Carbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment
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T. Soga | M. Morimoto | N. Shinohara | H. Kikuchi | Y. Hida | N. Maishi | D. A. Annan | Takayuki Hojo | K. Hida | T. Kitamura | K. Minowa | M. T. Alam | Cong Li | Jin-Min Nam | Randa Dawood
[1] H. Lane,et al. Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells , 2018, Cell reports.
[2] Sean P. Palecek,et al. Abstract 3481: Elucidating the metabolic crosstalk between lymphatic endothelial cells and breast cancer using 1H NMR metabolomics , 2018, Molecular and Cellular Biology / Genetics.
[3] S. Pastoreková,et al. The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells , 2018, Oncotarget.
[4] J. Deitmer,et al. A surface proton antenna in carbonic anhydrase II supports lactate transport in cancer cells , 2018, eLife.
[5] C. Supuran. Carbonic Anhydrases and Metabolism , 2018, Metabolites.
[6] Sufen Li,et al. COX-2 inhibition in the endothelium induces glucose metabolism normalization and impairs tumor progression , 2017, Molecular medicine reports.
[7] O. Werz,et al. Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition[S] , 2017, Journal of Lipid Research.
[8] Shaghayegh Haghjooy Javanmard,et al. Acquired tumor resistance to antiangiogenic therapy: Mechanisms at a glance , 2017, Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences.
[9] Soon-Sun Hong,et al. Tumor vessel normalization by the PI3K inhibitor HS-173 enhances drug delivery. , 2017, Cancer letters.
[10] M. Shindoh,et al. ROS enhance angiogenic properties via regulation of NRF2 in tumor endothelial cells , 2017, Oncotarget.
[11] P. Carmeliet,et al. Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy. , 2016, Cancer cell.
[12] N. Demartines,et al. Acidic pH reduces VEGF-mediated endothelial cell responses by downregulation of VEGFR-2; relevance for anti-angiogenic therapies , 2016, Oncotarget.
[13] C. Supuran,et al. Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. , 2016, Bioorganic & medicinal chemistry.
[14] Y. Ohba,et al. Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan , 2016, Scientific Reports.
[15] Yasuo Iwadate,et al. Epithelial-mesenchymal transition in glioblastoma progression , 2016, Oncology letters.
[16] Paweena Dana,et al. Inhibition of carbonic anhydrase potentiates bevacizumab treatment in cholangiocarcinoma , 2016, Tumor Biology.
[17] N. Lu,et al. Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor , 2015, Oncotarget.
[18] J. Mi,et al. Metabolic reprogramming of cancer-associated fibroblasts by IDH3α downregulation. , 2015, Cell reports.
[19] H. Yeger,et al. Carbonic anhydrase II mediates malignant behavior of pulmonary neuroendocrine tumors. , 2015, American journal of respiratory cell and molecular biology.
[20] G. Cline,et al. Functional polarization of tumour-associated macrophages by tumour-derived lactic acid , 2014, Nature.
[21] Hao Wu,et al. Beyond Warburg effect – dual metabolic nature of cancer cells , 2014, Scientific Reports.
[22] Robert J. Gillies,et al. pH sensing and regulation in cancer , 2013, Front. Physiol..
[23] N. Shinohara,et al. Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis , 2013, British Journal of Cancer.
[24] John L Cleveland,et al. Targeting lactate metabolism for cancer therapeutics. , 2013, Journal of Clinical Investigation.
[25] Mohammad Wahid Ansari,et al. The legal status of in vitro embryos , 2014 .
[26] Xun Hu,et al. Central role of lactic acidosis in cancer cell resistance to glucose deprivation‐induced cell death , 2012, The Journal of pathology.
[27] M. Dewhirst,et al. Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis , 2012, PloS one.
[28] N. Shinohara,et al. Heterogeneity of tumor endothelial cells: comparison between tumor endothelial cells isolated from high- and low-metastatic tumors. , 2012, The American journal of pathology.
[29] N. Inoue,et al. Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment. , 2012, The American journal of pathology.
[30] M. Toi,et al. Tumor Angiogenesis: Pericytes and Maturation Are Not to Be Ignored , 2011, Journal of oncology.
[31] Pierre Sonveaux,et al. Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis. , 2011, Cancer research.
[32] A. Raza,et al. Pericytes and vessel maturation during tumor angiogenesis and metastasis , 2010, American journal of hematology.
[33] Y. Totsuka,et al. Inhibitory effects of epigallocatechin‐3 gallate, a polyphenol in green tea, on tumor‐associated endothelial cells and endothelial progenitor cells , 2009, Cancer science.
[34] J. Pastorek,et al. Carbonic anhydrases in meningiomas: association of endothelial carbonic anhydrase II with aggressive tumor features. , 2009, Journal of neurosurgery.
[35] K. Ballmer-Hofer,et al. Structure and function of VEGF receptors , 2009, IUBMB life.
[36] M. Tomita,et al. Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. , 2009, Cancer research.
[37] L. Cantley,et al. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.
[38] Julien Verrax,et al. Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. , 2008, The Journal of clinical investigation.
[39] Gabriele Bergers,et al. Modes of resistance to anti-angiogenic therapy , 2008, Nature Reviews Cancer.
[40] H. Haapasalo,et al. Carbonic anhydrase II in the endothelium of glial tumors: a potential target for therapy. , 2007, Neuro-oncology.
[41] Gregor Rothe,et al. Inhibitory effect of tumor cell-derived lactic acid on human T cells. , 2007, Blood.
[42] M. O. oude Egbrink,et al. Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications. , 2006, Cancer research.
[43] G. Albertini,et al. Carbonic Anhydrase II in the Developing and Adult Human Brain , 2006, Journal of neuropathology and experimental neurology.
[44] Katsuaki Sato,et al. Carbonic Anhydrase II Is a Tumor Vessel Endothelium–Associated Antigen Targeted by Dendritic Cell Therapy , 2005, Clinical Cancer Research.
[45] Dhara N. Amin,et al. Tumor-Associated Endothelial Cells with Cytogenetic Abnormalities , 2004, Cancer Research.
[46] E. Voest,et al. Are tumours angiogenesis‐dependent? , 2004, The Journal of pathology.
[47] E. Piek,et al. Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. , 2003, Developmental biology.
[48] B. Alvarez,et al. Carbonic Anhydrase II Binds to and Enhances Activity of the Na+/H+ Exchanger* , 2002, The Journal of Biological Chemistry.
[49] R. Jain,et al. Acidic Extracellular pH Induces Vascular Endothelial Growth Factor (VEGF) in Human Glioblastoma Cells via ERK1/2 MAPK Signaling Pathway , 2002, The Journal of Biological Chemistry.
[50] F. Facchiano,et al. Acidosis inhibits endothelial cell apoptosis and function and induces basic fibroblast growth factor and vascular endothelial growth factor expression. , 2000, Circulation research.
[51] N. Price,et al. The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. , 1999, The Biochemical journal.
[52] T. Teramoto. The effect of extracellular pH on the adherence and differentiation of isolated rat osteoclasts , 1998 .
[53] Atsushi Namiki,et al. Hypoxia Induces Vascular Endothelial Growth Factor in Cultured Human Endothelial Cells (*) , 1995, The Journal of Biological Chemistry.
[54] S. Parkkila,et al. Immunohistochemical demonstration of human carbonic anhydrase isoenzyme II in brain tumours , 1995, The Histochemical Journal.
[55] K. Jennbacken,et al. Pericyte coverage decreases invasion of tumour cells into blood vessels in prostate cancer xenografts , 2009, Prostate Cancer and Prostatic Diseases.
[56] D. West,et al. The effect of extracellular pH on angiogenesis in vitro , 2004, Angiogenesis.
[57] S. Parkkila,et al. Immunohistochemical demonstration of human carbonic anhydrase isoenzyme II in brain tumours , 2004, The Histochemical Journal.
[58] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..