Closed-Loop Control of Anaesthesia Using Fuzzy Logic

A multi-sensor fusion system for monitoring and control depth of anaesthesia in the operating theatre, is described. Two types of anaesthesia measures were considered, the first is based on auditory evoked brain potentials, while the second measure is based on cardiovascular system signals. The first measure is based on analyses of the signal using wavelets and neuro-fuzzy inference, while the second measure is based on analysis of the measurements using rule-based fuzzy logic. The two measures are combined via fuzzy logic to give a final level of depth of anaesthesia. The depth of anaesthesia level is fed back to a Target Controlled Infusion System (TCI) for controlling the infusion of the drug propofol for maintaining a constant level of depth of anaesthesia.

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