenia crassiceps Is Mediated by Th2 Response Induced Via STAT6 Signaling1 , 2002, The Journal of Immunology.

[43]  P. De Baetselier,et al.  Relative contribution of interferon-gamma and interleukin-10 to resistance to murine African trypanosomosis. , 2001, The Journal of infectious diseases.

[44]  H. Karasuyama,et al.  The Identification of a Nonclassical Cadherin Expressed during B Cell Development and Its Interaction with Surrogate Light Chain* , 2000, The Journal of Biological Chemistry.

[45]  W. Reith,et al.  Conditional gene targeting in macrophages and granulocytes using LysMcre mice , 1999, Transgenic Research.

[46]  A. Sher,et al.  Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. , 1999, Journal of immunology.

[47]  B. Malissen,et al.  Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme. , 2010, Gastroenterology.

[48]  F. Brombacher,et al.  Reactive Oxygen Species and 12/15-Lipoxygenase Contribute to the Antiproliferative Capacity of Alternatively Activated Myeloid Cells Elicited during Helminth Infection , 2005 .

[49]  R. Nusse,et al.  Convergence of Wnt, beta-catenin, and cadherin pathways. , 2004, Science.

[50]  A. Bosserhoff,et al.  Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma. , 2004, Oncogene.