Bmc Structural Biology Crystal Structure of the Yffb Protein from Pseudomonas Aeruginosa Suggests a Glutathione-dependent Thiol Reductase Function

Background: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein.

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