Correlates of Informant-Rated Cognitive Decline after Stroke

Cognitive impairment is common after stroke, but measurement is problematic. Six tests of mental ability, unaffected by loss of limb function, were administered to 49 subjects of mean age 74.2 years at a median of 4.3 years (range 0.1–16.8) after stroke together with a depression score and the IQCODE, an informant-rated scale of estimated cognitive decline. Over 90% of stroke patients were able to complete most tests. IQCODE correlated significantly with the HADS depression score (r = 0.35, p = 0.040), the 2-year Barthel score (r = –0.60, p = 0.001) and with a general cognitive factor extracted from the mental ability test scores (r = –0.42, p = 0.016). We conclude that informant-rated methods offer a promising approach to measuring cognitive decline after stroke.

[1]  F Doyon,et al.  [Evaluation of diagnostic methods]. , 2001, Journal de radiologie.

[2]  I. Deary,et al.  Fluid intelligence, memory and blood pressure in cognitive aging , 1998 .

[3]  D. Leys,et al.  Preexisting dementia in stroke patients. Baseline frequency, associated factors, and outcome. , 1997, Stroke.

[4]  J. Desmond,et al.  Neural Substrates of Fluid Reasoning: An fMRI Study of Neocortical Activation during Performance of the Raven's Progressive Matrices Test , 1997, Cognitive Psychology.

[5]  W. Gordon,et al.  Poststroke depression: an examination of the literature. , 1997, Archives of physical medicine and rehabilitation.

[6]  J. D. de Jonghe.  DIFFERENTIATING BETWEEN DEMENTED AND PSYCHIATRIC PATIENTS WITH THE DUTCH VERSION OF THE IQCODE , 1997, International journal of geriatric psychiatry.

[7]  M Prencipe,et al.  Stroke, disability, and dementia: results of a population survey. , 1997, Stroke.

[8]  E. Feskens,et al.  Cerebrovascular disease, the apolipoprotein e4 allele, and cognitive decline in a community-based study of elderly men. , 1996, Stroke.

[9]  B. Cesana,et al.  Dementia after first stroke. , 1996, Stroke.

[10]  Anthony F Jorm,et al.  Further data on the validity of the informant questionnaire on cognitive decline in the elderly (IQCODE) , 1996 .

[11]  V. Hachinski,et al.  Vascular cognitive impairment: a new approach to vascular dementia. , 1995, Bailliere's clinical neurology.

[12]  L. Bentzen,et al.  Rehabilitation after stroke: predictive power of Barthel Index versus a cognitive and a motor index , 1995, Acta neurologica Scandinavica.

[13]  U. Hadar,et al.  Cognition in stroke , 1994, Acta neurologica Scandinavica.

[14]  R. Robinson,et al.  Longitudinal Assessment of Depression and Cognitive Impairment Following Stroke , 1994, The Journal of nervous and mental disease.

[15]  Anthony F Jorm.  A short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): development and cross-validation , 1994, Psychological Medicine.

[16]  A. Baddeley,et al.  The Spot-the-Word test: a robust estimate of verbal intelligence based on lexical decision. , 1993, The British journal of clinical psychology.

[17]  Y. Stern,et al.  Risk factors for cerebrovascular disease as correlates of cognitive function in a stroke-free cohort. , 1993, Archives of neurology.

[18]  L. Whalley,et al.  The quantification of the relative effects of age and NART‐predicted IQ on cognitive function in healthy old people , 1992 .

[19]  H. Christensen,et al.  Short report: Effect of premorbid intelligence on the Mini‐Mental State and IQCODE , 1992 .

[20]  Anthony F Jorm,et al.  The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): socio-demographic correlates, reliability, validity and some norms , 1989, Psychological Medicine.

[21]  D. M. Parker,et al.  Prediction of WAIS IQ with the National Adult Reading Test: Cross‐validation and extension , 1989 .

[22]  D. M. Parker,et al.  The relationship between demographic variables and NART performance in normal subjects. , 1988, The British journal of clinical psychology.

[23]  J. Langston,et al.  The Neurobehavioral Cognitive Status Examination: a brief but quantitative approach to cognitive assessment. , 1987, Annals of internal medicine.

[24]  C D Marsden,et al.  Mini-mental state examination in neurological patients. , 1984, Journal of neurology, neurosurgery, and psychiatry.

[25]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[26]  R. Likert,et al.  The revised Minnesota paper form board test. , 1937 .

[27]  Y. Stern,et al.  Dementia as a predictor of adverse outcomes following stroke: an evaluation of diagnostic methods. , 1998, Stroke.

[28]  C. Herrmann.  International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results. , 1997, Journal of psychosomatic research.

[29]  R. Jacoby,et al.  Cognitive impairment in medical inpatients. I: Screening for dementia--is history better than mental state? , 1997, Age and ageing.

[30]  Anthony F Jorm.  Assessment of cognitive impairment and dementia using informant reports , 1996 .

[31]  D. W. Desmond,et al.  Vascular dementia: a construct in evolution. , 1996, Cerebrovascular and brain metabolism reviews.

[32]  R. O'Carroll.  The Assessment of premorbid ability: A critical review , 1995 .

[33]  I. Deary,et al.  Which abilities does the PASAT test , 1991 .

[34]  G. Huston.  The Hospital Anxiety and Depression Scale. , 1987, The Journal of rheumatology.

[35]  T. Hammeke,et al.  The Luria-Nebraska neuropsychological battery : a manual for clinical and experimental uses , 1979 .

[36]  R. Reitan,et al.  Clinical neuropsychology: Current status and applications. , 1974 .

[37]  J. Raven,et al.  Manual for Raven's progressive matrices and vocabulary scales , 1962 .