Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis.
暂无分享,去创建一个
B. Simons | D. Polk | Cambrian Y. Liu | Martin Kalski | Nandini Girish | Jessica K. Bernard | Marie L. Gomez
[1] M. Washington,et al. Transitional anal cells mediate colonic re-epithelialization in colitis. , 2022, Gastroenterology.
[2] M. Colonna,et al. Adaptive differentiation promotes intestinal villus recovery. , 2022, Developmental cell.
[3] M. Washington,et al. Persistence of Lgr5+ colonic epithelial stem cells in mouse models of inflammatory bowel disease. , 2021, American journal of physiology. Gastrointestinal and liver physiology.
[4] C. Cham,et al. Epithelial wound healing in inflammatory bowel diseases: the next therapeutic frontier. , 2021, Translational research : the journal of laboratory and clinical medicine.
[5] D. Stange,et al. Tracing oncogene-driven remodelling of the intestinal stem cell niche , 2021, Nature.
[6] Maria C. Lecca,et al. Apc-mutant cells act as supercompetitors in intestinal tumour initiation , 2021, Nature.
[7] H. Clevers,et al. NOTUM from Apc-mutant cells biases clonal competition to initiate cancer , 2021, Nature.
[8] S. Smirnov,et al. Critical role of interferons in gastrointestinal injury repair , 2021, Nature Communications.
[9] S. Ogawa,et al. Clonal expansion in non-cancer tissues , 2021, Nature Reviews Cancer.
[10] H. Clevers,et al. Tissue regeneration: Reserve or reverse? , 2021, Science.
[11] M. Washington,et al. TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice , 2020, Cell reports.
[12] Cambrian Yangshao Liu,et al. Cellular maps of gastrointestinal organs: getting the most from tissue clearing. , 2020, American journal of physiology. Gastrointestinal and liver physiology.
[13] H. Clevers,et al. Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. , 2020, Cell stem cell.
[14] H. Ikeuchi,et al. Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis , 2019, Nature.
[15] T. Hibi,et al. Somatic inflammatory gene mutations in human ulcerative colitis epithelium , 2019, Nature.
[16] M. Parkes,et al. Somatic Evolution in Non-neoplastic IBD-Affected Colon , 2020, Cell.
[17] L. Sibley,et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells , 2019, Cell.
[18] Aviv Regev,et al. Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis , 2019, Cell.
[19] Markus Rempfler,et al. Self-organization and symmetry breaking in intestinal organoid development , 2019, Nature.
[20] Kin F. Chan,et al. Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell , 2019, Nature.
[21] Andrew J. Hill,et al. The single cell transcriptional landscape of mammalian organogenesis , 2019, Nature.
[22] O. Klein,et al. Parasitic helminthes induce fetal-like reversion in the intestinal stem cell niche , 2018, Nature.
[23] M. Washington,et al. Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice , 2018, Scientific Reports.
[24] Laleh Haghverdi,et al. Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors , 2018, Nature Biotechnology.
[25] O. Nielsen,et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration , 2018, Cell stem cell.
[26] A. Sepulveda,et al. Transitional basal cells at the squamous-columnar junction generate Barrett’s oesophagus , 2017, Nature.
[27] Alexander van Oudenaarden,et al. Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters. , 2016, Cell stem cell.
[28] D. Polk,et al. Innovative and Emerging Technologies in GI Physiology and Disease Optical reconstruction of murine colorectal mucosa at cellular resolution , 2015 .
[29] N. Renier,et al. iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging , 2014, Cell.
[30] D. Chang,et al. Colorectal cancer in inflammatory bowel disease: the risk, pathogenesis, prevention and diagnosis. , 2014, World journal of gastroenterology.
[31] S. Xiao,et al. Histological evaluation in ulcerative colitis , 2014, Gastroenterology report.
[32] F. D. de Sauvage,et al. Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration. , 2014, Cell stem cell.
[33] H. Clevers,et al. Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion , 2013, EMBO reports.
[34] Andrea Sottoriva,et al. Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation , 2013, Science.
[35] Simon Tavaré,et al. Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas. , 2013, Cell stem cell.
[36] Gabriela Vasile,et al. Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. , 2013, Cell reports.
[37] E. Chen,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[38] Terry P Yamaguchi,et al. Wnt5a Potentiates TGF-β Signaling to Promote Colonic Crypt Regeneration After Tissue Injury , 2012, Science.
[39] N. Barker,et al. Alteration of colonic stem cell gene signatures during the regenerative response to injury. , 2012, Biochimica et Biophysica Acta.
[40] H. Lester,et al. Electrophysiological characterization of Grueneberg ganglion olfactory neurons: spontaneous firing, sodium conductance, and hyperpolarization-activated currents. , 2012, Journal of neurophysiology.
[41] Johannes E. Schindelin,et al. Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.
[42] T. Graham,et al. Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis. , 2012, Gastroenterology.
[43] Bruce J. Aronow,et al. The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor , 2012, Cell.
[44] Steven L Salzberg,et al. Fast gapped-read alignment with Bowtie 2 , 2012, Nature Methods.
[45] Heng Li,et al. A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data , 2011, Bioinform..
[46] O. Klein,et al. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable , 2011, Nature.
[47] Allon M. Klein,et al. Universal patterns of stem cell fate in cycling adult tissues , 2011, Development.
[48] Allon M Klein,et al. Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift , 2010, Science.
[49] Hans Clevers,et al. Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells , 2010, Cell.
[50] Allan R. Jones,et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain , 2009, Nature Neuroscience.
[51] M. Bronner,et al. Clonal expansions in ulcerative colitis identify patients with neoplasia , 2009, Proceedings of the National Academy of Sciences.
[52] Gonçalo R. Abecasis,et al. The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..
[53] N. Shepherd,et al. Clonality, founder mutations, and field cancerization in human ulcerative colitis-associated neoplasia. , 2009, Gastroenterology.
[54] Sarah L. Brown,et al. Efficient colonic mucosal wound repair requires Trem2 signaling , 2009, Proceedings of the National Academy of Sciences.
[55] D. Koller,et al. The Immunological Genome Project: networks of gene expression in immune cells , 2008, Nature Immunology.
[56] M. Capecchi,et al. Bmi1 is expressed in vivo in intestinal stem cells , 2008, Nature Genetics.
[57] Jamie A Davies,et al. GUDMAP: the genitourinary developmental molecular anatomy project. , 2008, Journal of the American Society of Nephrology : JASN.
[58] H. Clevers,et al. Identification of stem cells in small intestine and colon by marker gene Lgr5 , 2007, Nature.
[59] L. Luo,et al. A global double‐fluorescent Cre reporter mouse , 2007, Genesis.
[60] A. Hopkins,et al. Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors. , 2007, American journal of physiology. Gastrointestinal and liver physiology.
[61] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[62] Daniel Metzger,et al. Tissue‐specific and inducible Cre‐mediated recombination in the gut epithelium , 2004, Genesis.
[63] C. R. Leemans,et al. A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications. , 2003, Cancer research.
[64] C. Fenoglio-Preiser,et al. Multifocal neoplasia involving the colon and appendix in ulcerative colitis: pathological and molecular features. , 1998, Gastroenterology.
[65] D. Podolsky,et al. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta. , 1993, Gastroenterology.
[66] D. Slaughter,et al. “Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin , 1953, Cancer.
[67] M. Frey,et al. Mucosal Restitution and Repair , 2012 .
[68] R. Xavier,et al. Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells. , 2003, The American journal of pathology.