The Role of NSAIDs in the Management of Postoperative Ophthalmic Inflammation

[1]  S. Mohr,et al.  Topical Administration of Nepafenac Inhibits Diabetes-Induced Retinal Microvascular Disease and Underlying Abnormalities of Retinal Metabolism and Physiology , 2007, Diabetes.

[2]  Satish S. Modi,et al.  Nepafenac ophthalmic suspension 0.1% for the prevention and treatment of ocular inflammation associated with cataract surgery , 2007, Journal of cataract and refractive surgery.

[3]  J. Colin,et al.  Comparison of the analgesic efficacy and safety of nepafenac ophthalmic suspension compared with diclofenac ophthalmic solution for ocular pain and photophobia after excimer laser surgery: a phase II, randomized, double-masked trial. , 2006, Clinical therapeutics.

[4]  R. Pineda,et al.  Corneal Ulceration and Perforation With Ketorolac Tromethamine (Acular®) Use After PRK , 2006, Cornea.

[5]  Y. Hotta,et al.  Three Cases of Corneal Melting After Instillation of a New Nonsteroidal Anti-Inflammatory Drug , 2006, Cornea.

[6]  Terry Kim,et al.  Ocular permeation and inhibition of retinal inflammation: an examination of data and expert opinion on the clinical utility of nepafenac , 2006 .

[7]  F. Parmeggiani,et al.  The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients. , 2005, Experimental eye research.

[8]  S. John Mechanistic insights into glaucoma provided by experimental genetics the cogan lecture. , 2005, Investigative ophthalmology & visual science.

[9]  Richard S. Smith Introducing Simon John, the 2004 Recipient of the Cogan Award , 2005 .

[10]  T. O'brien Emerging guidelines for use of NSAID therapy to optimize cataract surgery patient care , 2005, Current medical research and opinion.

[11]  J. Marshall,et al.  The effect of a selective cyclooxygenase-2 (COX-2) inhibitor on the proliferation rate of retinoblastoma cell lines , 2005, Eye.

[12]  R. Rice,et al.  Ocular Effects of Nepafenac Ophthalmic Suspension Following Six Months of Topical Ocular Administration to Pigmented Rabbits , 2005 .

[13]  R. Munger,et al.  Ocular Effects of Nepafenac Ophthalmic Suspension Following Three Months of Topical Ocular Administration to Cynomolgus Monkeys , 2005 .

[14]  F. Bucci,et al.  Comparison of Ketorolac 0.5%, Ketorolac 0.4%, and Diclofenac 0.1% – Combined With Prednisolone 0.1% on Aqueous Flare Following Cataract Surgery , 2005 .

[15]  J. Penn,et al.  Nepafenac Metabolite, Amfenac, Inhibits VEGF Induced Phosphorylation of ERK in Human Retinal Microvascular Endothelial Cells , 2005 .

[16]  D. Faingold,et al.  The Cyclooxygenase–2 Inhibitor Nepafenac Improves the Function of Macrophages Suppressed by Uveal Melanoma Conditioned Medium , 2005 .

[17]  R. Rice,et al.  Ocular Effects of Nepafenac Ophthalmic Suspension in New Zealand White Rabbits Undergoing Partial Corneal Incisions , 2005 .

[18]  F. Price,et al.  Efficacy of topical ketorolac tromethamine 0.4% for control of pain or discomfort associated with cataract surgery , 2004, Current Medical Research and Opinion.

[19]  M. Raizman,et al.  Safety and efficacy of ketorolac tromethamine 0.4% ophthalmic solution in post‐photorefractive keratectomy patients , 2004, Journal of cataract and refractive surgery.

[20]  D. S. Rho Treatment of acute pseudophakic cystoid macular edema: Diclofenac versus ketorolac , 2003, Journal of cataract and refractive surgery.

[21]  F. Afrashi,et al.  Incidence of Cystoid Macular Edema after Uncomplicated Phacoemulsification , 2003, Ophthalmologica.

[22]  J. Flanagan,et al.  Inflammation-Mediated Retinal Edema in the Rabbit Is Inhibited by Topical Nepafenac , 2003, Inflammation.

[23]  S. Koevary Pharmacokinetics of topical ocular drug delivery: potential uses for the treatment of diseases of the posterior segment and beyond. , 2003, Current drug metabolism.

[24]  T. O'brien,et al.  Effects of topical nonsteroidal antiinflammatory drugs on the expression of matrix metalloproteinases in the cornea , 2003 .

[25]  R. Schalnus Topical Nonsteroidal Anti-Inflammatory Therapy in Ophthalmology , 2003, Ophthalmologica.

[26]  A. Martidis,et al.  Managing cystoid macular edema after cataract surgery , 2003, Current opinion in ophthalmology.

[27]  P. McDonnell,et al.  Histopathology of corneal melting associated with diclofenac use after refractive surgery , 2003, Journal of cataract and refractive surgery.

[28]  K. Miyake,et al.  Prostaglandins and cystoid macular edema. , 2002, Survey of ophthalmology.

[29]  I. Udell,et al.  Keratitis, ulceration, and perforation associated with topical nonsteroidal anti-inflammatory drugs. , 2001, Ophthalmology.

[30]  F. Sauerburger,et al.  The role of matrix metalloproteinases in ulcerative keratolysis associated with perioperative diclofenac use. , 2001, Ophthalmology.

[31]  D. Fone,et al.  Randomised controlled trial of ketorolac in the management of korneal abrasions , 2001 .

[32]  N. Congdon,et al.  Corneal complications associated with topical ophthalmic use of nonsteroidal antiinflammatory drugs , 2001, Journal of cataract and refractive surgery.

[33]  K. Solomon,et al.  Topical ketorolac tromethamine 0.5% ophthalmic solution in ocular inflammation after cataract surgery. , 2001, Ophthalmology.

[34]  Flach Discussion by allan J. Flach, MD , 2000, Ophthalmology.

[35]  M. Plebani,et al.  Anti-inflammatory and antiallergic effects of ketorolac tromethamine in the conjunctival provocation model , 2000, The British journal of ophthalmology.

[36]  W. Baumann,et al.  Ketorolac versus prednisolone versus combination therapy in the treatment of acute pseudophakic cystoid macular edema. , 2000, Ophthalmology.

[37]  J. Yanni,et al.  Nepafenac, a Unique Nonsteroidal Prodrug with Potential Utility in the Treatment of Trauma-Induced Ocular Inflammation: II. In Vitro Bioactivation and Permeation of External Ocular Barriers , 2000, Inflammation.

[38]  J. Yanni,et al.  Nepafenac, a Unique Nonsteroidal Prodrug with Potential Utility in the Treatment of Trauma-Induced Ocular Inflammation: I. Assessment of Anti-Inflammatory Efficacy , 2000, Inflammation.

[39]  J. Schwiegerling,et al.  Acular as a single agent for use as an antimiotic and anti-inflammatory in cataract surgery. , 2000, Journal of cataract and refractive surgery.

[40]  M. Raizman,et al.  Efficacy and safety of ketorolac tromethamine 0.5% and levocabastine 0.05%: a multicenter comparison in patients with seasonal allergic conjunctivitis , 2000, Advances in therapy.

[41]  R. Rajpal,et al.  Analgesic Efficacy and Safety of Ketorolac After Photorefractive Keratectomy , 1999 .

[42]  N. Bressler,et al.  Ketorolac treatment of pseudophakic cystoid macular edema identified more than 24 months after cataract extraction. , 1999, Ophthalmology.

[43]  J. Jenkins,et al.  Comparison of the efficacy and safety of ketorolac tromethamine 0.5% and prednisolone acetate 1% after cataract surgery. , 1999, Journal of cataract and refractive surgery.

[44]  J. Cheetham,et al.  Efficacy and safety profile of ketorolac 0.5% ophthalmic solution in the prevention of surgically induced miosis during cataract surgery. , 1999, Clinical therapeutics.

[45]  J. Heier,et al.  Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial. , 1999, American journal of ophthalmology.

[46]  C. Siganos,et al.  Topical indomethacin solution versus dexamethasone solution for treatment of inflamed pterygium and pinguecula: a prospective randomized clinical study. , 1999, American journal of ophthalmology.

[47]  A. Flach,et al.  Comparative effects of ketorolac 0.5% or diclofenac 0.1% ophthalmic solutions on inflammation after cataract surgery. , 1998, Ophthalmology.

[48]  S. Isenberg,et al.  A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. , 1998, Ophthalmology.

[49]  J. A. Stewart,et al.  The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. , 1998, Ophthalmic surgery and lasers.

[50]  A. Chuang,et al.  A randomized double-masked trial comparing ketorolac tromethamine 0.5%, diclofenac sodium 0.1%, and prednisolone acetate 1% in reducing post-phacoemulsification flare and cells. , 1998, Ophthalmic surgery and lasers.

[51]  M. Raizman,et al.  A multicenter comparison of the ocular efficacy and safety of diclofenac 0.1% solution with that of ketorolac 0.5% solution in patients with acute seasonal allergic conjunctivitis. , 1998, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[52]  R. Yee,et al.  Analgesic efficacy and safety of nonpreserved ketorolac tromethamine ophthalmic solution following radial keratotomy. Ketorolac Radial Keratotomy Study Group. , 1998, American journal of ophthalmology.

[53]  K. Dickersin,et al.  Medical prophylaxis and treatment of cystoid macular edema after cataract surgery. The results of a meta-analysis. , 1998, Ophthalmology.

[54]  D. Apple,et al.  Topical 0.5% ketorolac vs 0.03% flurbiprofen for inhibition of miosis during cataract surgery. , 1997, Archives of ophthalmology.

[55]  P. Kaiser,et al.  A study of topical nonsteroidal anti-inflammatory drops and no pressure patching in the treatment of corneal abrasions. Corneal Abrasion Patching Study Group. , 1997, Ophthalmology.

[56]  R. Masi,et al.  Ketorolac, prednisolone, and dexamethasone for postoperative inflammation. , 1997, Clinical therapeutics.

[57]  M. Sharir Exacerbation of asthma by topical diclofenac. , 1997, Archives of ophthalmology.

[58]  P. Koay,et al.  Emerging roles of topical non-steroidal anti-inflammatory agents in ophthalmology , 1996, The British journal of ophthalmology.

[59]  P. Shvartzman,et al.  Acute bronchial asthma associated with the administration of ophthalmic indomethacin. , 1996, Israel journal of medical sciences.

[60]  C. Roberts,et al.  Pretreatment with topical diclofenac sodium to decrease postoperative inflammation. , 1996, Ophthalmology.

[61]  P. McDonnell,et al.  Comparison of In Vitro Antiproliferative Effects of Steroids and Nonsteroidal Antiinflammatory Drugs on Human Keratocytes , 1996, Cornea.

[62]  K. Tsubota,et al.  Persistent epithelial defect following penetrating keratoplasty: an adverse effect of diclofenac eyedrops. , 1995, Cornea.

[63]  C. Roberts,et al.  A comparison of topical diclofenac with prednisolone for postcataract inflammation. , 1995, Archives of ophthalmology.

[64]  P. McDonnell,et al.  Effect of diclofenac on corneal haze after photorefractive keratectomy in rabbits. , 1995, Ophthalmology.

[65]  A. Ginsburg,et al.  Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: Functional vision and contrast sensitivity , 1995, Journal of cataract and refractive surgery.

[66]  L. Solomon Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema , 1995, Journal of cataract and refractive surgery.

[67]  J. Garbus,et al.  Decrease in normal human corneal sensitivity with topical diclofenac sodium. , 1994, American journal of ophthalmology.

[68]  R. Krueger,et al.  Role of topical corticosteroids and nonsteroidal antiinflammatory drugs in the etiology of stromal infiltrates after excimer photorefractive keratectomy. , 1994, Journal of refractive and corneal surgery.

[69]  A. Gwon,et al.  Ocufen (flurbiprofen) in the treatment of ocular pain after radial keratotomy. , 1994, The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc.

[70]  Mark T. Johnson,et al.  Use of topical nonsteroidal anti‐inflammatory drugs in excimer laser photorefractive keratectomy , 1994, Journal of cataract and refractive surgery.

[71]  J. Gills Voltaren Associated with Medication Keratitis , 1994, Journal of cataract and refractive surgery.

[72]  S. Lane,et al.  Topical diclofenac in the treatment of ocular pain after excimer photorefractive keratectomy. , 1993, Refractive & corneal surgery.

[73]  S. Cillino,et al.  Topical flurbiprofen in extracapsular cataract surgery: Effect on pupillary diameter and iris fluorescein leakage , 1993, Journal of cataract and refractive surgery.

[74]  R. Hoffman,et al.  Topical diclofenac reduces pain following photorefractive keratectomy. , 1993, Archives of ophthalmology.

[75]  Khoa D. Nguyen,et al.  In vitro evaluation of antiproliferative potential of topical cyclooxygenase inhibitors in human Tenon's fibroblasts. , 1993, Experimental eye research.

[76]  G. Canonica,et al.  Topical anti-inflammatory drugs in the treatment of allergic pollinosic conjunctivitis: a comparative double-blind study. , 1992, Journal of investigational allergology & clinical immunology.

[77]  D. Lee,et al.  Effect of steroids and nonsteroidal antiinflammatory agents on human ocular fibroblast. , 1992, Investigative ophthalmology & visual science.

[78]  E. Bovey,et al.  Association diclofenac-dexamethasone dans le traitement de l'inflammation postopératoire: étude prospective en double-insu , 1992 .

[79]  L. Yannuzzi,et al.  Improvement in visual acuity in chronic aphakic and pseudophakic cystoid macular edema after treatment with topical 0.5% ketorolac tromethamine. , 1991, American journal of ophthalmology.

[80]  A. Flach,et al.  Prophylaxis of aphakic cystoid macular edema without corticosteroids. A paired-comparison, placebo-controlled double-masked study. , 1990, Ophthalmology.

[81]  D. Sanders,et al.  Inhibition of blood-aqueous humor barrier breakdown with diclofenac. A fluorophotometric study. , 1990, Archives of ophthalmology.

[82]  W. Chin,et al.  Acute asthma attack due to ophthalmic indomethacin. , 1989, Annals of internal medicine.

[83]  A. Flach,et al.  The effect of ketorolac tromethamine solution 0.5% in reducing postoperative inflammation after cataract extraction and intraocular lens implantation. , 1988, Ophthalmology.

[84]  J. McCulley,et al.  Suprofen treatment of contact lens-associated giant papillary conjunctivitis. , 1988, Ophthalmology.

[85]  A. Flach,et al.  Quantitative assessment of postsurgical breakdown of the blood-aqueous barrier following administration of 0.5% ketorolac tromethamine solution. A double-masked, paired comparison with vehicle-placebo solution study. , 1988, Archives of ophthalmology.

[86]  S. L. Severin,et al.  Pseudophakic cystoid macular edema: a revised comparison of the incidence with intracapsular and extracapsular cataract extraction. , 1988, Ophthalmic surgery.

[87]  A. Crandall,et al.  Reduction of pupillary constriction during cataract surgery using suprofen. , 1986, Archives of ophthalmology.

[88]  Keates Rh,et al.  The effect of topical indomethacin ophthalmic solution in maintaining mydriasis during cataract surgery. , 1984 .

[89]  M. Roch-Arveiller,et al.  In vivo effects of indomethacin and flurbiprofen on the locomotion of neutrophils elicited by immune and non-immune inflammation in the rat. , 1984, European journal of pharmacology.

[90]  Keates Rh,et al.  Clinical trial of flurbiprofen to maintain pupillary dilation during cataract surgery. , 1984 .

[91]  K. Miyake,et al.  Long-term follow-up study on prevention of aphakic cystoid macular oedema by topical indomethacin. , 1980, The British journal of ophthalmology.

[92]  T. Ozawa,et al.  Prevention of cystoid macular edema after lens extraction by topical indomethacin (III) radioimmunoassay measurement of prostaglandins in the aqueous during and after lens extraction procedures , 1978, Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie.

[93]  K. Miyake Prevention of cystoid macular edema after lens extraction by topical indomethacin (I) , 1977, Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie.

[94]  John A. Mills Nonsteroidal Anti-Inflammatory Drugs , 1974 .

[95]  W. Unger,et al.  Prostaglandins as mediators for the responses of the eye to trauma. , 1973, Experimental eye research.

[96]  M. Waitzman,et al.  Prostaglandin influences on intraocular pressure and pupil size. , 1967, The American journal of physiology.

[97]  N. Ambache,et al.  Effect of mechanical stimulation on rabbits' eyes: release of active substance in anterior chamber perfusates , 1965, The Journal of physiology.

[98]  E. Anggard,et al.  SMOOTH MUSCLE STIMULATING LIPIDS IN SHEEP IRIS. THE IDENTIFICATION OF PROSTAGLANDIN F 2A. PROSTAGLANDINS AND RELATED FACTORS 21. , 1964, Biochemical pharmacology.

[99]  L. Missotten,et al.  Efficacy and safety of Indomethacin 0.1% versus Flurbiprofen 0.03% eyedrops in inflammation after argon laser trabeculoplasty , 2005, Documenta Ophthalmologica.

[100]  P. Campochiaro,et al.  Topical nepafenac inhibits ocular neovascularization. , 2003, Investigative ophthalmology & visual science.

[101]  A. Flach Topical Nonsteroidal Antiinflammatory Drugs in Ophthalmology , 2002, International ophthalmology clinics.

[102]  R. Fiscella,et al.  Topical Nonsteroidal Anti-Inflammatory Drugs for Ophthalmic Use , 2002, Drug safety.

[103]  T. Oshika,et al.  Comparison of diclofenac and fluorometholone in preventing cystoid macular edema after small incision cataract surgery: a multicentered prospective trial. , 2000, Japanese journal of ophthalmology.

[104]  A. Flach The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery. , 1998, Transactions of the American Ophthalmological Society.

[105]  C. Foster,et al.  The Role of Nonsteroidal Antiinflammatory Drugs in Ocular Inflammation , 1996, International ophthalmology clinics.

[106]  C. Roberts Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis , 1996, Journal of cataract and refractive surgery.

[107]  W. Konen,et al.  Efficacy and tolerance of diclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation , 1996, Journal of cataract and refractive surgery.

[108]  J. Koester,et al.  Safety and efficacy of diclofenac sodium 0.1% ophthalmic solution in acute seasonal allergic conjunctivitis. , 1995, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[109]  A. Flach Cyclo-oxygenase inhibitors in ophthalmology. , 1992, Survey of ophthalmology.

[110]  H. Mishima,et al.  The putative role of prostaglandins in cystoid macular edema. , 1989, Progress in clinical and biological research.

[111]  K. Miyake Prevention of cystoid macular edema after lens extraction by topical indomethacin-2-A control study in bilateral extractions , 1978 .

[112]  K. Masuda,et al.  Topical indomethacin in soft cataract aspiration , 1976 .