Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence

[1]  G. Mills,et al.  Multiplex digital spatial profiling of proteins and RNA in fixed tissue , 2020, Nature Biotechnology.

[2]  Russell J. Dickson,et al.  Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials , 2019, Front. Oncol..

[3]  Y. Lou,et al.  Next generation of immune checkpoint therapy in cancer: new developments and challenges , 2018, Journal of Hematology & Oncology.

[4]  Salil S. Bhate,et al.  Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging , 2017, Cell.

[5]  Kevin W. Eliceiri,et al.  ImageJ2: ImageJ for the next generation of scientific image data , 2017, BMC Bioinformatics.

[6]  Peter Bankhead,et al.  QuPath: Open source software for digital pathology image analysis , 2017, Scientific Reports.

[7]  R. Levenson,et al.  Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging , 2015, Laboratory Investigation.

[8]  Chichung Wang,et al.  Multiplexed immunohistochemistry, imaging, and quantitation: a review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis. , 2014, Methods.

[9]  Sean C. Bendall,et al.  Multiplexed ion beam imaging of human breast tumors , 2014, Nature Medicine.

[10]  Kevin W Eliceiri,et al.  NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.

[11]  R. Schreiber,et al.  Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion , 2011, Science.

[12]  C. Rueden,et al.  Metadata matters: access to image data in the real world , 2010, The Journal of cell biology.

[13]  P Komminoth,et al.  Amplification Methods to Increase the Sensitivity of In Situ Hybridization: Play CARD(S) , 1999, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[14]  T. Harris,et al.  Catalyzed reporter deposition, a novel method of signal amplification. Application to immunoassays. , 1989, Journal of immunological methods.

[15]  S. Downing,et al.  The InSituPlex® Staining Method for Multiplexed Immunofluorescence Cell Phenotyping and Spatial Profiling of Tumor FFPE Samples. , 2020, Methods in molecular biology.

[16]  J. Galon,et al.  Phenotyping of tumor infiltrating immune cells using mass-cytometry (CyTOF). , 2020, Methods in enzymology.

[17]  J. Beechem.  High-Plex Spatially Resolved RNA and Protein Detection Using Digital Spatial Profiling: A Technology Designed for Immuno-oncology Biomarker Discovery and Translational Research. , 2020, Methods in molecular biology.

[18]  T. Lumley,et al.  gplots: Various R Programming Tools for Plotting Data , 2015 .

[19]  Hisataka Kobayashi,et al.  Multiplexing with multispectral imaging: from mice to microscopy. , 2008, ILAR journal.