History, evolution, and trends in compound management for high throughput screening.

Growth in compound library size with increasing levels of high throughput screening has resulted in the complementary development of automated hardware and software systems for compound management. The history of this technology from its emergence in the early 1990s, its current status, and future trends are all described. The perspective is primarily a personal one, based on the author's involvement with compound management from its outset to the present day.

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