Matrix metalloproteases and lung disease.

Development, tissue remodelling, cell migration, inflammation, angiogenesis, and wound healing are just some of the physiological processes in which the matrix metalloproteases (MMPs), a family of highly homologous endopeptidases, play a crucial part.'" Collectively the MMPs can cleave most, if not all, the protein constituents of the extracellular matrix including collagen, proteoglycan, laminin, fibronectin, and elastin. In so doing they facilitate cell movement, reorientation, and dispersal. The production and action of the MMPs

[1]  D. Demello,et al.  Hyperoxia induces interstitial (type I) and increases type IV collagenase mRNA expression and increases type I and IV collagenolytic activity in newborn rat lung. , 1994, Biology of the neonate.

[2]  T. Tetley.  New perspectives on basic mechanisms in lung disease. 6. Proteinase imbalance: its role in lung disease. , 1993, Thorax.

[3]  H. Birkedal‐Hansen,et al.  Role of Matrix Metalloproteinases in Human Periodontal Diseases. , 1993, Journal of periodontology.

[4]  Y. Soini,et al.  Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas. , 1993, The American journal of pathology.

[5]  D. Miles,et al.  Activity of type IV collagenases in benign and malignant breast disease. , 1993, British Journal of Cancer.

[6]  S. Zucker,et al.  Tetracycline and doxycycline inhibit pleural fluid metalloproteinases. A possible mechanism for chemical pleurodesis. , 1993, Chest.

[7]  R. Strieter,et al.  Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups , 1993, The Lancet.

[8]  H. Birkedal‐Hansen,et al.  Matrix metalloproteinases: a review. , 1993, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[9]  Y. Okada,et al.  Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema , 1992, Cell.

[10]  S. Zucker,et al.  Human pleural effusions are rich in matrix metalloproteinases. , 1992, Chest.

[11]  A. Kossakowska,et al.  Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas. , 1992, British Journal of Cancer.

[12]  J. Foidart,et al.  Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase. , 1992, Cancer research.

[13]  G. Raghu,et al.  Production of collagenase and tissue inhibitor of metalloproteinases by fibroblasts derived from normal and fibrotic human lungs. , 1992, Chest.

[14]  P. Bitterman.  Pathogenesis of fibrosis in acute lung injury. , 1992, The American journal of medicine.

[15]  L. Matrisian,et al.  Negative regulation of gene expression by TGF‐β , 1992 .

[16]  J. O'Connell,et al.  The role of the C-terminal domain in collagenase and stromelysin specificity. , 1992, The Journal of biological chemistry.

[17]  L. Matrisian,et al.  The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes. , 1992, The Journal of biological chemistry.

[18]  M. Cockett,et al.  The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases. , 1992, The Biochemical journal.

[19]  W. Stetler-Stevenson,et al.  Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. , 1992, Cancer research.

[20]  A. Strongin,et al.  Alanine scanning mutagenesis and functional analysis of the fibronectin-like collagen-binding domain from human 92-kDa type IV collagenase. , 1992, The Journal of biological chemistry.

[21]  D. Lovett,et al.  Proteinases and glomerular matrix turnover. , 1992, Kidney international.

[22]  M. Fini,et al.  COLLAGENOLYTIC/GELATINOLYTIC ENZYMES IN CORNEAL WOUND HEALING , 1992, Acta ophthalmologica. Supplement.

[23]  T. Hurskainen,et al.  Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization. , 1992, Cancer research.

[24]  H. Shimada,et al.  Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. , 1992, Cancer research.

[25]  E. Webb.  Enzyme nomenclature 1992. Recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology on the Nomenclature and Classification of Enzymes. , 1992 .

[26]  C. Brinckerhoff,et al.  Regulation of metalloproteinase gene expression: implications for osteoarthritis. , 1992, Critical reviews in eukaryotic gene expression.

[27]  P. Herrlich,et al.  Positive and negative regulation of collagenase gene expression. , 1992, Matrix (Stuttgart, Germany). Supplement.

[28]  P. Slocombe,et al.  Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes. , 1991, Biochimica et biophysica acta.

[29]  K. Suzuki,et al.  Substrate specificities and activation mechanisms of matrix metalloproteinases. , 1991, Biochemical Society transactions.

[30]  E. Howard,et al.  Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2. , 1991, The Journal of biological chemistry.

[31]  F. Sánchez‐Madrid,et al.  Mobilization of Gelatinase‐Rich Granules as a Regulatory Mechanism of Early Functional Responses in Human Neutrophils , 1991, Scandinavian journal of immunology.

[32]  J. McDonald,et al.  Cellular processes in lung repair. , 1991, Chest.

[33]  M. Selman,et al.  Collagenase and collagenase inhibitors in bronchoalveolar lavage fluids. , 1991, Chest.

[34]  W. Hanlon,et al.  rTNFa Facilitates Human Polymorphonuclear Leukocyte Adherence to Fibrinogen Matrices With Mobilization of Specific and Tertiary but Not Azurophilic Granule Markers , 2005 .

[35]  H. Birkedal‐Hansen,et al.  Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes. , 1991, The Journal of biological chemistry.

[36]  G. Opdenakker,et al.  Purification and identification of 91-kDa neutrophil gelatinase. Release by the activating peptide interleukin-8. , 1991, European journal of biochemistry.

[37]  J. Wrana,et al.  Induction of formative and resorptive cellular phenotypes in human gingival fibroblasts by TGF-beta 1 and concanavalin A: regulation of matrix metalloproteinases and TIMP. , 1991, Journal of periodontal research.

[38]  T. Petty.  Protease Mechanisms in the Pathogenesis of Acute Lung Injury , 1991, Annals of the New York Academy of Sciences.

[39]  B. Coulombe,et al.  Decreased expression of tissue inhibitor of metalloproteinases in metastatic tumor cells leading to increased levels of collagenase activity. , 1991, Cancer research.

[40]  E. Hay,et al.  Cell Biology of Extracellular Matrix , 1988, Springer US.

[41]  Z. Werb,et al.  Extracellular Matrix Degradation , 1991 .

[42]  G. Murphy.  The regulation of connective tissue metalloproteinases by natural inhibitors. , 1991, Agents and actions. Supplements.

[43]  U. Thorgeirsson,et al.  Studies on the ability of 65-kDa and 92-kDa tumor cell gelatinases to degrade type IV collagen. , 1990, The Journal of biological chemistry.

[44]  K. Brew,et al.  Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase. , 1990, Biochemistry.

[45]  J M Davidson,et al.  Biochemistry and turnover of lung interstitium. , 1990, The European respiratory journal.

[46]  K. Ward,et al.  Pulmonary disease progress in sarcoid patients with and without bronchoalveolar lavage collagenase. , 1990, The American review of respiratory disease.

[47]  L. Liotta,et al.  Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. , 1990, The Journal of biological chemistry.

[48]  B. Bresnihan,et al.  Bronchoalveolar lavage in patients with mild and severe rheumatoid lung disease. , 1990, Thorax.

[49]  J. P. Thompson,et al.  Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. , 1990, The Journal of biological chemistry.

[50]  H. Birkedal‐Hansen,et al.  The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[51]  M. Sporn,et al.  Transforming Growth Factor‐β in Rheumatoid Arthritis , 1990 .

[52]  G. Murphy,et al.  The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins. , 1990, Annals of the rheumatic diseases.

[53]  Z. Werb,et al.  Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells. , 1990, The Journal of biological chemistry.

[54]  L. Matrisian,et al.  Metalloproteinases and their inhibitors in matrix remodeling. , 1990, Trends in genetics : TIG.

[55]  B. Hogan,et al.  Growth factor-regulated proteases and extracellular matrix remodeling during mammalian development. , 1990, Current topics in developmental biology.

[56]  A. Eisen,et al.  SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. , 1989, The Journal of biological chemistry.

[57]  G. Murphy,et al.  The role of plasminogen in cell-mediated collagen degradation. , 1989, Cell biology international reports.

[58]  J. Wrana,et al.  Transforming growth factor-beta regulation of collagenase, 72 kDa-progelatinase, TIMP and PAI-1 expression in rat bone cell populations and human fibroblasts. , 1989, Connective tissue research.

[59]  J. Woessner,et al.  Purification and properties of a small latent matrix metalloproteinase of the rat uterus. , 1988, The Journal of biological chemistry.

[60]  L. Matrisian,et al.  Structure-function relationships in the collagenase family member transin. , 1988, The Journal of biological chemistry.

[61]  R. Chapela,et al.  Lung collagen metabolism and the clinical course of hypersensitivity pneumonitis. , 1988, Chest.

[62]  A. van Breda,et al.  Collagenase and fibronectin in bronchoalveolar lavage fluid in patients with sarcoidosis. , 1988, Thorax.

[63]  J. Travis,et al.  Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases , 1988, FEBS letters.

[64]  C. Odlum,et al.  Collagenase andfibronectin inbronchoalveolar lavage fluid inpatients withsarcoidosis , 1988 .

[65]  P. Stephens,et al.  Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes. , 1987, The Biochemical journal.

[66]  H. Welgus,et al.  Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts. , 1987, The Journal of clinical investigation.

[67]  H. Birkedal‐Hansen,et al.  Sequence specificity of human skin fibroblast collagenase. Evidence for the role of collagen structure in determining the collagenase cleavage site. , 1987, The Journal of biological chemistry.

[68]  J. Gadek,et al.  Neutrophil collagenase in rheumatoid interstitial lung disease. , 1987, Journal of applied physiology.

[69]  L. Boxer,et al.  Association between gelatinase release and increased plasma membrane expression of the Mo1 glycoprotein. , 1987, Blood.

[70]  T. Cawston,et al.  Preferential binding of collagenase to α2‐macroglobulin in the presence of the tissue inhibitor of metalloproteinases , 1986, FEBS letters.

[71]  S. Weiss,et al.  Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[72]  J. Falloon,et al.  Neutrophil granules in health and disease. , 1986, The Journal of allergy and clinical immunology.

[73]  R. Chapela,et al.  Concentration, biosynthesis and degradation of collagen in idiopathic pulmonary fibrosis. , 1986, Thorax.

[74]  L. Liotta,et al.  Transient expression of type IV collagenolytic metalloproteinase by human mononuclear phagocytes. , 1986, The Journal of biological chemistry.

[75]  P. Dorinsky,et al.  Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance. , 1986, The American review of respiratory disease.

[76]  A. Fein,et al.  Collagenase in the lower respiratory tract of patients with adult respiratory distress syndrome. , 2015, The American review of respiratory disease.

[77]  J. Reynolds,et al.  Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen. , 1985, Biochimica et biophysica acta.

[78]  J. Seyer,et al.  Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase. , 1985, The Journal of biological chemistry.

[79]  G. Raghu,et al.  Extracellular matrix in normal and fibrotic human lungs. , 1985, The American review of respiratory disease.

[80]  A. Kang,et al.  Secretion of collagenolytic enzymes by human polymorphonuclear leukocytes. , 1984, Collagen and related research.

[81]  J. Seyer,et al.  Purification of a type V collagen degrading metalloproteinase from rabbit alveolar macrophages. , 1984, Collagen and related research.

[82]  R. Crystal,et al.  Role of connective tissue proteases in the pathogenesis of chronic inflammatory lung disease. , 1984, Environmental health perspectives.

[83]  R. Crystal,et al.  Pulmonary asbestosis and idiopathic pulmonary fibrosis: pathogenetic parallels. , 1981, Chest.

[84]  L. Liotta,et al.  Metastatic potential correlates with enzymatic degradation of basement membrane collagen , 1980, Nature.

[85]  R. Crystal,et al.  Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis. , 1979, The New England journal of medicine.

[86]  J. Gallin,et al.  Secretory responses of human neutrophils: exocytosis of specific (secondary) granules by human neutrophils during adherence in vitro and during exudation in vivo. , 1979, Journal of immunology.

[87]  S. Krane,et al.  An endopeptidase from rheumatoid synovial tissue culture. , 1972, Biochimica et biophysica acta.

[88]  • Epidermis,et al.  WOUND healing. , 1959, The Medical journal of Australia.