Psoriatic Arthritis : A clinical challenge to Dermatologist and Orthopedist

Psoriasis is a skin disease that is accompanied by systemic inflammation and is one of the most common inflammatory disorders, estimated to effect between 1 and 3% of the population [1] . It is characterized by epidermal hyperproliferation and dermal inflammation. The etiology of psoriasis is unknown but genetic factors play a role. Psoriasis may begin at any age but has two peak periods of onset: between 15 and 25 and between 50 to 60 years of age. In many patients, psoriasis affects only a small area of the skin (<2% of body surface area) whereas in other patients, the disease can be quite severe, affecting a large portion of the skin. The cutaneous manifestations lead to considerable morbidity and the emotional burden of severe psoriasis has been shown to be similar to that seen in patients with cancer, diabetes, and heart disease.

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