Interleukin-7 Receptor Signaling Network: An Integrated Systems Perspective

[1]  A. Singer,et al.  'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR , 2007, Nature Immunology.

[2]  B. Hinz,et al.  Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells , 2007, Nature Immunology.

[3]  Silke Schmidt,et al.  Interleukin 7 receptor α chain ( IL7R ) shows allelic and functional association with multiple sclerosis , 2007, Nature Genetics.

[4]  Yong‐jun Liu,et al.  Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation. , 2007, The Journal of allergy and clinical immunology.

[5]  D. Levy,et al.  JAK-STAT Signaling: From Interferons to Cytokines* , 2007, Journal of Biological Chemistry.

[6]  I. Alexander,et al.  Limiting {gamma}c expression differentially affects signaling via the interleukin (IL)-7 and IL-15 receptors. , 2007, Blood.

[7]  Masato Kubo,et al.  SOCS proteins, cytokine signalling and immune regulation , 2007, Nature Reviews Immunology.

[8]  Tomoki Ito,et al.  TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. , 2007, Annual review of immunology.

[9]  R. Mazzucchelli,et al.  Interleukin-7 receptor expression: intelligent design , 2007, Nature Reviews Immunology.

[10]  J. Bijlsma,et al.  Persistence of interleukin 7 activity and levels on tumour necrosis factor α blockade in patients with rheumatoid arthritis , 2006, Annals of the rheumatic diseases.

[11]  M. McVey,et al.  Interleukin-7 Receptor Expression on CD8 T-Cells Is Downregulated by the HIV Tat Protein , 2006, Journal of acquired immune deficiency syndromes.

[12]  T. Gingeras,et al.  CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells , 2006, The Journal of experimental medicine.

[13]  S. Ziegler,et al.  Thymic stromal lymphopoietin in normal and pathogenic T cell development and function , 2006, Nature Immunology.

[14]  T. Gingeras,et al.  HIV regulation of the IL‐7R: a viral mechanism for enhancing HIV‐1 replication in human macrophages in vitro , 2006, Journal of leukocyte biology.

[15]  S. Rosenberg,et al.  IL-7 Administration to Humans Leads to Expansion of CD8+ and CD4+ Cells but a Relative Decrease of CD4+ T-Regulatory Cells , 2006, Journal of immunotherapy.

[16]  Yong‐jun Liu,et al.  Thymic stromal lymphopoietin: master switch for allergic inflammation , 2006, The Journal of experimental medicine.

[17]  A. Singer,et al.  Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection , 2006, The Journal of experimental medicine.

[18]  J. Thorner,et al.  Systems biology approaches in cell signaling research , 2005, Genome Biology.

[19]  Horst Vogel,et al.  CD8 kinetically promotes ligand binding to the T-cell antigen receptor. , 2005, Biophysical journal.

[20]  Yu Wang,et al.  Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus , 2005, Nature.

[21]  Q. Jiang,et al.  Cell biology of IL-7, a key lymphotrophin. , 2005, Cytokine & growth factor reviews.

[22]  J. Sprent,et al.  Regulation of mature T cell homeostasis. , 2005, Seminars in immunology.

[23]  T. Fry,et al.  The Many Faces of IL-7: From Lymphopoiesis to Peripheral T Cell Maintenance , 2005, The Journal of Immunology.

[24]  Harinder Singh,et al.  Genetic networks that regulate B lymphopoiesis , 2005, Current opinion in hematology.

[25]  J. Barata,et al.  Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis? , 2005, Leukemia & lymphoma.

[26]  I. Leskov,et al.  Homeostasis of T cell diversity. , 2005, Cellular & molecular immunology.

[27]  E. Wagner,et al.  Stat5 tetramer formation is associated with leukemogenesis. , 2005, Cancer cell.

[28]  Yili Yang,et al.  Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis. , 2004, Blood.

[29]  Michelle M. Sandau,et al.  Cutting Edge: Transpresentation of IL-15 by Bone Marrow-Derived Cells Necessitates Expression of IL-15 and IL-15Rα by the Same Cells1 , 2004, The Journal of Immunology.

[30]  A. Singer,et al.  Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. , 2004, Immunity.

[31]  H. Young,et al.  Distinct Regions of the Interleukin-7 Receptor Regulate Different Bcl2 Family Members , 2004, Molecular and Cellular Biology.

[32]  S. Ho,et al.  Human thymic stromal lymphopoietin promotes dendritic cell–mediated CD4+ T cell homeostatic expansion , 2004, Nature Immunology.

[33]  M. Busslinger.  Transcriptional control of early B cell development. , 2004, Annual review of immunology.

[34]  L. Staudt,et al.  Analysis of γc-Family Cytokine Target Genes , 2003, The Journal of Biological Chemistry.

[35]  W. Leonard,et al.  Cytokine and Cytokine Receptor Pleiotropy and Redundancy* , 2002, The Journal of Biological Chemistry.

[36]  Lewis C Cantley,et al.  The phosphoinositide 3-kinase pathway. , 2002, Science.

[37]  Y. Li,et al.  IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[38]  C. Murre,et al.  E protein function in lymphocyte development. , 2002, Annual review of immunology.

[39]  Rustom Antia,et al.  Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells , 2002, The Journal of experimental medicine.

[40]  W. Leonard.  Cytokines and immunodeficiency diseases , 2001, Nature Reviews Immunology.

[41]  R. de Waal Malefyt,et al.  Human Thymic Stromal Lymphopoietin Preferentially Stimulates Myeloid Cells1 , 2001, The Journal of Immunology.

[42]  I. Williams,et al.  Cutaneous interleukin‐7 transgenic mice display a propitious environment to Schistosoma mansoni infection , 2001, Parasite immunology.

[43]  Heinz Baumann,et al.  Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin , 2000, Nature Immunology.

[44]  S. Moro,et al.  DNA Binding Site Selection of Dimeric and Tetrameric Stat5 Proteins Reveals a Large Repertoire of Divergent Tetrameric Stat5a Binding Sites , 2000, Molecular and Cellular Biology.

[45]  S. Ziegler,et al.  Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction. , 1999, Journal of immunology.

[46]  A. Yoshimura,et al.  SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality , 1999, Cell.

[47]  B. Foxwell,et al.  Association of the common gamma-chain with the human IL-7 receptor is modulated by T cell activation. , 1997, Journal of immunology.

[48]  B. Nelson,et al.  The IL-4 receptor alpha-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4-specific gene expression. , 1997, Journal of immunology.

[49]  Philip R. Kuhl,et al.  Tethered epidermal growth factor as a paradigm for growth factor–induced stimulation from the solid phase , 1996, Nature Medicine.

[50]  W. Leonard,et al.  The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. , 1995, Immunity.

[51]  S. Burdach,et al.  Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine , 1995, The Journal of experimental medicine.

[52]  J. Gribben,et al.  Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor. , 1994, Science.

[53]  C. Ware,et al.  Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice , 1994, The Journal of experimental medicine.

[54]  A. Venkitaraman,et al.  Interleukin‐7 induces the association of phosphatidylinositol 3‐kinase with the α chain of the interleukin‐7 receptor , 1994, European journal of immunology.

[55]  D. Cosman,et al.  Utilization of the beta and gamma chains of the IL‐2 receptor by the novel cytokine IL‐15. , 1994, The EMBO journal.