Design principles of photo‐bioreactors for cultivation of microalgae

The present hype in microalgae biotechnology has shown that the topic of photo‐bioreactors has to be revisited with respect to availability in really large scale measured in hectars footprint area, minimization of cost, auxiliary energy demand as well as maintenance and life span. This review gives an overview about present designs and the basic limiting factors which include light distribution to avoid saturation kinetics, mixing along the light gradient to make use of light/dark cycles, aeration and mass transfer along the vertical or horizontal main axis for carbon dioxide supply and oxygen removal and last but not least the energy demand necessary to fulfil these tasks. To make comparison of the performance of different designs easier, a commented list of performance parameters is given. Based on these critical points recent developments in the areas of membranes for gas transfer and optical structures for light transfer are discussed. The fundamental starting point for the optimization of photo‐bioprocesses is a detailed understanding of the interaction between the bioreactor in terms of mass and light transfer as well as the microalgae physiology in terms of light and carbon uptake kinetics and dynamics.

[1]  A. Carvalho,et al.  Microalgal Reactors: A Review of Enclosed System Designs and Performances , 2006, Biotechnology progress.

[2]  In Soo Suh,et al.  A novel double-layered photobioreactor for simultaneous Haematococcus pluvialis cell growth and astaxanthin accumulation. , 2006, Journal of biotechnology.

[3]  E. Molina Grima,et al.  Influence of power supply in the feasibility of Phaeodactylum tricornutum cultures , 2004, Biotechnology and bioengineering.

[4]  F. G. Acién,et al.  Tubular photobioreactor design for algal cultures. , 2001, Journal of biotechnology.

[5]  M. Spalding,et al.  Microalgal carbon-dioxide-concentrating mechanisms: Chlamydomonas inorganic carbon transporters. , 2007, Journal of experimental botany.

[6]  J. C. Merchuk,et al.  Modeling of photobioreactors: Application to bubble column simulation , 2003, Journal of Applied Phycology.

[7]  Olaf Kruse,et al.  The Solar Bio-fuels consortium: Developing advanced bio-fuel production systems , 2007 .

[8]  Roselló Sastre,et al.  Kopplung physiologischer und verfahrenstechnischer Parameter beim Wachstum und bei der Produktbildung der Rotalge Porphyridium purpureum , 2010 .

[9]  Sun Yingying,et al.  Effect of liquid circulation velocity and cell density on the growth ofParietochloris incisa in flat plate photobioreactors , 2005 .

[10]  U. Schmid-Staiger,et al.  A novel airlift photobioreactor with baffles for improved light utilization through the flashing light effect. , 2001, Journal of biotechnology.

[11]  F. G. Fernández,et al.  Comparative analysis of the outdoor culture of Haematococcus pluvialis in tubular and bubble column photobioreactors. , 2006, Journal of biotechnology.

[12]  Jose C. Merchuk,et al.  Fluid flow and mass transfer in a counter-current gas–liquid inclined tubes photo-bioreactor , 2007 .

[13]  René H. Wijffels,et al.  Design Process of an Area-Efficient Photobioreactor , 2008, Marine Biotechnology.

[14]  Jean-François Cornet,et al.  Design, Operation, and Modeling of a Membrane Photobioreactor to Study the Growth of the Cyanobacterium Arthrospira platensis in Space Conditions , 2008, Biotechnology progress.

[15]  Olaf Kruse,et al.  Photosynthetic biomass and H2 production by green algae: from bioengineering to bioreactor scale-up. , 2007, Physiologia plantarum.

[16]  In Soo Suh,et al.  Photobioreactor engineering: Design and performance , 2003 .

[17]  N. Kurano,et al.  Use of photoacclimation in the design of a novel photobioreactor to achieve high yields in algal mass cultivation , 2003, Journal of Applied Phycology.

[18]  D. Hall,et al.  Outdoor helical tubular photobioreactors for microalgal production: modeling of fluid-dynamics and mass transfer and assessment of biomass productivity. , 2003, Biotechnology and bioengineering.

[19]  Ladislav Nedbal,et al.  Influence of high frequency light/dark fluctuations on photosynthetic characteristics of microalgae photoacclimated to different light intensities and implications for mass algal cultivation , 1996, Journal of Applied Phycology.

[20]  Clemens Posten,et al.  Modelling of growth and product formation of Porphyridium purpureum. , 2007, Journal of biotechnology.

[21]  Masahiko Morita,et al.  Photosynthetic productivity of conical helical tubular photobioreactor incorporating Chlorella sorokiniana under field conditions. , 2002, Biotechnology and bioengineering.

[22]  Y. Chisti,et al.  Photobioreactors: light regime, mass transfer, and scaleup , 1999 .

[23]  David L. Beshears,et al.  First-generation hybrid solar lighting collector system development and operating experience , 2004, SPIE Optics + Photonics.

[24]  J. Ogbonna,et al.  Light/dark cyclic movement of algal culture (Synechocystis aquatilis) in outdoor inclined tubular photobioreactor equipped with static mixers for efficient production of biomass , 2004, Biotechnology Letters.

[25]  M. Borowitzka Commercial production of microalgae: ponds, tanks, tubes and fermenters , 1999 .

[26]  Ondřej Komárek,et al.  A photobioreactor system for precision cultivation of photoautotrophic microorganisms and for high‐content analysis of suspension dynamics , 2008, Biotechnology and bioengineering.

[27]  Yoshihiro Tsuchiya,et al.  Invention of outdoor closed type photobioreactor for microalgae , 2006 .

[28]  Emily Waltz,et al.  Biotech's green gold? , 2009, Nature Biotechnology.

[29]  Jo-Shu Chang,et al.  Phototrophic hydrogen production in photobioreactors coupled with solar-energy-excited optical fibers , 2008 .

[30]  C. Ugwu,et al.  Photobioreactors for mass cultivation of algae. , 2008, Bioresource technology.

[31]  O. Pulz,et al.  Photobioreactors: production systems for phototrophic microorganisms , 2001, Applied Microbiology and Biotechnology.

[32]  J. Ogbonna,et al.  An integrated solar and artificial light system for internal illumination of photobioreactors. , 1999, Journal of biotechnology.

[33]  M. Al-Dahhan,et al.  Analyzing and modeling of photobioreactors by combining first principles of physiology and hydrodynamics , 2004, Biotechnology and bioengineering.

[34]  Yuan-Kun Lee Microalgal mass culture systems and methods: Their limitation and potential , 2001, Journal of Applied Phycology.

[35]  Johannes Tramper,et al.  Microalgae cultivation in air-lift reactors: modeling biomass yield and growth rate as a function of mixing frequency. , 2003, Biotechnology and bioengineering.

[36]  Y. Chisti,et al.  Airlift-driven external-loop tubular photobioreactors for outdoor production of microalgae: assessment of design and performance , 2001 .

[37]  René H. Wijffels,et al.  Photosynthetic efficiency of Dunaliella tertiolecta under short light/dark cycles , 2001 .

[38]  H Saiki,et al.  Photosynthetic productivity of conical helical tubular photobioreactors incorporating Chlorella sp. under various culture medium flow conditions. , 2001, Biotechnology and bioengineering.

[39]  Jack Legrand,et al.  Swirling flow implementation in a photobioreactor for batch and continuous cultures of porphyridium cruentum , 2003, Biotechnology and bioengineering.

[40]  M. Dünne,et al.  Biomonitoring and risk assessment on earth and during exploratory missions using AquaHab , 2008 .

[41]  Yusuf Chisti,et al.  Bubble‐column and airlift photobioreactors for algal culture , 2000 .

[42]  Naohiro Yoshimoto,et al.  Dynamic discrete model of flashing light effect in photosynthesis of microalgae , 2005, Journal of Applied Phycology.

[43]  J. Doucha,et al.  Utilization of flue gas for cultivation of microalgae Chlorella sp.) in an outdoor open thin-layer photobioreactor , 2005, Journal of Applied Phycology.

[44]  L. Rodolfi,et al.  Microalgae for oil: Strain selection, induction of lipid synthesis and outdoor mass cultivation in a low‐cost photobioreactor , 2009, Biotechnology and bioengineering.

[45]  Li-Hua Cheng,et al.  Optimization of Carbon Dioxide Fixation by Chlorella vulgaris Cultivated in a Membrane-Photobioreactor , 2007 .

[46]  Ning Zou,et al.  Light-path length and population density in photoacclimation of Nannochloropsis sp. (Eustigmatophyceae) , 2000, Journal of Applied Phycology.

[47]  I. Perner-Nochta,et al.  Photoautotrophic Cell and Tissue Culture in a Tubular Photobioreactor , 2007 .

[48]  P. Carlozzi,et al.  Dilution of solar radiation through "culture" lamination in photobioreactor rows facing south-north: a way to improve the efficiency of light utilization by cyanobacteria (Arthrospira platensis). , 2003, Biotechnology and bioengineering.

[49]  F Gòdia,et al.  MELISSA: a loop of interconnected bioreactors to develop life support in space. , 2002, Journal of biotechnology.

[50]  O. Pulz,et al.  Valuable products from biotechnology of microalgae , 2004, Applied Microbiology and Biotechnology.

[51]  S. Long,et al.  What is the maximum efficiency with which photosynthesis can convert solar energy into biomass? , 2008, Current opinion in biotechnology.

[52]  Jeff D. Muhs,et al.  Economic Analysis of a Vertical Sheet Algal Photobioreactor for Biodiesel Production , 2007 .

[53]  A. Richmond,et al.  Efficient use of strong light for high photosynthetic productivity: interrelationships between the optical path, the optimal population density and cell-growth inhibition. , 2003, Biomolecular engineering.

[54]  J. C. Merchuk,et al.  Photobioreactor Design and Fluid Dynamics , 2007 .

[55]  Jean-François Cornet,et al.  Hydrodynamics influence on light conversion in photobioreactors: An energetically consistent analysis , 2008 .

[56]  Y. Chisti,et al.  Comparative evaluation of compact photobioreactors for large-scale monoculture of microalgae , 1999 .

[57]  J Tramper,et al.  Efficiency of light utilization of Chlamydomonas reinhardtii under medium-duration light/dark cycles. , 2000, Journal of biotechnology.

[58]  Johannes Tramper,et al.  Enclosed outdoor photobioreactors: light regime, photosynthetic efficiency, scale-up, and future prospects. , 2003, Biotechnology and bioengineering.

[59]  A. Lodi,et al.  Effects of carbon dioxide feeding rate and light intensity on the fed-batch pulse-feeding cultivation of Spirulina platensis in helical photobioreactor , 2008 .

[60]  D. Hall,et al.  Outdoor production of Phaeodactylum tricornutum biomass in a helical reactor. , 2003, Journal of biotechnology.

[61]  Clemens Posten,et al.  Simulations of light intensity variation in photobioreactors. , 2007, Journal of biotechnology.

[62]  Yongkang Tang,et al.  Development of a ground-based space micro-algae photo-bioreactor , 2008 .

[63]  Graziella Chini Zittelli,et al.  Productivity and photosynthetic efficiency of outdoor cultures of Tetraselmis suecica in annular columns , 2006 .

[64]  Miguel Olaizola,et al.  Commercial development of microalgal biotechnology: from the test tube to the marketplace. , 2003, Biomolecular engineering.

[65]  Ladislav Nedbal,et al.  Photosynthesis, Growth and Photoinhibition of Microalgae Exposed to Intermittent Light , 1995 .

[66]  Claude-Gilles Dussap,et al.  A simplified monodimensional approach for modeling coupling between radiant light transfer and growth kinetics in photobioreactors , 1995 .

[67]  Yoojeong Kim,et al.  Air-Lift Bioreactors for Algal Growth on Flue Gas: Mathematical Modeling and Pilot-Plant Studies , 2005 .

[68]  Z-Hun Kim,et al.  Specific Light Uptake Rate Can be Served as a Scale-Up Parameter in Photobioreactor Operations , 2006 .

[69]  Jos Malda,et al.  Hydrodynamics and mass transfer in a tubular airlift photobioreactor , 2002, Journal of Applied Phycology.

[70]  C. Whittingham,et al.  Photosynthesis , 1941, Nature.

[71]  S. Oncel,et al.  Comparison of two different pneumatically mixed column photobioreactors for the cultivation of Artrospira platensis (Spirulina platensis). , 2008, Bioresource technology.

[72]  Li-Hua Cheng,et al.  Carbon dioxide removal from air by microalgae cultured in a membrane-photobioreactor , 2006 .

[73]  Johannes Tramper,et al.  Capturing sunlight into a photobioreactor: Ray tracing simulations of the propagation of light from capture to distribution into the reactor , 2008 .

[74]  Clemens Posten,et al.  Scale-down of microalgae cultivations in tubular photo-bioreactors--a conceptual approach. , 2007, Journal of biotechnology.

[75]  A. McDowall,et al.  Engineering photosynthetic light capture: impacts on improved solar energy to biomass conversion. , 2007, Plant biotechnology journal.

[76]  F. G. Acién,et al.  Characterization of a flat plate photobioreactor for the production of microalgae , 2008 .

[77]  Y. Chisti,et al.  Scale-up of tubular photobioreactors , 2000, Journal of Applied Phycology.

[78]  Jack Legrand,et al.  Numerical investigation of hydrodynamic and mixing conditions in a torus photobioreactor , 2006 .

[79]  John R. Benemann,et al.  Dunaliella salina (Chlorophyta) with small chlorophyll antenna sizes exhibit higher photosynthetic productivities and photon use efficiencies than normally pigmented cells , 1998, Journal of Applied Phycology.

[80]  N. T. Eriksen The technology of microalgal culturing , 2008, Biotechnology Letters.

[81]  Mario R. Tredici,et al.  Mass production of microalgae: photobioreactors , 2007 .