Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease

[1]  A. McKnight,et al.  DNA Methylation Associated With Diabetic Kidney Disease in Blood-Derived DNA , 2020, Frontiers in Cell and Developmental Biology.

[2]  J. Florez,et al.  Genetics of diabetes mellitus and diabetes complications , 2020, Nature Reviews Nephrology.

[3]  W. Evans,et al.  ARID5B Influences Antimetabolite Drug Sensitivity and Prognosis of Acute Lymphoblastic Leukemia , 2019, Clinical Cancer Research.

[4]  Angelo J. Canty,et al.  Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. , 2019, Journal of the American Society of Nephrology : JASN.

[5]  Liang Liang,et al.  Prognosis of clear cell renal cell carcinoma (ccRCC) based on a six-lncRNA-based risk score: an investigation based on RNA-sequencing data , 2019, Journal of Translational Medicine.

[6]  R. Krediet,et al.  Long-term peritoneal dialysis treatment provokes activation of genes related to adaptive immunity. , 2019, Physiological research.

[7]  Baofeng Lian,et al.  The analysis of risk factors for diabetic nephropathy progression and the construction of a prognostic database for chronic kidney diseases , 2019, Journal of Translational Medicine.

[8]  N. Yang,et al.  Pim‐1 as a Therapeutic Target in Lupus Nephritis , 2019, Arthritis & rheumatology.

[9]  K. Westover,et al.  Intergrated analysis of ELMO1, serves as a link between tumour mutation burden and epithelial-mesenchymal transition in hepatocellular carcinoma , 2019, EBioMedicine.

[10]  M. Luppi,et al.  T-cell large granular lymphocyte leukemia in solid organ transplant recipients: case series and review of the literature , 2019, International journal of hematology.

[11]  Hongzhe Li,et al.  Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease , 2019, Nature Communications.

[12]  D. Tenen,et al.  The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia. , 2019, Blood.

[13]  Mitsuo Kato,et al.  Epigenetics and epigenomics in diabetic kidney disease and metabolic memory , 2019, Nature Reviews Nephrology.

[14]  Hongbing Shen,et al.  Identification of Novel T1D Risk Loci and Their Association With Age and Islet Function at Diagnosis in Autoantibody-Positive T1D Individuals: Based on a Two-Stage Genome-Wide Association Study , 2019, Diabetes Care.

[15]  C. Gieger,et al.  Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk , 2019, Proceedings of the National Academy of Sciences.

[16]  J. Mill,et al.  Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array , 2019, BMC Genomics.

[17]  Weihong Cao,et al.  PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation , 2019, Breast cancer.

[18]  Wei Zhang,et al.  Selective inhibition of class IIa histone deacetylases alleviates renal fibrosis , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  Chao-Yan Sun,et al.  Associations between Vitamin D and β-Cell Function and Colorectal Cancer-Associated Tumor Markers in Chinese Type 2 Diabetic Patients with Albuminuria. , 2019, Clinical laboratory.

[20]  Safa Al-Sarraj,et al.  Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease , 2019, Clinical Epigenetics.

[21]  Suman Lee,et al.  The association of genetically controlled CpG methylation (cg158269415) of protein tyrosine phosphatase, receptor type N2 (PTPRN2) with childhood obesity , 2019, Scientific Reports.

[22]  Y. Huang,et al.  Renal cell carcinoma: predicting RUNX3 methylation level and its consequences on survival with CT features , 2019, European Radiology.

[23]  T. Wong,et al.  Association of Diabetic Retinopathy and Diabetic Kidney Disease With All-Cause and Cardiovascular Mortality in a Multiethnic Asian Population , 2019, JAMA network open.

[24]  Saijuan Chen,et al.  TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy , 2019, Cell Death & Differentiation.

[25]  P. Ismail,et al.  Association of CCL2, CCR5, ELMO1, and IL8 Polymorphism with Diabetic Nephropathy in Malaysian Type 2 Diabetic Patients , 2019, International journal of chronic diseases.

[26]  Michael R. Elliott,et al.  A non-canonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis , 2018, Nature Immunology.

[27]  Damian Szklarczyk,et al.  STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets , 2018, Nucleic Acids Res..

[28]  M. Seidl,et al.  Characterization of septin expression in normal and fibrotic kidneys , 2018, Cytoskeleton.

[29]  R. Baybutt,et al.  Cux1 regulation of the cyclin kinase inhibitor p27kip1 in polycystic kidney disease is attenuated by HDAC inhibitors. , 2019, Gene.

[30]  A. McKnight,et al.  Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches , 2018, BMC Research Notes.

[31]  Yu Deng,et al.  Pim1 promotes cell proliferation and regulates glycolysis via interaction with MYC in ovarian cancer , 2018, OncoTargets and therapy.

[32]  G. Anton,et al.  Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome , 2018, Journal of immunology research.

[33]  A. Advani,et al.  Histone Deacetylase Inhibitors and Diabetic Kidney Disease , 2018, International journal of molecular sciences.

[34]  W. McArdle,et al.  Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes. , 2018, Journal of autoimmunity.

[35]  J. Dodd,et al.  Metformin and Dietary Advice for Pregnant Women Who Are Overweight or Obese to Promote Gestational Restriction of Weight—The GROW Randomized Trial , 2018, Diabetes.

[36]  S. Golden,et al.  Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5 , 2018, Clinical Epigenetics.

[37]  M. McNerney,et al.  Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS. , 2018, Blood.

[38]  R. Hanson,et al.  Cytosine methylation predicts renal function decline in American Indians. , 2018, Kidney international.

[39]  Lili Yu,et al.  PBX1 promotes the cell proliferation via JAK2/STAT3 signaling in clear cell renal carcinoma. , 2018, Biochemical and biophysical research communications.

[40]  M. McCarthy,et al.  A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes , 2018, Diabetes.

[41]  J. Mao,et al.  PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis , 2018, Cell Death & Disease.

[42]  L. Canani,et al.  The rs2292239 polymorphism in ERBB3 gene is associated with risk for type 1 diabetes mellitus in a Brazilian population. , 2018, Gene.

[43]  Matthias Kretzler,et al.  A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome. , 2017, Kidney international.

[44]  L. Dimeglio,et al.  Type 1 Diabetes , 2019, Epidemiology of Diabetes.

[45]  T. Mahjoub,et al.  Gender differences in the association of ELMO1 genetic variants with type 2 diabetes in Tunisian Arabs , 2018, Journal of Endocrinological Investigation.

[46]  F. Pociot Type 1 diabetes genome-wide association studies: not to be lost in translation , 2017, Clinical & translational immunology.

[47]  Audrey Y. Chu,et al.  Epigenome-wide association studies identify DNA methylation associated with kidney function , 2017, Nature Communications.

[48]  R. Leslie,et al.  The Role of Epigenetics in Type 1 Diabetes , 2017, Current Diabetes Reports.

[49]  R. Baybutt,et al.  Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model. , 2017, American journal of physiology. Renal physiology.

[50]  S. Miyano,et al.  Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype , 2017, Oncology letters.

[51]  A. Bansal,et al.  DNA methylation and its role in the pathogenesis of diabetes , 2017, Pediatric diabetes.

[52]  Sassan Noazin,et al.  Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies , 2017, Oncotarget.

[53]  F. Béna,et al.  PBX1 haploinsufficiency leads to syndromic congenital anomalies of the kidney and urinary tract (CAKUT) in humans , 2017, Journal of Medical Genetics.

[54]  M. McCarthy,et al.  The Genetic Landscape of Renal Complications in Type 1 Diabetes. , 2017, Journal of the American Society of Nephrology : JASN.

[55]  Taotao Ma,et al.  Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis , 2017, Toxicology and applied pharmacology.

[56]  René A. M. Dirks,et al.  Genome-wide epigenomic profiling for biomarker discovery , 2016, Clinical Epigenetics.

[57]  A. Just,et al.  Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood , 2016, Clinical Epigenetics.

[58]  Pao-Yang Chen,et al.  Profiling genome-wide DNA methylation , 2016, Epigenetics & Chromatin.

[59]  H. Kędzierska,et al.  Expression of Genes Involved in Cellular Adhesion and Extracellular Matrix Remodeling Correlates with Poor Survival of Patients with Renal Cancer. , 2016, The Journal of urology.

[60]  E. Svarstad,et al.  One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease , 2016, PloS one.

[61]  S. Ropero,et al.  Development of Castration Resistant Prostate Cancer can be Predicted by a DNA Hypermethylation Profile. , 2016, The Journal of urology.

[62]  Junnian Zheng,et al.  The emerging role of RUNX3 in cancer metastasis (Review). , 2016, Oncology reports.

[63]  E. Binder,et al.  Gene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications , 2016, Neuropsychopharmacology.

[64]  E. Ziętkiewicz,et al.  Impact of SNPs on methylation readouts by Illumina Infinium HumanMethylation450 BeadChip Array: implications for comparative population studies , 2015, BMC Genomics.

[65]  A. Maxwell,et al.  Distinct methylation patterns in genes that affect mitochondrial function are associated with kidney disease in blood‐derived DNA from individuals with Type 1 diabetes , 2015, Diabetic medicine : a journal of the British Diabetic Association.

[66]  A. Schäffer,et al.  Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA‐2, IA‐2β, and GAD65 , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[67]  Alan B Leichtman,et al.  US Renal Data System 2014 Annual Data Report: Epidemiology of Kidney Disease in the United States. , 2015, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[68]  M. Mauer,et al.  Glomerular structural-functional relationship models of diabetic nephropathy are robust in type 1 diabetic patients. , 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[69]  S. Zhuang,et al.  Treatment of chronic kidney diseases with histone deacetylase inhibitors , 2015, Front. Physiol..

[70]  T. George,et al.  BCL6 expression correlates with the t(1;19) translocation in B-lymphoblastic leukemia. , 2015, American journal of clinical pathology.

[71]  V. Galkin,et al.  Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility , 2014, The Journal of cell biology.

[72]  A. McKnight,et al.  Genetic and epigenetic factors influencing chronic kidney disease. , 2014, American journal of physiology. Renal physiology.

[73]  Teruhiko Yoshida,et al.  Comprehensive Exploration of Novel Chimeric Transcripts in Clear Cell Renal Cell Carcinomas Using Whole Transcriptome Analysis , 2014, Genes, chromosomes & cancer.

[74]  Katalin Susztak,et al.  Molecular mechanisms of diabetic kidney disease. , 2014, The Journal of clinical investigation.

[75]  H. Falhammar,et al.  Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy , 2014, Clinical Epigenetics.

[76]  A. McKnight,et al.  DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease , 2014, Epigenetics.

[77]  Elin Hall,et al.  Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion , 2014, PLoS genetics.

[78]  G. Qin,et al.  HDAC4: mechanism of regulation and biological functions. , 2014, Epigenomics.

[79]  N. Rajakumar,et al.  The effects of olanzapine on genome-wide DNA methylation in the hippocampus and cerebellum , 2014, Clinical Epigenetics.

[80]  J. Hirschhorn,et al.  Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes. , 2013, Journal of the American Society of Nephrology : JASN.

[81]  R. Hanson,et al.  Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes , 2013, Diabetes.

[82]  B. Kasiske,et al.  Angiotensin II blockade in kidney transplant recipients. , 2013, Journal of the American Society of Nephrology : JASN.

[83]  P. Pozzilli,et al.  Epigenetics in autoimmune diseases with focus on type 1 diabetes , 2013, Diabetes/metabolism research and reviews.

[84]  L. Li,et al.  Association of ELMO1 gene polymorphisms with diabetic nephropathy in Chinese population , 2013, Journal of Endocrinological Investigation.

[85]  David Staudt,et al.  Uncovering the molecular and cellular mechanisms of heart development using the zebrafish. , 2012, Annual review of genetics.

[86]  P. Marquet,et al.  Association of sirolimus adverse effects with m-TOR, p70S6K or Raptor polymorphisms in kidney transplant recipients , 2012, Pharmacogenetics and genomics.

[87]  M. Horikoshi,et al.  Associations of variations in the MRF2/ARID5B gene with susceptibility to type 2 diabetes in the Japanese population , 2012, Journal of Human Genetics.

[88]  Benjamin J. Keller,et al.  New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes , 2012, PLoS genetics.

[89]  Devin C. Koestler,et al.  DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.

[90]  Eric Meggers,et al.  PIM1 kinase as a target for cancer therapy , 2012, Expert opinion on investigational drugs.

[91]  Junnian Zheng,et al.  RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration , 2011, Journal of Cancer Research and Clinical Oncology.

[92]  B. Najafian,et al.  Quantitating Glomerular Endothelial Fenestration: An Unbiased Stereological Approach , 2011, American Journal of Nephrology.

[93]  B. Molnár,et al.  The Influence of Methylated Septin 9 Gene on RNA and Protein Level in Colorectal Cancer , 2011, Pathology & Oncology Research.

[94]  R. Reeves,et al.  Why target PIM1 for cancer diagnosis and treatment? , 2010, Future oncology.

[95]  D. Chasman,et al.  Multiple new genetic loci associated with kidney function and Chronic Kidney Disease: The CKDGen Consortium , 2010 .

[96]  Stephan Beck,et al.  Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus , 2010, BMC Medical Genomics.

[97]  Uwe Völker,et al.  New loci associated with kidney function and chronic kidney disease , 2010, Nature Genetics.

[98]  J. Kaldor,et al.  Effect of reduced immunosuppression after kidney transplant failure on risk of cancer: population based retrospective cohort study , 2010, BMJ : British Medical Journal.

[99]  H. Yoshida,et al.  Association of genetic variants with chronic kidney disease in Japanese individuals with or without hypertension or diabetes mellitus. , 2010, Experimental and therapeutic medicine.

[100]  E. Binder The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders , 2009, Psychoneuroendocrinology.

[101]  Samy Suissa,et al.  Renal and retinal effects of enalapril and losartan in type 1 diabetes. , 2009, The New England journal of medicine.

[102]  J. Gécz,et al.  A UPF3-mediated regulatory switch that maintains RNA surveillance , 2009, Nature Structural &Molecular Biology.

[103]  G. Chaturvedi,et al.  The homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expression during kidney development. , 2009, Gene.

[104]  Stephen S. Rich,et al.  Genome-Wide Association Scan for Diabetic Nephropathy Susceptibility Genes in Type 1 Diabetes , 2009, Diabetes.

[105]  M. Rastaldi,et al.  Enhanced Expression of Janus Kinase–Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy , 2009, Diabetes.

[106]  B. Balkau,et al.  Evaluating the association of common APOA2 variants with type 2 diabetes , 2008, BMC Medical Genetics.

[107]  B. Balkau,et al.  Evaluating the association of common PBX1 variants with type 2 diabetes , 2008, BMC Medical Genetics.

[108]  Christine A. Orengo,et al.  Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint , 2007, BMC Bioinformatics.

[109]  J. Kaldor,et al.  Cancer incidence before and after kidney transplantation. , 2006, JAMA.

[110]  Felix Eichinger,et al.  Modular Activation of Nuclear Factor-κB Transcriptional Programs in Human Diabetic Nephropathy , 2006, Diabetes.

[111]  R. Klein,et al.  The relationship of diabetic retinopathy to preclinical diabetic glomerulopathy lesions in type 1 diabetic patients: the Renin-Angiotensin System Study. , 2005, Diabetes.

[112]  A. Pestronk,et al.  Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein , 2004, Nature Genetics.

[113]  Nunzio Bottini,et al.  A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes , 2004, Nature Genetics.

[114]  D. Gutsch,et al.  Effect of DNA methylation and chromatin structure on ITGAL expression. , 2002, Blood.

[115]  Michael E. Miller,et al.  Cellular basis of diabetic nephropathy: 1. Study design and renal structural-functional relationships in patients with long-standing type 1 diabetes. , 2002, Diabetes.

[116]  C. Bogardus,et al.  Analysis of PBX1 as a candidate gene for type 2 diabetes mellitus in Pima Indians. , 2001, Biochimica et biophysica acta.

[117]  M. Mauer,et al.  Diabetic nephropathy as a model of reversibility of established renal lesions. , 1998, Current opinion in nephrology and hypertension.

[118]  José Costa,et al.  PicoGreen quantitation of DNA: effective evaluation of samples pre- or post-PCR , 1996, Nucleic Acids Res..

[119]  Shirley A. Miller,et al.  A simple salting out procedure for extracting DNA from human nucleated cells. , 1988, Nucleic acids research.