Design considerations in the development of a core outcome set
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No gold standard method currently exists for the development of a core outcome set (COS) although key issues to consider have been identified [1]. Methodological decisions in the design of a project to develop a COS for otitis media with effusion (OME) in children with cleft palate (CP) will be explained.
[1] Jane M Blazeby,et al. Developing core outcome sets for clinical trials: issues to consider , 2012, Trials.