Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

[1]  Jia Liu,et al.  Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma , 2013, BMC Cancer.

[2]  Xiaowei Xu,et al.  Snail1 mediates hypoxia-induced melanoma progression. , 2011, The American journal of pathology.

[3]  W. Ding,et al.  Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics , 2011, BMC Cancer.

[4]  M. Post,et al.  Mouse Snail Is a Target Gene for HIF , 2011, Molecular Cancer Research.

[5]  Jia Liu,et al.  5/35 fiber-modified conditionally replicative adenovirus armed with p53 shows increased tumor-suppressing capacity to breast cancer cells. , 2011, Human gene therapy.

[6]  B. Copple.  Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia‐inducible factor and transforming growth factor‐β‐dependent mechanisms , 2010, Liver international : official journal of the International Association for the Study of the Liver.

[7]  B. Zhou,et al.  Inflammation: a driving force speeds cancer metastasis. , 2009, Cell cycle.

[8]  S. Chiou,et al.  Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma , 2009, Hepatology.

[9]  V. Haase.  Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease. , 2009, Kidney international.

[10]  C. Khanna,et al.  Revisiting the seed and soil in cancer metastasis. , 2009, The international journal of biochemistry & cell biology.

[11]  M. Bar‐eli,et al.  Inflammation and melanoma metastasis , 2009, Pigment cell & melanoma research.

[12]  D. Hedley,et al.  Cancer stem cells, hypoxia and metastasis. , 2009, Seminars in radiation oncology.

[13]  E. Rakovitch,et al.  Tolerance and acceptance results of a palladium-103 permanent breast seed implant Phase I/II study. , 2009, International journal of radiation oncology, biology, physics.

[14]  R. Hill,et al.  Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors , 2009, Laboratory Investigation.

[15]  Yutaka Kawakami,et al.  Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells. , 2009, Cancer cell.

[16]  John S. Condeelis,et al.  Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination , 2009, Clinical Cancer Research.

[17]  G. Lorusso,et al.  The tumor microenvironment and its contribution to tumor evolution toward metastasis , 2008, Histochemistry and Cell Biology.

[18]  S. Ye,et al.  [Relationship between epithelial-mesenchymal transition and lung metastasis in hepatocellular carcinoma]. , 2008, Zhonghua wai ke za zhi [Chinese journal of surgery].

[19]  Yuanxing Zhang,et al.  Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1 alpha expression in colon carcinoma cells. , 2008, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[20]  Kou-Juey Wu,et al.  TWIST activation by hypoxia inducible factor-1 (HIF-1): Implications in metastasis and development , 2008, Cell cycle.

[21]  R. Vessella,et al.  Cancer micrometastasis and tumour dormancy   , 2008, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[22]  E. Thompson,et al.  EMT and MET in carcinoma—clinical observations, regulatory pathways and new models , 2008, Clinical & Experimental Metastasis.

[23]  M. Hendrix,et al.  Hypoxia/reoxygenation: A dynamic regulator of lysyl oxidase‐facilitated breast cancer migration , 2008, Journal of cellular biochemistry.

[24]  T. Yoshizumi,et al.  Expression of Hypoxia-Inducible Factor-1&agr;, Histone Deacetylase 1, and Metastasis-Associated Protein 1 in Pancreatic Carcinoma: Correlation With Poor Prognosis With Possible Regulation , 2008, Pancreas.

[25]  J. Huot,et al.  Role of Cancer Microenvironment in Metastasis: Focus on Colon Cancer , 2008, Cancer Microenvironment.

[26]  C. Rinker-Schaeffer,et al.  Using metastasis suppressor proteins to dissect interactions among cancer cells and their microenvironment , 2008, Cancer and Metastasis Reviews.

[27]  A. Vincent-Salomon,et al.  A “class action” against the microenvironment: do cancer cells cooperate in metastasis? , 2008, Cancer and Metastasis Reviews.

[28]  D. Chappard,et al.  Interactions between microenvironment and cancer cells in two animal models of bone metastasis , 2008, British Journal of Cancer.

[29]  T. Molloy,et al.  Recent advances in metastasis research. , 2008, Current opinion in genetics & development.

[30]  A. Albini,et al.  Metastasis signatures: genes regulating tumor–microenvironment interactions predict metastatic behavior , 2007, Cancer and Metastasis Reviews.

[31]  R. Kalluri,et al.  Mechanisms of metastasis: Epithelial‐to‐mesenchymal transition and contribution of tumor microenvironment , 2007, Journal of cellular biochemistry.

[32]  Helen H. W. Chen,et al.  Hypoxia-inducible factor-1α correlates with MET and metastasis in node-negative breast cancer , 2007, Breast Cancer Research and Treatment.

[33]  M. Simon,et al.  Metastasis and stem cell pathways , 2007, Cancer and Metastasis Reviews.

[34]  R. Johnson,et al.  Hypoxia-Inducible Factor-1α Is a Key Regulator of Metastasis in a Transgenic Model of Cancer Initiation and Progression , 2007 .

[35]  J. A. van der Laak,et al.  Development of the tumor vascular bed in response to hypoxia‐induced VEGF‐A differs from that in tumors with constitutive VEGF‐A expression , 2006, International journal of cancer.

[36]  G. Berx,et al.  VHL Promotes E2 Box-Dependent E-Cadherin Transcription by HIF-Mediated Regulation of SIP1 and Snail , 2006, Molecular and Cellular Biology.

[37]  G. Christofori.  New signals from the invasive front , 2006, Nature.

[38]  Quynh-Thu Le,et al.  Lysyl oxidase is essential for hypoxia-induced metastasis , 2006, Nature.

[39]  Thomas Kirchner,et al.  Invasion and Metastasis in Colorectal Cancer: Epithelial-Mesenchymal Transition, Mesenchymal-Epithelial Transition, Stem Cells and β-Catenin , 2005, Cells Tissues Organs.

[40]  K. Blackwell,et al.  Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy? , 2004, The oncologist.

[41]  G. Semenza,et al.  Hydroxylation of HIF-1: oxygen sensing at the molecular level. , 2004, Physiology.

[42]  H. Moch,et al.  Chemokine receptor CXCR4 downregulated by von Hippel–Lindau tumour suppressor pVHL , 2003, Nature.

[43]  P. V. van Diest,et al.  Levels of hypoxia‐inducible factor‐1α independently predict prognosis in patients with lymph node negative breast carcinoma , 2003, Cancer.

[44]  M. Schindl,et al.  Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

[45]  J. Downward,et al.  Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis , 2002, The Journal of Cell Biology.

[46]  J. Zavadil,et al.  Genetic programs of epithelial cell plasticity directed by transforming growth factor-β , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[47]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[48]  J. Thiery,et al.  Epithelium‐mesenchyme interconversion as example of epithelial plasticity , 1993, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[49]  Xingbin Hu,et al.  Blockade of Notch signaling in tumor-bearing mice may lead to tumor regression, progression, or metastasis, depending on tumor cell types. , 2009, Neoplasia.

[50]  Valerie M. Weaver,et al.  Three-dimensional context regulation of metastasis , 2008, Clinical & Experimental Metastasis.

[51]  Jean Pouliot,et al.  Surgical resection and permanent iodine-125 brachytherapy for brain metastases , 2008, Journal of Neuro-Oncology.

[52]  A. Chambers.  Influence of diet on metastasis and tumor dormancy , 2008, Clinical & Experimental Metastasis.

[53]  Helen H. W. Chen,et al.  Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancer. , 2007, Breast cancer research and treatment.

[54]  J. Downward,et al.  Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. , 2002, The Journal of cell biology.

[55]  Leila Mohammadi,et al.  BMC Cancer , 2001 .

[56]  G. Semenza,et al.  Hypoxia, HIF-1, and the pathophysiology of common human diseases. , 2000, Advances in experimental medicine and biology.