A Gating Mechanism of the Serotonin 5-HT3 Receptor.
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[1] R. Dutzler,et al. X-ray structure of a prokaryotic pentameric ligand-gated ion channel , 2008, Nature.
[2] M. Bansal,et al. HELANAL: A Program to Characterize Helix Geometry in Proteins , 2000, Journal of biomolecular structure & dynamics.
[3] Guido Scarabelli,et al. Kinesin-5 Allosteric Inhibitors Uncouple the Dynamics of Nucleotide, Microtubule, and Neck-Linker Binding Sites , 2014, Biophysical journal.
[4] H. Lester,et al. The structural basis of function in Cys-loop receptors , 2010, Quarterly Reviews of Biophysics.
[5] David R. Westhead,et al. Calculation of Helix Packing Angles in Protein Structures , 2003, Bioinform..
[6] Marc Baaden,et al. One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue , 2010, Proceedings of the National Academy of Sciences.
[7] S. Sine,et al. Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors , 2009, The Journal of Neuroscience.
[8] Thomas Wieland,et al. Alignment-Annotator web server: rendering and annotating sequence alignments , 2014, Nucleic Acids Res..
[9] B. Wallace,et al. HOLE: a program for the analysis of the pore dimensions of ion channel structural models. , 1996, Journal of molecular graphics.
[10] N. Unwin,et al. Structure and superorganization of acetylcholine receptor–rapsyn complexes , 2013, Proceedings of the National Academy of Sciences.
[11] Matthieu Chavent,et al. Bendix: intuitive helix geometry analysis and abstraction , 2012, Bioinform..
[12] P. Paoletti,et al. Synaptic neurotransmitter-gated receptors. , 2012, Cold Spring Harbor perspectives in biology.
[13] Andrei L. Lomize,et al. Anisotropic Solvent Model of the Lipid Bilayer. 2. Energetics of Insertion of Small Molecules, Peptides, and Proteins in Membranes , 2011, J. Chem. Inf. Model..
[14] J. Baenziger,et al. Gating of pentameric ligand-gated ion channels: structural insights and ambiguities. , 2013, Structure.
[15] T. Tomizaki,et al. X-ray structure of the mouse serotonin 5-HT3 receptor , 2014, Nature.
[16] John H. Morris,et al. structureViz: linking Cytoscape and UCSF Chimera , 2007, Bioinform..
[17] Surajit Banerjee,et al. X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors , 2014, Nature.
[18] Conrad C. Huang,et al. Visualizing density maps with UCSF Chimera. , 2007, Journal of structural biology.
[19] Sukjoon Yoon,et al. QHELIX: A Computational Tool for the Improved Measurement of Inter-Helical Angles in Proteins , 2007, The protein journal.
[20] Evan Bolton,et al. PubChem's BioAssay Database , 2011, Nucleic Acids Res..
[21] R. Doolittle,et al. A simple method for displaying the hydropathic character of a protein. , 1982, Journal of molecular biology.
[22] M. Delarue,et al. Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels. , 2015, Biochimica et biophysica acta.
[23] Antoine Taly,et al. Ligand-gated ion channels: new insights into neurological disorders and ligand recognition. , 2012, Chemical reviews.
[24] J. A. Peters,et al. Novel structural determinants of single channel conductance and ion selectivity in 5‐hydroxytryptamine type 3 and nicotinic acetylcholine receptors , 2010, The Journal of physiology.
[25] Jan H. Jensen,et al. Improved Treatment of Ligands and Coupling Effects in Empirical Calculation and Rationalization of pKa Values. , 2011, Journal of chemical theory and computation.
[26] Oliver Beckstein,et al. A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor , 2005, Physical biology.
[27] H. Vogel,et al. Correlated Optical and Electrical Single‐Molecule Measurements Reveal Conformational Diffusion from Ligand Binding to Channel Gating in the Nicotinic Acetylcholine Receptor , 2011, Chembiochem : a European journal of chemical biology.
[28] M. Sansom,et al. Hydrophobic gating in ion channels. , 2015, Journal of molecular biology.
[29] J. Changeux. Protein dynamics and the allosteric transitions of pentameric receptor channels , 2014, Biophysical Reviews.
[30] Z. Luthey-Schulten,et al. Dynamical networks in tRNA:protein complexes , 2009, Proceedings of the National Academy of Sciences.
[31] J. Changeux,et al. Structure and pharmacology of pentameric receptor channels: from bacteria to brain. , 2012, Structure.
[32] Massimiliano Bonomi,et al. PLUMED: A portable plugin for free-energy calculations with molecular dynamics , 2009, Comput. Phys. Commun..
[33] Amanda L. Jonsson,et al. Ligand-dependent activation and deactivation of the human adenosine A(2A) receptor. , 2013, Journal of the American Chemical Society.
[34] Alexander D. MacKerell,et al. Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types. , 2010, The journal of physical chemistry. B.
[35] R. Dutzler,et al. Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel , 2009, Nature.
[36] David Calkins,et al. Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution , 2010, J. Comput. Aided Mol. Des..
[37] Rommie E. Amaro,et al. Weighted Implementation of Suboptimal Paths (WISP): An Optimized Algorithm and Tool for Dynamical Network Analysis , 2014, Journal of chemical theory and computation.
[38] Leo S. D. Caves,et al. Bio3d: an R package for the comparative analysis of protein structures , 2006, Bioinform..
[39] Massimiliano Bonomi,et al. Linking well-tempered metadynamics simulations with experiments. , 2010, Biophysical journal.
[40] Alexander D. MacKerell,et al. Automation of the CHARMM General Force Field (CGenFF) II: Assignment of Bonded Parameters and Partial Atomic Charges , 2012, J. Chem. Inf. Model..
[41] Maarten G. Wolf,et al. g_membed: Efficient insertion of a membrane protein into an equilibrated lipid bilayer with minimal perturbation , 2010, J. Comput. Chem..
[42] Antonín Pavelka,et al. CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures , 2012, PLoS Comput. Biol..
[43] Matthew P. Repasky,et al. Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. , 2004, Journal of medicinal chemistry.
[44] Anthony Auerbach,et al. Agonist activation of a nicotinic acetylcholine receptor , 2015, Neuropharmacology.
[45] G. Crooks,et al. WebLogo: a sequence logo generator. , 2004, Genome research.
[46] H. Stahlberg,et al. The Structure of the Mouse Serotonin 5-HT3 Receptor in Lipid Vesicles. , 2016, Structure.
[47] D. Bertrand,et al. Nicotinic acetylcholine receptors: from basic science to therapeutics. , 2013, Pharmacology & therapeutics.
[48] A. Smit,et al. Structural basis of ligand recognition in 5-HT3 receptors , 2012, EMBO reports.
[49] G. Hummer,et al. Drying transition in the hydrophobic gate of the GLIC channel blocks ion conduction. , 2012, Biophysical journal.
[50] Antoine Taly,et al. A gating mechanism of pentameric ligand-gated ion channels , 2013, Proceedings of the National Academy of Sciences.
[51] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[52] Ben M. Webb,et al. Comparative Protein Structure Modeling Using MODELLER , 2007, Current protocols in protein science.
[53] J. Walstab,et al. 5-HT(3) receptors: role in disease and target of drugs. , 2010, Pharmacology & therapeutics.
[54] J. Changeux,et al. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel , 2011, Nature.
[55] J. Changeux,et al. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation , 2009, Nature.
[56] Nadezhda T. Doncheva,et al. Topological analysis and interactive visualization of biological networks and protein structures , 2012, Nature Protocols.
[57] S. Lummis. 5-HT3 Receptors , 2012, The Journal of Biological Chemistry.
[58] A. R. Aricescu,et al. Crystal structure of a human GABAA receptor , 2014, Nature.
[59] M. Parrinello,et al. Well-tempered metadynamics: a smoothly converging and tunable free-energy method. , 2008, Physical review letters.
[60] N. Unwin. Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranes , 2013, Quarterly Reviews of Biophysics.
[61] E. Kirkness,et al. A cytoplasmic region determines single-channel conductance in 5-HT3 receptors , 2003, Nature.
[62] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[63] Peter M. Kasson,et al. GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit , 2013, Bioinform..
[64] Christopher G. Tate,et al. Overcoming barriers to membrane protein structure determination , 2011, Nature Biotechnology.
[65] J. P. Grossman,et al. Biomolecular simulation: a computational microscope for molecular biology. , 2012, Annual review of biophysics.
[66] S. Sine,et al. Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors , 1994, Neuron.
[67] K Schulten,et al. VMD: visual molecular dynamics. , 1996, Journal of molecular graphics.