RESPIRATORY METABOLISM IN INFANCY AND IN CHILDHOOD: XVI. EFFECT OF INTRAVENOUS INFUSIONS OF FAT ON THE ENERGY EXCHANGE OF INFANTS

The parenteral administration of fat as a potential source of energy has long appealed to clinical investigators. Evidence of the availability to the organism of fat so administered has for the most part been adduced by indirect methods of approach. Such studies include: chemical analyses of the blood; chemical and histologic examination of the sites of injection, regional lymph nodes and various viscera following parenteral administration of fat; studies of nitrogen balance; studies of absorption and excretion of fat-soluble drugs and dyes; observations on the utilization of fat-soluble vitamins, and finally clinical records of the response of malnourished persons to repeated injections of fat. The results secured from these indirect lines of investigation are far from conclusive, but they suggest that some preparations may be utilized by the organism under certain conditions. The literature covering these studies, which has accumulated since the experiments of von Leube1in 1895, was

[1]  L. E. Holt,et al.  The intravenous administration of fat , 1935 .

[2]  J. Murlin,et al.  The Possibility of Gluconeogenesis from Fat II. The Effect of High Fat Diets on the Respiratory Metabolism and Ketosis of Man , 1933 .

[3]  D. E. Gregg.  THE CALORIGENIC ACTION OF LECITHIN , 1932 .

[4]  Toji. Baba.  Über den Abbau direkt infundierten Fetts im Tierkörper , 1931 .

[5]  Seinosuke Hotta.  Zur Frage der Resorption parenteral eingeführten emulgierten Fetts , 1930 .

[6]  Toshiharu Nomura,et al.  Zur Frage der Resorption des emulgierten Fetts vom Dickdarm aus , 1929 .

[7]  Masakichi Kimura.  Experimentelle Studien über intravenöse Fettinfusion unter besonderer Berücksichtigung parenteraler Ernährung , 1929 .

[8]  Toshiharu Nomura.  Experimentelle Studien über intravenöse Fettinfusion unter besonderer Berücksichtigung parenteraler Ernährung , 1929 .

[9]  S. Z. Levine,et al.  THE RESPIRATORY METABOLISM IN INFANCY AND IN CHILDHOOD: X. THE RESPIRATORY EXCHANGE IN MARASMUS: SPECIFIC DYNAMIC ACTION OF FOOD IN NORMAL AND IN MARASMIC INFANTS , 1928 .

[10]  S. Z. Levine,et al.  THE RESPIRATORY METABOLISM IN INFANCY AND IN CHILDHOOD: VI. THE SPECIFIC DYNAMIC ACTION OF FOOD IN NORMAL INFANTS , 1927 .

[11]  S. Z. Levine,et al.  THE RESPIRATORY METABOLISM IN INFANCY AND IN CHILDHOOD: II. KETOSIS AND THE RESPIRATORY EXCHANGE IN CHILDREN , 1926 .

[12]  S. Z. Levine,et al.  THE RESPIRATORY METABOLISM IN INFANCY AND IN CHILDHOOD: I. BASAL METABOLISM OF CHILDREN , 1926 .

[13]  G. Lusk,et al.  ANIMAL CALORIMETRY Twenty-Fourth Paper. ANALYSIS OF THE OXIDATION OF MIXTURES OF CARBOHYDRATE AND FAT , 1924 .

[14]  J. Riche,et al.  Blood fat in relation to heat production and depth of narcosis , 1915 .

[15]  G. Lusk,et al.  ANIMAL CALORIMETRY TWELFTH PAPER. THE INFLUENCE OF THE INGESTION OF FAT , 1915 .

[16]  L. Mills.  THE UTILIZATION OF FATS AND OILS GIVEN SUBCUTANEOUSLY , 1911 .

[17]  G. Lusk.  The specific dynamic action. , 1931 .

[18]  N. Zuntz,et al.  Studien zu einer Physiologie des Marsches , 1901 .