Hemicraniectomy in elderly patients with space occupying media infarction: improved survival but poor functional outcome

OBJECTIVE To assess the survival rate and functional outcome in elderly patients with space occupying supratentorial infarction who underwent hemicraniectomy compared with those who received medical treatment alone. METHODS All patients older than 55 years with space occupying middle cerebral artery (MCA) infarction treated in our clinic between January 1998 and July 1999 were included in this retrospective analysis. Patients were eligible for decompressive surgery if they were younger than 75 and had no severe comorbidity. Hemicraniectomy was performed regardless of the affected hemisphere. All patients were followed up for assessment of functional outcome; data were assessed according to the Barthel index and modified Rankin scale and cover a period of 3 to 9 months after infarction. RESULTS Twelve out of 24 patients underwent hemicraniectomy. Eight patients who were operated on survived; only one patient died of transtentorial herniation, three other deaths were due to medical complications. None of the survivors had a Barthel score above 60 or a Rankin score below 4. Nine out of 12 medically treated patients died of transtentorial herniation, one patient died of medical complications. The two surviving patients had a Barthel score below 60 and a Rankin score of 4. CONCLUSIONS Craniectomy in elderly patients with space occupying MCA infarction improves survival rates compared with medical treatment alone. However, functional outcome and level of independence are poor. Craniectomy in elderly patients should not be performed unless a prospective randomised trial proves beneficial.

[1]  D B Matchar,et al.  Incidence and occurrence of total (first-ever and recurrent) stroke. , 1999, Stroke.

[2]  C. Beaulieu,et al.  Decompressive craniectomy, reperfusion, or a combination for early treatment of acute "malignant" cerebral hemispheric stroke in rats? Potential mechanisms studied by MRI. , 1999, Stroke.

[3]  E. Wijdicks,et al.  Middle cerebral artery territory infarction and early brain swelling: progression and effect of age on outcome. , 1998, Mayo Clinic proceedings.

[4]  W Hacke,et al.  Early hemicraniectomy in patients with complete middle cerebral artery infarction. , 1998, Stroke.

[5]  F. Buonanno,et al.  One-year Outcome after Decompressive Surgery for Massive Nondominant Hemispheric Infarction , 1997 .

[6]  G. Nesbit,et al.  Direct carotid cavernous fistula after trigeminal balloon microcompression gangliolysis: case report. , 1996, Neurosurgery.

[7]  Decompressive craniectomy in a rat model of "malignant" cerebral hemispheric stroke: experimental support for an aggressive therapeutic approach. , 1996, Journal of neurosurgery.

[8]  W. Hacke,et al.  'Malignant' middle cerebral artery territory infarction : Clinical course and prognostic signs , 1996 .

[9]  H. Yonas,et al.  An aggressive approach to massive middle cerebral artery infarction. , 1993, Archives of neurology.

[10]  C. Mottolese,et al.  [Evaluation of the clinical benefit of decompression hemicraniectomy in intracranial hypertension not controlled by medical treatment]. , 1993, Neuro-Chirurgie.

[11]  W C Broaddus,et al.  Treatment of right hemispheric cerebral infarction by hemicraniectomy. , 1990, Stroke.

[12]  D. Kondziolka,et al.  Functional recovery after decompressive craniectomy for cerebral infarction. , 1988, Neurosurgery.

[13]  A. Ropper,et al.  Brain edema after stroke. Clinical syndrome and intracranial pressure. , 1984, Archives of neurology.

[14]  S. Batnitzky,et al.  Hemicraniectomy for acute massive cerebral infarction. , 1981, Neurosurgery.