Quantitative evaluation of nonrepetitive phase‐encoding orders for first‐pass, 3D contrast‐enhanced MR angiography

In this work, a detailed quantitative comparison was made of many alternative phase‐encoding strategies for first‐pass 3D MR angiography where each phase encode is only sampled once during the transient passage of contrast agent. A series of standard sequential and centric phase‐encoding orders including elliptical centric were tested, as well as a new order called elliptical sequential. The characteristics of the different phase‐encoding orders were tested using a computer simulation followed by experimental verification using a variable flip angle scheme. The characteristics to be considered included: arterial intensity, arterial‐to‐venous contrast, degree of artifact, and the blurring of the point‐spread function. By making use of a wide range of start times and a rapidly varying contrast curve, the quantitative results clearly indicate the widely varying merits of each phase‐encoding order. In general, when an optimal start time is used techniques that sample the low k‐space views most compactly will produce the best results; however, the same methods are more problematic when the bolus arrival time deviates substantially from that expected. Magn Reson Med 46:541–547, 2001. © 2001 Wiley‐Liss, Inc.

[1]  S J Riederer,et al.  Theoretical limits of spatial resolution in elliptical‐centric contrast‐enhanced 3D‐MRA , 1999, Magnetic resonance in medicine.

[2]  R F Busse,et al.  Carotid arteries: maximizing arterial to venous contrast in fluoroscopically triggered contrast-enhanced MR angiography with elliptic centric view ordering. , 1999, Radiology.

[3]  Richard Frayne,et al.  3D Time‐resolved contrast‐enhanced MR DSA: Advantages and tradeoffs , 1998, Magnetic resonance in medicine.

[4]  S J Riederer,et al.  Performance of an elliptical centric view order for signal enhancement and motion artifact suppression in breath‐hold three‐dimensional gradient echo imaging , 1997, Magnetic resonance in medicine.

[5]  J. Mugler,et al.  Shaping the Signal Response during the Approach to Steady State in Three‐Dimensional Magnetization‐Prepared Rapid Gradient‐Echo Imaging Using Variable Flip Angles , 1992, Magnetic resonance in medicine.

[6]  H. Bosmans,et al.  Breath-hold contrast-enhanced three-dimensional MR angiography of the abdomen: time-resolved imaging versus single-phase imaging. , 2000, Radiology.

[7]  T. Chenevert,et al.  Automated detection of bolus arrival and initiation of data acquisition in fast, three-dimensional, gadolinium-enhanced MR angiography. , 1997, Radiology.

[8]  J. Svensson,et al.  Image artifacts due to a time‐varying contrast medium concentration in 3D contrast‐enhanced MRA , 1999, Journal of magnetic resonance imaging : JMRI.

[9]  T L Chenevert,et al.  The effects of time varying intravascular signal intensity and k‐space acquisition order on three‐dimensional MR angiography image quality , 1996, Journal of magnetic resonance imaging : JMRI.

[10]  N M Rofsky,et al.  Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography: usefulness of a timing examination and MR power injector. , 1996, Radiology.

[11]  R L Ehman,et al.  Altered phase‐encoding order for reduced sensitivity to motion in three‐dimensional MR imaging , 1992, Journal of magnetic resonance imaging : JMRI.

[12]  T. Chenevert,et al.  Breath-hold gadolinium-enhanced MR angiography of the abdominal aorta and its major branches. , 1995, Radiology.

[13]  K-space filter effect in three-dimensional contrast MR angiography , 1997, Acta radiologica.

[14]  S J Riederer,et al.  Fluoroscopically triggered contrast-enhanced three-dimensional MR angiography with elliptical centric view order: application to the renal arteries. , 1997, Radiology.

[15]  R Frayne,et al.  Time‐resolved contrast‐enhanced 3D MR angiography , 1996, Magnetic resonance in medicine.

[16]  J. Debbins,et al.  Arterial phase carotid and vertebral artery imaging in 3D contrast‐enhanced MR angiography by combining fluoroscopic triggering with an elliptical centric acquisition order , 1998, Magnetic resonance in medicine.

[17]  J K Kim,et al.  Test bolus examination in the carotid artery at dynamic gadolinium-enhanced MR angiography. , 1998, Radiology.