An accurate and interpretable model for BCCT.core

Breast Cancer Conservative Treatment (BCCT) is considered nowadays to be the most widespread form of locor-regional breast cancer treatment. However, aesthetic results are heterogeneous and difficult to evaluate in a standardized way. The limited reproducibility of subjective aesthetic evaluation in BCCT motivated the research towards objective methods. A recent computer system (BCCT.core) was developed to objectively and automatically evaluate the aesthetic result of BCCT. The system is centered on a support vector machine (SVM) classifier with a radial basis function (RBF) used to predict the overall cosmetic result from features computed on a digital photograph of the patient. However, this classifier is not ideal for the interpretation of the factors being used in the prediction. Therefore, an often suggested improvement is the interpretability of the model being used to assess the overall aesthetic result. In the current work we investigate the accuracy of different interpretable methods against the model currently deployed in the BCCT.core software. We compare the performance of decision trees and linear classifiers with the RBF SVM currently in BCCT.core. In the experimental study, these interpretable models shown a similar accuracy to the currently used RBF SVM, suggesting that the later can be replaced without sacrificing the performance of the BCCT.core.

[1]  Tomas Kron,et al.  A comparison of methods of cosmetic assessment in breast conservation treatment , 1996 .

[2]  Isabelle Guyon,et al.  An Introduction to Variable and Feature Selection , 2003, J. Mach. Learn. Res..

[3]  Maria João Cardoso,et al.  Interobserver agreement and consensus over the esthetic evaluation of conservative treatment for breast cancer. , 2006, Breast.

[4]  E van der Schueren,et al.  Cosmetic evaluation of breast conserving treatment for mammary cancer. 1. Proposal of a quantitative scoring system. , 1989, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[5]  R W Blamey,et al.  The cosmetic outcome in early breast cancer treated with breast conservation. , 1999, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[6]  Jaime S. Cardoso,et al.  Breast Contour Detection with Stable Paths , 2008, BIOSTEC.

[7]  Jaime S. Cardoso,et al.  Automatic Breast Contour Detection in Digital Photographs , 2008, HEALTHINF.

[8]  Jaime S. Cardoso,et al.  Towards an intelligent medical system for the aesthetic evaluation of breast cancer conservative treatment , 2007, Artif. Intell. Medicine.

[9]  J O Archambeau,et al.  Breast retraction assessment: an objective evaluation of cosmetic results of patients treated conservatively for breast cancer. , 1985, International journal of radiation oncology, biology, physics.

[10]  Christopher M. Bishop,et al.  Pattern Recognition and Machine Learning (Information Science and Statistics) , 2006 .

[11]  Jaime S. Cardoso,et al.  Learning to Classify Ordinal Data: The Data Replication Method , 2007, J. Mach. Learn. Res..