A new high resolution color flow system using an eigendecomposition-based adaptive filter for clutter rejection

We present a new signal processing strategy for high frequency color flow mapping in moving tissue environments. A new application of an eigendecomposition-based clutter rejection filter is presented with modifications to deal with high blood-to-clutter ratios (BCR). Additionally, a new method for correcting blood velocity estimates with an estimated tissue motion profile is detailed. The performance of the clutter filter and velocity estimation strategies is quantified using a new swept-scan signal model. In vivo color flow images are presented to illustrate the potential of the system for mapping blood flow in the microcirculation with external tissue motion.

[1]  L. Thomas,et al.  An improved wall filter for flow imaging of low velocity flow , 1994, 1994 Proceedings of IEEE Ultrasonics Symposium.

[2]  B G Zagar,et al.  Ultrasonic mapping of the microvasculature: signal alignment. , 1998, Ultrasound in medicine & biology.

[3]  F. Stuart Foster,et al.  High-frequency color flow imaging of the microcirculation , 2000 .

[4]  M.E. Allam,et al.  Isomorphism between pulsed-wave Doppler ultrasound and direction-of-arrival estimation. I. Basic principles , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[5]  R.S.C. Cobbold,et al.  A new time-domain narrowband velocity estimation technique for Doppler ultrasound flow imaging. II. Comparative performance assessment , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[6]  G. R. Lockwood,et al.  Ultrasound backscatter from blood in the 30 to 70 MHz frequency range , 1994, 1994 Proceedings of IEEE Ultrasonics Symposium.

[7]  K. Kristoffersen,et al.  An extended autocorrelation method for estimation of blood velocity , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[8]  N. Bom,et al.  Ultrasound backscatter at 30 MHz from human blood: influence of rouleau size affected by blood modification and shear rate. , 1995, Ultrasound in medicine & biology.

[9]  G Cloutier,et al.  A point process approach to assess the frequency dependence of ultrasound backscattering by aggregating red blood cells. , 2001, The Journal of the Acoustical Society of America.

[10]  Alexander M. Haimovich,et al.  An eigenanalysis interference canceler , 1991, IEEE Trans. Signal Process..

[11]  H. Torp Clutter rejection filters in color flow imaging: a theoretical approach , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[12]  R. J. Fornaris,et al.  A swept-scanning mode for estimation of blood velocity in the microvasculature , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[13]  J. Greenleaf,et al.  Isomorphism between pulsed-wave Doppler ultrasound and direction-of-arrival estimation. II. Experimental results , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[14]  P. Strobach Low-rank adaptive filters , 1996, IEEE Trans. Signal Process..

[15]  H. Torp,et al.  The effect of accelerated tissue motion on clutter rejection in color flow imaging , 1999, 1999 IEEE Ultrasonics Symposium. Proceedings. International Symposium (Cat. No.99CH37027).

[16]  R. Silverman,et al.  High-resolution ultrasonic imaging of blood flow in the anterior segment of the eye. , 1999, Investigative ophthalmology & visual science.

[17]  K.W. Ferrara Effect of the beam-vessel angle on the received acoustic signal from blood , 1995, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[18]  C. Kasai,et al.  Real-Time Two-Dimensional Blood Flow Imaging Using an Autocorrelation Technique , 1985, IEEE Transactions on Sonics and Ultrasonics.

[19]  Steinar Bjaerum,et al.  Optimal adaptive clutter filtering in color flow imaging , 1997, 1997 IEEE Ultrasonics Symposium Proceedings. An International Symposium (Cat. No.97CH36118).

[21]  Optimization of real-time high frequency ultrasound for blood flow imaging in the microcirculation , 2000, 2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.00CH37121).

[22]  R. Silverman,et al.  Estimation of blood velocity with high frequency ultrasound , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[23]  Dimitris G. Manolakis,et al.  Statistical and Adaptive Signal Processing: Spectral Estimation, Signal Modeling, Adaptive Filtering and Array Processing , 1999 .

[24]  K. Shung,et al.  High frequency ultrasonic backscatter from erythrocyte suspension , 1994, IEEE Transactions on Biomedical Engineering.

[25]  K. Kristoffersen,et al.  Autocorrelation techniques in color flow imaging: signal model and statistical properties of the autocorrelation estimates , 1994, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[26]  A. Haimovich,et al.  The eigencanceler: adaptive radar by eigenanalysis methods , 1996, IEEE Transactions on Aerospace and Electronic Systems.

[27]  R.S.C. Cobbold,et al.  A new time-domain narrowband velocity estimation technique for Doppler ultrasound flow imaging. I. Theory , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.