Effects of brain-lesion size and location on temporal-order judgment

We assessed the effect of size and localization of a brain lesion on patients' abilities to perceive the temporal order of two acoustic stimuli. In those patients who had performed with impaired order thresholds, local overlaps of lesions as analyzed with CT were found in specific left-hemispheric regions of the temporal and parietal lobe. However, a moderate association of lesion size and temporal-order threshold was found among all brain-injured patients (n=30), a correlation that was most pronounced in patients with right-hemispheric lesions. This non-specific effect of lesion size has to be discussed critically with respect to behavioral findings of an association between temporal-processing abilities and language competence.

[1]  Manzar Ashtari,et al.  Left middle temporal gyrus activation during a phonemic discrimination task , 2004, Neuroreport.

[2]  P Tallal,et al.  Language learning impairment: integrating research and remediation. , 1998, Scandinavian journal of psychology.

[3]  M. Corbetta,et al.  A PET study of visuospatial attention , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[4]  Jirí Mates,et al.  A system for the assessment and training of temporal-order discrimination , 2001, Comput. Methods Programs Biomed..

[5]  J. Wearden,et al.  “Beyond the fields we know...”: exploring and developing scalar timing theory , 1999, Behavioural Processes.

[6]  G. Fesl,et al.  Auditory perception of temporal-spatial order —a fMRI-study , 2001, NeuroImage.

[7]  M. Wittmann,et al.  Time perception and temporal processing levels of the brain. , 1999, Chronobiology international.

[8]  A. Friederici,et al.  Phonological processing in language production: time course of brain activity , 2003, Neuroreport.

[9]  I J Hirsh,et al.  Brain damage and the ordering of two temporally successive stimuli. , 1972, Neuropsychologia.

[10]  M. Petrides.  The role of the mid-dorsolateral prefrontal cortex in working memory , 2000, Experimental Brain Research.

[11]  R. Efron.  TEMPORAL PERCEPTION, APHASIA AND D'EJ'A VU. , 1963, Brain : a journal of neurology.

[12]  A. Friederici.  Towards a neural basis of auditory sentence processing , 2002, Trends in Cognitive Sciences.

[13]  G. Rollman,et al.  Hemispheric asymmetry for auditory perception of temporal order , 1980, Neuropsychologia.

[14]  T Wüstenberg,et al.  Asymmetric hemodynamic responses of the human auditory cortex to monaural and binaural stimulation , 2002, Hearing Research.

[15]  Hans Strasburger,et al.  Auditory temporal-order judgement is impaired in patients with cortical lesions in posterior regions of the left hemisphere , 1999, Neuroscience Letters.

[16]  Stephen M. Rao,et al.  Human Brain Language Areas Identified by Functional Magnetic Resonance Imaging , 1997, The Journal of Neuroscience.

[17]  Steven L. Miller,et al.  Temporal Processing Deficits of Language-Learning Impaired Children Ameliorated by Training , 1996, Science.

[18]  R. Klein,et al.  The evidence for a temporal processing deficit linked to dyslexia: A review , 1995, Psychonomic bulletin & review.

[19]  M. Torrens.  Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268 , 1990 .

[20]  Ernst Pöppel,et al.  Daily Rhythm of Temporal Resolution in the Auditory System , 1999, Cortex.

[21]  Ernst Pöppel,et al.  Domains of rehabilitation: a theoretical perspective , 1993, Behavioural Brain Research.

[22]  R. Zatorre,et al.  Structure and function of auditory cortex: music and speech , 2002, Trends in Cognitive Sciences.

[23]  David Poeppel,et al.  The analysis of speech in different temporal integration windows: cerebral lateralization as 'asymmetric sampling in time' , 2003, Speech Commun..

[24]  E. Pöppel,et al.  Temporal order judgement for auditory and visual stimuli. , 2002, Acta neurobiologiae experimentalis.

[25]  H. Scheich,et al.  Phonetic Perception and the Temporal Cortex , 2002, NeuroImage.