Specific region affects the difference in accumulation levels between apple food allergen Mal d 1 and birch pollen allergen Bet v 1 which are expressed in vegetative tissues of transgenic rice

[1]  Taiji Kawakatsu,et al.  An overview on the strategies to exploit rice endosperm as production platform for biopharmaceuticals. , 2017, Plant science : an international journal of experimental plant biology.

[2]  R. Menassa,et al.  Protein bodies: how the ER deals with high accumulation of recombinant proteins , 2017, Plant biotechnology journal.

[3]  M. Tollinger,et al.  Structure of the Major Apple Allergen Mal d 1 , 2017, Journal of agricultural and food chemistry.

[4]  N. Maruyama,et al.  Deposition mode of transforming growth factor-β expressed in transgenic rice seed , 2016, Plant Cell Reports.

[5]  F. Takaiwa,et al.  Rice seed for delivery of vaccines to gut mucosal immune tissues. , 2015, Plant biotechnology journal.

[6]  A. Conley,et al.  Protein body formation in leaves of Nicotiana benthamiana: a concentration-dependent mechanism influenced by the presence of fusion tags. , 2015, Plant biotechnology journal.

[7]  Hideyuki Takahashi,et al.  Generation mechanism of novel, huge protein bodies containing wild type or hypoallergenic derivatives of birch pollen allergen Bet v 1 in rice endosperm , 2014, Plant Molecular Biology.

[8]  P. Agarwal,et al.  Pathogenesis related-10 proteins are small, structurally similar but with diverse role in stress signaling , 2013, Molecular Biology Reports.

[9]  P. Lackner,et al.  Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis , 2013, Allergy.

[10]  E. Stoger,et al.  Subcellular accumulation and modification of pharmaceutical proteins in different plant tissues. , 2013, Current pharmaceutical design.

[11]  Hideyuki Takahashi,et al.  Transgenic rice seeds accumulating recombinant hypoallergenic birch pollen allergen Bet v 1 generate giant protein bodies. , 2013, Plant & cell physiology.

[12]  Rima Menassa,et al.  Protein body formation in stable transgenic tobacco expressing elastin-like polypeptide and hydrophobin fusion proteins , 2013, BMC Biotechnology.

[13]  G. Pagliarani,et al.  A qRT-PCR assay for the expression of all Mal d 1 isoallergen genes , 2013, BMC Plant Biology.

[14]  M. Jaskólski,et al.  Structural and functional aspects of PR‐10 proteins , 2013, The FEBS journal.

[15]  T. Masumura,et al.  Accumulation of rice prolamin–GFP fusion proteins induces ER-derived protein bodies in transgenic rice calli , 2013, Plant Cell Reports.

[16]  F. Takaiwa Update on the use of transgenic rice seeds in oral immunotherapy. , 2013, Immunotherapy.

[17]  F. Takaiwa,et al.  Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice , 2012, Planta.

[18]  J. Howard,et al.  Overproduction of recombinant proteins in plants. , 2012, Plant science : an international journal of experimental plant biology.

[19]  A. Conley,et al.  Protein body-inducing fusions for high-level production and purification of recombinant proteins in plants. , 2011, Plant biotechnology journal.

[20]  M. Gajhede,et al.  Epitope Grafting, Re-creating a Conformational Bet v 1 Antibody Epitope on the Surface of the Homologous Apple Allergen Mal d 1 , 2011, The Journal of Biological Chemistry.

[21]  Hideyuki Takahashi,et al.  Expression of ER quality control-related genes in response to changes in BiP1 levels in developing rice endosperm. , 2011, The Plant journal : for cell and molecular biology.

[22]  J. Lidholm,et al.  Birch pollen-related food allergy: clinical aspects and the role of allergen-specific IgE and IgG4 antibodies. , 2011, The Journal of allergy and clinical immunology.

[23]  David Holding,et al.  Delivery of Prolamins to the Protein Storage Vacuole in Maize Aleurone Cells[W] , 2011, Plant Cell.

[24]  Youko Oono,et al.  Analysis of ER stress in developing rice endosperm accumulating beta-amyloid peptide. , 2010, Plant biotechnology journal.

[25]  T. Haahtela,et al.  Transient Dimers of Allergens , 2010, PloS one.

[26]  A. Matthes,et al.  Apple (Malus domestica L. Borkh.) allergen Mal d 1: effect of cultivar, cultivation system, and storage conditions. , 2009, Journal of agricultural and food chemistry.

[27]  H. Yasuda,et al.  Overexpression of BiP has inhibitory effects on the accumulation of seed storage proteins in endosperm cells of rice. , 2009, Plant & cell physiology.

[28]  S. Hirose,et al.  Deposition of a recombinant peptide in ER-derived protein bodies by retention with cysteine-rich prolamins in transgenic rice seed , 2009, Planta.

[29]  Hideyuki Takahashi,et al.  A green fluorescent protein fused to rice prolamin forms protein body-like structures in transgenic rice , 2009, Journal of experimental botany.

[30]  V. Gomord,et al.  Preventing unintended proteolysis in plant protein biofactories , 2008, Plant biotechnology journal.

[31]  P. Lackner,et al.  Allergy multivaccines created by DNA shuffling of tree pollen allergens. , 2007, The Journal of allergy and clinical immunology.

[32]  H. Yasuda,et al.  High accumulation of bioactive peptide in transgenic rice seeds by expression of introduced multiple genes. , 2006, Plant biotechnology journal.

[33]  T. Jomori,et al.  The correlation between expression and localization of a foreign gene product in rice endosperm. , 2006, Plant & cell physiology.

[34]  P. Briza,et al.  Mutational Analysis of Amino Acid Positions Crucial for IgE-Binding Epitopes of the Major Apple (Malus domestica) Allergen, Mal d 1 , 2005, International Archives of Allergy and Immunology.

[35]  C. Betzel,et al.  Dimerization of the Major Birch Pollen Allergen Bet v 1 Is Important for its In Vivo IgE-Cross-Linking Potential in Mice1 , 2005, The Journal of Immunology.

[36]  G. Marzban,et al.  Localisation and distribution of the major allergens in apple fruits , 2005 .

[37]  S. Vieths,et al.  The oral allergy syndrome: improved diagnostic and treatment methods , 2005, Current opinion in allergy and clinical immunology.

[38]  P. Christou,et al.  Sowing the seeds of success: pharmaceutical proteins from plants. , 2005, Current opinion in biotechnology.

[39]  E. Macrae,et al.  Characterisation of Mal d 1-related genes in Malus , 2004, Plant Molecular Biology.

[40]  F. Takaiwa,et al.  Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice. , 2004, Plant biotechnology journal.

[41]  S. Utsumi,et al.  Foreign gene products can be enhanced by introduction into low storage protein mutants. , 2003, Plant biotechnology journal.

[42]  M. Gajhede,et al.  Dominating IgE-Binding Epitope of Bet v 1, the Major Allergen of Birch Pollen, Characterized by X-ray Crystallography and Site-Directed Mutagenesis , 2003, The Journal of Immunology.

[43]  M. Gajhede,et al.  Dominant Epitopes and Allergic Cross-Reactivity: Complex Formation Between a Fab Fragment of a Monoclonal Murine IgG Antibody and the Major Allergen from Birch Pollen Bet v 11 , 2000, The Journal of Immunology.

[44]  H. Katinger,et al.  The promoter of an apple Ypr10 gene, encoding the major allergen Mal d 1, is stress- and pathogen-inducible , 2000 .

[45]  S. Toki,et al.  Iron fortification of rice seed by the soybean ferritin gene , 1999, Nature Biotechnology.

[46]  H. Breiteneder,et al.  Bet v 1, the major birch pollen allergen, and Mal d 1, the major apple allergen, cross-react at the level of allergen-specific T helper cells. , 1998, The Journal of allergy and clinical immunology.

[47]  R. Valenta,et al.  Common epitopes of birch pollen and apples--studies by western and northern blot. , 1991, The Journal of allergy and clinical immunology.

[48]  P. R. Sibbald,et al.  The P-loop--a common motif in ATP- and GTP-binding proteins. , 1990, Trends in biochemical sciences.

[49]  S. Kikuchi,et al.  A rice glutelin gene family — a major type of glutelin mRNAs can be divided into two classes , 1987, Molecular and General Genetics MGG.

[50]  H. Kiyono,et al.  RNAi-mediated suppression of endogenous storage proteins leads to a change in localization of overexpressed cholera toxin B-subunit and the allergen protein RAG2 in rice seeds , 2013, Plant Cell Reports.

[51]  S. Hirose,et al.  Endosperm tissue is good production platform for artificial recombinant proteins in transgenic rice. , 2007, Plant biotechnology journal.

[52]  Jun-jun Liu,et al.  The family 10 of plant pathogenesis-related proteins: Their structure, regulation, and function in response to biotic and abiotic stresses , 2006 .