Optical propagation of blue LED light in brain tissue and Parylene-C

Understanding the propagation of LED light in the brain tissue can facilitate the advanced development of LED-based neuroprosthetic devices for optogenetic applications. In this work, the attenuation coefficient of blue LED light in thin tissue slices and Parylene-C films were quantified, which is 19.9 cm−1 and 1.70 cm−1, respectively. Optical simulations in TracePro show good agreement with the experiments.

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