Real-time Monitoring of the Interactions of Transforming Growth Factor-β (TGF-β) Isoforms with Latency-associated Protein and the Ectodomains of the TGF-β Type II and III Receptors Reveals Different Kinetic Models and Stoichiometries of Binding*
暂无分享,去创建一个
M. O’Connor-McCourt | M. Tsang | G. De Crescenzo | J. Zwaagstra | S. Grothé | M D O'Connor-McCourt | G De Crescenzo | S Grothe | J Zwaagstra | M Tsang
[1] M. Waterfield,et al. Epidermal growth factor binding induces a conformational change in the external domain of its receptor. , 1989, The EMBO journal.
[2] E. Chambaz,et al. Analysis of small latent transforming growth factor-beta complex formation and dissociation by surface plasmon resonance. Absence of direct interaction with thrombospondins. , 1997, The Journal of biological chemistry.
[3] A. Plückthun,et al. Model and simulation of multivalent binding to fixed ligands. , 1998, Analytical biochemistry.
[4] M. O’Connor-McCourt,et al. Down-regulation of transforming growth factor-beta receptors: cooperativity between the types I, II, and III receptors and modulation at the cell surface. , 1999, Experimental cell research.
[5] M. Grütter,et al. Ligand-induced dimerization of the extracellular domain of the TGF-beta receptor type II. , 1996, Biochemical and biophysical research communications.
[6] M. O’Connor-McCourt,et al. Analysis of the Interaction between Two TGF‐β‐binding Proteins and Three TGF‐β Isoforms Using Surface Plasmon Resonance , 1995 .
[7] M. O’Connor-McCourt,et al. Characterization of recombinant soluble human transforming growth factor-β receptor Type II (rhTGF-βsRII) , 1995 .
[8] R. W. Padgett,et al. TGF‐β signaling, Smads, and tumor suppressors , 1998 .
[9] D. Vivien,et al. Chimeric extracellular domain type II transforming growth factor (TGF)-beta receptor fused to the Fc region of human immunoglobulin as a TGF-beta antagonist. , 1998, European journal of biochemistry.
[10] M. Sporn,et al. Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. , 1996, Biochemistry.
[11] M. O’Connor-McCourt,et al. Ectodomain cleavage and shedding of the type III transforming growth factor‐β receptor in lung membranes , 1999 .
[12] Jeffrey L. Wrana,et al. TGFβ signals through a heteromeric protein kinase receptor complex , 1992, Cell.
[13] D. Davies,et al. Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily. , 1992, Science.
[14] Raymond B. Runyan,et al. Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart. , 1999, Science.
[15] E. Ruoslahti,et al. Betaglycan has multiple binding sites for transforming growth factor-beta 1. , 1996, The Biochemical journal.
[16] J. Massagué,et al. TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders , 2000, Cell.
[17] J. Massagué,et al. Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites , 1994, The Journal of cell biology.
[18] I. Chaiken,et al. Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration. , 1995, Analytical biochemistry.
[19] J. Dignam,et al. Structural characterization of the latent complex between transforming growth factor beta 1 and beta 1-latency-associated peptide. , 1996, Biochemical Journal.
[20] D. Rifkin,et al. An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. , 1994, Analytical biochemistry.
[21] T. Kirsch,et al. Crystal structure of the BMP-2–BRIA ectodomain complex , 2000, Nature Structural Biology.
[22] M. O’Connor-McCourt,et al. Real-time kinetic studies on the interaction of transforming growth factor alpha with the epidermal growth factor receptor extracellular domain reveal a conformational change model. , 2000, Biochemistry.
[23] A. Taniguchi,et al. Ligand-dependent and -independent interactions with the transforming growth factor type II and I receptor subunits reside in the aminoterminal portion of the ectodomain of the type III subunit , 1998, In Vitro Cellular & Developmental Biology - Animal.
[24] M. Sporn,et al. Transforming growth factor-beta: recent progress and new challenges , 1992, The Journal of cell biology.
[25] Harvey F. Lodish,et al. Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling* , 2001, The Journal of Biological Chemistry.
[26] M. O’Connor-McCourt,et al. Mutagenesis analysis of the membrane‐proximal ligand binding site of the TGF‐β receptor type III extracellular domain , 1995, FEBS letters.
[27] M. O’Connor-McCourt,et al. Mapping of the ligand binding domain of the transforming growth factor beta receptor type III by deletion mutagenesis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[28] E. Friedman,et al. Differential responsiveness to autocrine and exogenous transforming growth factor (TGF) beta1 in cells with nonfunctional TGF-beta receptor type III. , 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[29] R. Fisher,et al. BIAcore for macromolecular interaction. , 1998, Current opinion in biotechnology.
[30] H. Lodish,et al. The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand. , 1993, The Journal of biological chemistry.
[31] D. Winzor,et al. Interpretation of deviations from pseudo-first-order kinetic behavior in the characterization of ligand binding by biosensor technology. , 1996, Analytical biochemistry.
[32] H. Lodish,et al. Oligomeric Structure of Type I and Type II Transforming Growth Factor β Receptors: Homodimers Form in the ER and Persist at the Plasma Membrane , 1998, The Journal of cell biology.
[33] W. Press,et al. Numerical Recipes: The Art of Scientific Computing , 1987 .
[34] S. Wahl,et al. Inflammatory and immunomodulatory roles of TGF-β , 1989 .
[35] J. Massagué. TGF-beta signal transduction. , 1998, Annual review of biochemistry.
[36] D. Marquardt. An Algorithm for Least-Squares Estimation of Nonlinear Parameters , 1963 .
[37] M. Grütter,et al. The crystal structure of TGF‐β3 and comparison to TGF‐β2: Implications for receptor binding , 1996, Protein science : a publication of the Protein Society.
[38] L. Gentry,et al. The pro domain of pre-pro-transforming growth factor beta 1 when independently expressed is a functional binding protein for the mature growth factor. , 1990, Biochemistry.
[39] H. Lodish,et al. The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands. , 1995, The Journal of biological chemistry.
[40] R. Fisher,et al. Surface plasmon resonance based methods for measuring the kinetics and binding affinities of biomolecular interactions. , 1994, Current opinion in biotechnology.
[41] J. Massagué,et al. Betaglycan presents ligand to the TGFβ signaling receptor , 1993, Cell.