Cross-priming of long lived protective CD8+ T cells against Trypanosoma cruzi infection: importance of a TLR9 agonist and CD4+ T cells.

[1]  R. Koup,et al.  T cell responses in nonhuman primates + quality of Th 1 and CD 8 HIV Gag protein conjugated to a Toll-like receptor 7 / 8 agonist improves the magnitude and Mattapallil , 2007 .

[2]  R. Gazzinelli,et al.  Long-term protective immunity induced against Trypanosoma cruzi infection after vaccination with recombinant adenoviruses encoding amastigote surface protein-2 and trans-sialidase. , 2006, Human gene therapy.

[3]  Alessandro Sette,et al.  CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes , 2006, PLoS pathogens.

[4]  Mario Roederer,et al.  Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates , 2006, The Journal of experimental medicine.

[5]  F. Tzelepis,et al.  Distinct Kinetics of Effector CD8+ Cytotoxic T Cells after Infection with Trypanosoma cruzi in Naïve or Vaccinated Mice , 2006, Infection and Immunity.

[6]  F. Sugauchi,et al.  Vigorous hepatitis C virus-specific CD4+ and CD8+ T cell responses induced by protein immunization in the presence of Montanide ISA720 plus synthetic oligodeoxynucleotides containing immunostimulatory cytosine-guanine dinucleotide motifs. , 2006, The Journal of infectious diseases.

[7]  Y. Takashima,et al.  Immune Responses against a Single CD8+-T-Cell Epitope Induced by Virus Vector Vaccination Can Successfully Control Trypanosoma cruzi Infection , 2005, Infection and Immunity.

[8]  R. Gazzinelli,et al.  CD8+-T-Cell-Dependent Control of Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain after Immunization with Recombinant Proteins Based on Amastigote Surface Protein 2 , 2005, Infection and Immunity.

[9]  C. Harding,et al.  Enhancement of Dendritic Cell Antigen Cross-Presentation by CpG DNA Involves Type I IFN and Stabilization of Class I MHC mRNA1 , 2005, The Journal of Immunology.

[10]  A. Hill,et al.  Novel Protein and Poxvirus-Based Vaccine Combinations for Simultaneous Induction of Humoral and Cell-Mediated Immunity1 , 2005, The Journal of Immunology.

[11]  D. Busch,et al.  Protective CD8 T Cell Immunity Triggered by CpG-Protein Conjugates Competes with the Efficacy of Live Vaccines1 , 2005, The Journal of Immunology.

[12]  H. Robinson,et al.  T cell vaccines for microbial infections , 2005, Nature Medicine.

[13]  R. Seder,et al.  CD 8 the Generation of HIV-1 Gag-Specific Th 1 Conjugated to a TLR 7 / 8 Agonist Results in Immunization with HIV-1 Gag Protein , 2005 .

[14]  Gabrielle T Belz,et al.  Cognate CD4+ T cell licensing of dendritic cells in CD8+ T cell immunity , 2004, Nature Immunology.

[15]  R. Tarleton,et al.  Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection , 2004, Immunological reviews.

[16]  R. Gazzinelli,et al.  Protective immunity against trypanosoma cruzi infection in a highly susceptible mouse strain after vaccination with genes encoding the amastigote surface protein-2 and trans-sialidase. , 2004, Human gene therapy.

[17]  M. Bevan,et al.  CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection , 2004, Nature Immunology.

[18]  B. Rouse,et al.  Concomitant Helper Response Rescues Otherwise Low Avidity CD8+ Memory CTLs to Become Efficient Effectors In Vivo1 , 2004, The Journal of Immunology.

[19]  D. Busch,et al.  CpG-DNA Aided Cross-Priming by Cross-Presenting B Cells1 , 2004, The Journal of Immunology.

[20]  E. Pamer,et al.  CD8 T cell responses to infectious pathogens. , 2003, Annual review of immunology.

[21]  S. Boscardin,et al.  Importance of CD8 T cell-mediated immune response during intracellular parasitic infections and its implications for the development of effective vaccines. , 2003, Anais da Academia Brasileira de Ciencias.

[22]  M. Betts,et al.  Prime-Boost Vaccination with HIV-1 Gag Protein and Cytosine Phosphate Guanosine Oligodeoxynucleotide, Followed by Adenovirus, Induces Sustained and Robust Humoral and Cellular Immune Responses 1 , 2003, The Journal of Immunology.

[23]  S. Boscardin,et al.  Immunization with cDNA Expressed by Amastigotes of Trypanosoma cruzi Elicits Protective Immune Response against Experimental Infection , 2003, Infection and Immunity.

[24]  M. Bevan,et al.  Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help , 2003, Science.

[25]  Hao Shen,et al.  Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory , 2003, Science.

[26]  M. Simon,et al.  Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent onthe FasL/Fas pathway , 2003, European journal of immunology.

[27]  Martin A. Nowak,et al.  Compromised Influenza Virus-Specific CD8+-T-Cell Memory in CD4+-T-Cell-Deficient Mice , 2002, Journal of Virology.

[28]  R. Tarleton,et al.  Genetic Immunization Elicits Antigen-Specific Protective Immune Responses and Decreases Disease Severity in Trypanosoma cruzi Infection , 2002, Infection and Immunity.

[29]  T. Aoki,et al.  Coadministration of an Interleukin-12 Gene and a Trypanosoma cruzi Gene Improves Vaccine Efficacy , 2002, Infection and Immunity.

[30]  E. Raz,et al.  IFN-αβ Promote Priming of Antigen-Specific CD8+ and CD4+ T Lymphocytes by Immunostimulatory DNA-Based Vaccines1 , 2002, The Journal of Immunology.

[31]  Chau‐Ching Liu,et al.  Evidence for a perforin‐mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection , 2002, International journal of experimental pathology.

[32]  L. Glimcher,et al.  Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease. , 1996, International immunology.

[33]  K. Kristensson,et al.  Differential susceptibilities of mice genomically deleted of CD4 and CD8 to infections with Trypanosoma cruzi or Trypanosoma brucei , 1993, Infection and immunity.

[34]  P. Palese,et al.  Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[35]  B. Koller,et al.  Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection , 1992, Nature.

[36]  Z. Brener,et al.  Protective effects of specific antibodies in Trypanosoma cruzi infections. , 1976, Journal of immunology.