Biodegradable Nanoparticles for Drug Delivery and Targeting

The application of nano-biotechnology in pharmacology is very interesting. The nano-biotechnology can be applied in many steps including drug delivery and targeting. Several new nanoparticles are developed to serve those purposes. In this specific chapter, the author will focus on the biodegradable nanoparticles which can be automatic degraded. The application of biodegradable nanoparticles for drug delivery and targeting will be summarized and presented in this article. Summary on important reports on this topic is also provided in this article.

[1]  Xinguo Jiang,et al.  Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: preparation, characterization and efficacy in Parkinson's disease. , 2011, International journal of pharmaceutics.

[2]  Yunfeng Lin,et al.  Toxicity of biodegradable nanoscale preparations. , 2012, Current drug metabolism.

[3]  Z. Qian,et al.  Preparation of core cross-linked PCL-PEG-PCL micelles for doxorubicin delivery in vitro. , 2011, Journal of nanoscience and nanotechnology.

[4]  Zhiwei Zhao,et al.  Design of PLGA-functionalized quercetin nanoparticles for potential use in Alzheimer's disease. , 2016, Colloids and surfaces. B, Biointerfaces.

[5]  Lijuan Chen,et al.  Poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) (PCL-PEG-PCL) nanoparticles for honokiol delivery in vitro. , 2009, International journal of pharmaceutics.

[6]  L. Paniwnyk,et al.  Overcoming T. gondii infection and intracellular protein nanocapsules as biomaterials for ultrasonically controlled drug release. , 2017, Biomaterials science.

[7]  M. Kumar,et al.  Intracellular delivery of peptide cargos using polyhydroxybutyrate based biodegradable nanoparticles: Studies on antitumor efficacy of BCL-2 converting peptide, NuBCP-9. , 2016, International journal of pharmaceutics.

[8]  Ravi Shankaran Dhesingh,et al.  Nanoparticle Modified Drug Loaded Biodegradable Polymeric Contact Lenses for Sustainable Ocular Drug Delivery. , 2017, Current drug delivery.

[9]  A. Camins,et al.  New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9. , 2017, Nanomedicine : nanotechnology, biology, and medicine.

[10]  Gilles Gnacadja,et al.  An Invitation to Pharmacostatics , 2019, Bulletin of mathematical biology.

[11]  Amareshwar T. K. Singh,et al.  Update on Nanotechnology-based Drug Delivery Systems in Cancer Treatment. , 2017, Anticancer research.

[12]  V. Wiwanitkit.  Interest in paromomycin for the treatment of visceral leishmaniasis (kala-azar) , 2012, Therapeutics and clinical risk management.

[13]  Yuquan Wei,et al.  Poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) nanoparticles: preparation, characterization, and application in doxorubicin delivery. , 2009, The journal of physical chemistry. B.

[14]  E. Carro,et al.  Enhanced Hippocampal Neurogenesis in APP/Ps1 Mouse Model of Alzheimer's Disease After Implantation of VEGF-loaded PLGA Nanospheres. , 2015, Current Alzheimer research.

[15]  G. Kwon,et al.  Thermosensitive poly-(d,l-lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly-(d,l-lactide-co-glycolide) hydrogels for multi-drug delivery , 2014, Journal of drug targeting.

[16]  B. Rolando,et al.  Liposomal nitrooxy-doxorubicin: one step over caelyx in drug-resistant human cancer cells. , 2014, Molecular pharmaceutics.

[17]  Lingxue Kong,et al.  Manufacturing Techniques and Surface Engineering of Polymer Based Nanoparticles for Targeted Drug Delivery to Cancer , 2016, Nanomaterials.

[18]  M. Gou,et al.  Efficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene , 2016, International journal of nanomedicine.

[19]  Jianping Qi,et al.  Absorption, disposition and pharmacokinetics of solid lipid nanoparticles. , 2012, Current drug metabolism.

[20]  J. S. Suk,et al.  Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors. , 2017, Journal of controlled release : official journal of the Controlled Release Society.

[21]  V. Wiwanitkit,et al.  Effect of gold nanoparticle on the microscopic morphology of white blood cell , 2009, Cytopathology : official journal of the British Society for Clinical Cytology.

[22]  M. Montazer,et al.  A Review on Applications of Liposomes in Textile Processing , 2008, Journal of liposome research.

[23]  Huile Gao,et al.  Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma. , 2015, Nanoscale.

[24]  J. Pemán,et al.  Comparative in vitro Antifungal Activity of Amphotericin B Lipid Complex, Amphotericin B and Fluconazole , 2000, Chemotherapy.

[25]  R. Jain,et al.  Potential Gene Therapy Towards Treating Neurodegenerative Disea ses Employing Polymeric Nanosystems. , 2017, Current gene therapy.

[26]  Chen Jiang,et al.  Angiopep-Conjugated Nanoparticles for Targeted Long-Term Gene Therapy of Parkinson’s Disease , 2013, Pharmaceutical Research.

[27]  J. Huwyler,et al.  PEG‐PCL‐based nanomedicines: A biodegradable drug delivery system and its application , 2017, Journal of controlled release : official journal of the Controlled Release Society.

[28]  W. Wan,et al.  Use of degradable and nondegradable nanomaterials for controlled release. , 2007, Nanomedicine.

[29]  Xiaohua Wang,et al.  Biodegradable Polymeric Nanoparticles as the Delivery Carrier for Drug. , 2016, Current drug delivery.

[30]  V. Wiwanitkit,et al.  Identification of gold nanoparticle in lymphocytes: a confirmation of direct intracellular penetration effect. , 2009, Turkish journal of haematology : official journal of Turkish Society of Haematology.

[31]  M. S. Muthu,et al.  Copolymers of poly(lactic acid) and d-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicines: versatile multifunctional platforms for cancer diagnosis and therapy , 2013, Expert opinion on drug delivery.

[32]  Wei Wu,et al.  Absorption, disposition and pharmacokinetics of nanoemulsions. , 2012, Current drug metabolism.

[33]  I. Rupenthal,et al.  Nanoparticle-loaded biodegradable light-responsive in situ forming injectable implants for effective peptide delivery to the posterior segment of the eye. , 2017, Medical hypotheses.

[34]  A. Elaissari,et al.  Nanoprecipitation process: From encapsulation to drug delivery. , 2017, International journal of pharmaceutics.

[35]  Li Qingshan,et al.  Zirconium phosphatidylcholine-based nanocapsules as an in vivo degradable drug delivery system of MAP30, a momordica anti-HIV protein. , 2015, International journal of pharmaceutics.

[36]  S. Salehi,et al.  Poly (glycerol sebacate)-poly (ε-caprolactone) blend nanofibrous scaffold as intrinsic bio- and immunocompatible system for corneal repair. , 2017, Acta biomaterialia.

[37]  M. Jayakannan,et al.  Development of l-Tyrosine-Based Enzyme-Responsive Amphiphilic Poly(ester-urethane) Nanocarriers for Multiple Drug Delivery to Cancer Cells. , 2017, Biomacromolecules.

[38]  V. Wiwanitkit,et al.  Effect of Gold Nanoparticle on Renal Cell: An Implication for Exposure Risk , 2008, Renal failure.

[39]  A. Mahmoud,et al.  PLGA Nanoparticles as Subconjunctival Injection for Management of Glaucoma , 2017, AAPS PharmSciTech.

[40]  Jia-You Fang,et al.  Lipid-Based Nanoparticles as a Potential Delivery Approach in the Treatment of Rheumatoid Arthritis , 2018, Nanomaterials.

[41]  R. Urman,et al.  Liposomal bupivacaine and clinical outcomes. , 2014, Best practice & research. Clinical anaesthesiology.

[42]  A. Schneeweiss,et al.  Efficacy and toxicity profile of pegylated liposomal doxorubicin (Caelyx) in patients with advanced breast cancer , 2014, Anti-cancer drugs.

[43]  A. Lasham,et al.  Development of biodegradable PLGA nanoparticles surface engineered with hyaluronic acid for targeted delivery of paclitaxel to triple negative breast cancer cells. , 2017, Materials science & engineering. C, Materials for biological applications.

[44]  Jeffery E. Raymond,et al.  Degradable polyphosphoester-based silver-loaded nanoparticles as therapeutics for bacterial lung infections. , 2015, Nanoscale.

[45]  Lin Mei,et al.  The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment. , 2014, Biomaterials.

[46]  K. Pathak,et al.  Lipid Nanoparticles: A Novel Approach for Brain Targeting. , 2018, Pharmaceutical nanotechnology.

[47]  Youxin Li,et al.  Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment , 2016, International journal of nanomedicine.

[48]  G. Kwon,et al.  PEG-b-PLA micelles and PLGA-b-PEG-b-PLGA sol-gels for drug delivery. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[49]  J. Suksiriworapong,et al.  Comparison of poly(ε-caprolactone) chain lengths of poly(ε-caprolactone)-co-d-α-tocopheryl-poly(ethylene glycol) 1000 succinate nanoparticles for enhancement of quercetin delivery to SKBR3 breast cancer cells. , 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[50]  W. Saltzman,et al.  Degradable bioadhesive nanoparticles for prolonged intravaginal delivery and retention of elvitegravir. , 2017, Biomaterials.

[51]  S. Ramamoorthy,et al.  The Safety of Liposome Bupivacaine, A Novel Local Analgesic Formulation , 2013, The Clinical journal of pain.