Title: The DegraBase: a database of proteolysis in healthy and apoptotic human cells Running Title: DegraBase: A Human α-aminome database

1! Title: The DegraBase: a database of proteolysis in healthy and apoptotic human cells Running Title: DegraBase: A Human α-aminome database Authors: Emily D. Crawford*1,2, Julia E. Seaman*1, Nick Agard1,3, Gerald W. Hsu1,4, Olivier Julien1, Sami Mahrus1,5, Huy Nguyen1,6, Kazutaka Shimbo1,7, Hikari A. I. Yoshihara1,8, Min Zhuang1, Robert J. Chalkley1, James A. Wellsǂ1,9 *Authors contributed equally to this work ǂ To whom correspondence should be addressed Institutions: 1Department of Pharmaceutical Chemistry, UCSF, San Francisco, 94158 2Present address: DZNE, German Center for Neurodegenerative Diseases, D-72076 Tubingen, Germany. 3Present address: Department of Biocatalyst Characterization and Design, Codexis; Redwood City, CA 94063 4Present address: Dept. of Medicine, San Francisco VAMC, 4150 Clement Street, San Francisco, CA 94121 5Present address: Department of Oncology Biomarker Development, Genentech, South San Francisco, CA 94080 6Present address: Department of Hematology and Oncology, Kaiser Permanente, Honolulu, HI 96819 7Present address: Institute For Innovations, Ajinomoto Co., Inc., 1-1 Suzuki-Cho, KawasakiKu, Kawasaki-Shi. 210-8681 Japan 8Present address: Centre Hospitalier Universitaire Vaudois (CHUV), EPFL SB IPSB GR-CO, CH F1 592 (Bâtiment CH), Station 6, CH-1015 Lausanne, Switzerland 9Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, 94158 MCP Papers in Press. Published on December 20, 2012 as Manuscript O112.024372

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