CASE OF HEMORRHAGE FROM A DUODENAL DIVERTICULUM TREATED SUCCESSFULLY BY ENDOSCOPIC INJECTIONS OF EPINEPHRINE

Although duodenal diverticula are found relatively frequently in adult gastrointestinal tracts, the majority are asymptomatic. We report a case of duodenal diverticulum complicated with hemorrhage. A 74‐year‐old woman developed hematemesis and tarry stools. An emergent upper gastrointestinal endoscopy revealed a diverticulum, about 3 cm in diameter, in the posteromedial aspect of the second duodenal segment, right oral to the papilla. The diverticulum was filled with blood clots. After removing them by gentle suction, a linear ulcer became visible and an actively oozing site was seen at one edge of the ulcer. Three injections of epinephrine in a 2.5% sodium chloride solution (epinephrine concentration 0.05 mg/mL), each 1.0 mL for a total volume of 3.0 mL, were made at the oozing site. The exuding ceased immediately after the third injection and bleeding did not reappear. In our patient, successful and complete hemostasis was obtained by this endoscopic injection of epinephrine, although most cases of duodenal diverticulum complicated with hemorrhage had been treated surgically. We think that endoscopic, instead of surgical treatment is considerably becoming another choice for treating patients with a bleeding duodenal diverticulum.

[1]  H. Fukui,et al.  A CASE OF HEMORRHAGE FROM THE DUODENAL DIVERTICULUM TREATED BY ENDOSCOPIC LOCAL INJECTION THERAPY WITH HYPERTONIC SALINE EPINEPHRINE SOLUTION , 2000 .

[2]  L. S. Wong,et al.  Duodenal diverticulum as a cause of massive gastrointestinal bleeding , 1999, Journal of the Royal Society of Medicine.

[3]  T. Morita,et al.  Massive bleeding from the Duodenal Diverticulum : A Case Report and Review of the Literature in Japan , 1999 .

[4]  A. Irisawa,et al.  SUCCESSFUL HEMOSTASIS OF A BLEEDING DUODENAL DIVERTICULUM BY ENDOSCOPIC INJECTION OF AETHOXYSKLEROL , 1998 .

[5]  S. Rogers,et al.  Endoscopic management of hemorrhage from a duodenal diverticulum. , 1998, Gastrointestinal endoscopy.

[6]  H. Itoh,et al.  A CASE OF HEMORRHAGE FROM AN INTRADIVERTICULUR ULCER INTHE SECOND PORTION OF THE DUODENUM TREATED BY ENDOSCOPIC INJECTION , 1998 .

[7]  F. Mosimann,et al.  The duodenal diverticulum: an exceptional site of massive bleeding. , 1998, Hepato-gastroenterology.

[8]  Y. Morishita,et al.  DUODENAL DIVERTICULUM WITH MASSIVE BLEEDING-A CASE REPORT WITH SURGICAL TREATMENT- , 1997 .

[9]  A. Gangl,et al.  No evidence of activated blood coagulation in Crohn's disease , 1997, European journal of gastroenterology & hepatology.

[10]  Toshio Shimizu,et al.  A CASE OF INTERMITTENT AND REPEATED HEMORRAGE FROM DUODENAL DIVERTICULUM , 1997 .

[11]  A. Gangl,et al.  The relationship between juxtapapillary duodenal diverticula and biliary stone disease , 1997, European journal of gastroenterology & hepatology.

[12]  S. Des Groseilliers,et al.  Massive upper gastrointestinal bleeding originating from a fourth-stage duodenal diverticulum: a case report and review of the literature. , 1996, Canadian journal of surgery. Journal canadien de chirurgie.

[13]  T. Hibi,et al.  ACASE OF HEMORRHAGE FROM INTRADIVERTICULUR ULCER IN THEI SECOND PORTION OF DUODENUM TREATED WITH ENDOSCOPIC INJECTION THERAPY , 1996 .

[14]  G. Haber,et al.  Endoscopic therapy of a bleeding duodenal diverticulum. , 1995, The American journal of gastroenterology.

[15]  L. D. Leffall,et al.  Massive upper gastrointestinal bleeding in a patient with a duodenal diverticulum: a case report and review of the literature. , 1992, Journal of the National Medical Association.

[16]  J. Isaac,et al.  Endoscopic management of a bleeding duodenal diverticulum. , 1991, Gastrointestinal endoscopy.

[17]  H. Yamabe,et al.  A CASE OF MASSIVE BLEEDING FROM THE DUODENAL DIVERTICULUM , 1991 .

[18]  H. Hasegawa,et al.  A CASE OF PLEOMORPHIC CARCINOMA OF THE PANCREAS WITH INTRADIVERTICULAR BLEEDING OF THE DUODENUM , 1990 .

[19]  R. Cattell,et al.  The surgical significance of duodenal diverticula. , 1952, The New England journal of medicine.

[20]  北澤利幸 高張ナトリウムエピネフリン液 (HSE) 局注療法が有用であった十二指腸憩室出血の1例 , 2000 .

[21]  S. Tanabe,et al.  Endoscopic Hemostasis Using Clip for a Bleeding Duodenal Diverticulum , 1995 .

[22]  H. Tanabe,et al.  Diagnostic Usefulness of Scintigram for Gastrointestinal Bleeding in a Case of Massive Hemorrhage from Duodenal Diverticulum. , 1993 .

[23]  T. Kihara,et al.  A Case Report of Duodenal Deverticulum with Massive Hemorrhage -with Incidence of Duodenal Diverticula at X-ray Examinations- , 1993 .

[24]  K. Ogawa,et al.  A case report of the duodenal diverticulum with massive hemorrhage. , 1989 .