Foxo transcription factors control regulatory T cell development and function.
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Daniel R. Beisner | E. Stone | S. Hedrick | Irene L. Ch’en | Y. Kerdiles | M. McGargill | C. Stockmann | C. Katayama | Maureen A. McGargill
[1] R. DePinho,et al. Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells , 2010, Nature Immunology.
[2] Trey Ideker,et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates the B cell fate , 2010, Nature Immunology.
[3] R. DePinho,et al. Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells , 2010, The Journal of experimental medicine.
[4] A. Rudensky,et al. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate , 2010, Nature.
[5] E. Unanue,et al. CTLA-4 suppresses the pathogenicity of self antigen–specific T cells by cell-intrinsic and cell-extrinsic mechanisms , 2010, Nature Immunology.
[6] M. Linterman,et al. Signals that influence T follicular helper cell differentiation and function , 2010, Seminars in Immunopathology.
[7] Philippe P Roux,et al. mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling , 2009, Molecular and Cellular Biology.
[8] Caiying Guo,et al. T cells require Foxo1 to populate the peripheral lymphoid organs , 2009, European journal of immunology.
[9] Y. Wan,et al. How diverse--CD4 effector T cells and their functions. , 2009, Journal of molecular cell biology.
[10] S. Hedrick. The cunning little vixen: Foxo and the cycle of life and death , 2009, Nature Immunology.
[11] P. Worley,et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. , 2009, Immunity.
[12] Linda Mark,et al. Follicular helper T cells as cognate regulators of B cell immunity. , 2009, Current opinion in immunology.
[13] A. Rudensky,et al. Control of regulatory T cell lineage commitment and maintenance. , 2009, Immunity.
[14] Daniel R. Beisner,et al. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. , 2009, Nature immunology.
[15] K. Hogquist,et al. Thymic emigration: Sphingosine‐1‐phosphate receptor‐1‐dependent models and beyond , 2009, European journal of immunology.
[16] R. Flavell,et al. An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance. , 2009, Immunity.
[17] R. Friedline,et al. CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance , 2009, The Journal of experimental medicine.
[18] Daniel R. Beisner,et al. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor , 2009, Nature Immunology.
[19] P. Opolon,et al. Prevention of autoimmunity and control of recall response to exogenous antigen by Fas death receptor ligand expression on T cells. , 2008, Immunity.
[20] S. Hedrick,et al. The Erk2 MAPK Regulates CD8 T Cell Proliferation and Survival1 , 2008, The Journal of Immunology.
[21] V. Lazar,et al. FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase1 , 2008, The Journal of Immunology.
[22] V. Kuchroo,et al. TGF-β signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis , 2008, Proceedings of the National Academy of Sciences.
[23] D. Olive,et al. ICOS Ligation Recruits the p50α PI3K Regulatory Subunit to the Immunological Synapse1 , 2008, The Journal of Immunology.
[24] K. Shokat,et al. T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR , 2008, Proceedings of the National Academy of Sciences.
[25] A. Kulkarni,et al. A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells , 2008, Nature Immunology.
[26] J. Torres-Borrego,et al. Prevalence and associated factors of allergic rhinitis and atopic dermatitis in children. , 2008, Allergologia et immunopathologia.
[27] C. Benoist,et al. The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells , 2008, The Journal of experimental medicine.
[28] K. Furuuchi,et al. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer , 2008, Nature Immunology.
[29] Christophe Benoist,et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. , 2007, Immunity.
[30] Diego G. Silva,et al. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA , 2007, Nature.
[31] A. Rudensky,et al. TGFβ signalling in control of T-cell-mediated self-reactivity , 2007, Nature Reviews Immunology.
[32] T. Ludwig,et al. Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities. , 2007, Endocrinology.
[33] T. Chatila,et al. Regulatory T cell development in the absence of functional Foxp3 , 2007, Nature Immunology.
[34] M. Levings,et al. Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells. , 2007, Blood.
[35] Vincent C. Manganiello,et al. Foxp3-dependent programme of regulatory T-cell differentiation , 2007, Nature.
[36] Yonghong Xiao,et al. FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis , 2007, Cell.
[37] Wei He,et al. A FoxO–Smad synexpression group in human keratinocytes , 2006, Proceedings of the National Academy of Sciences.
[38] Shimon Sakaguchi,et al. Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. , 2006, International immunology.
[39] D. Sabatini,et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. , 2006, Molecular cell.
[40] S. Ziegler. FOXP3: of mice and men. , 2006, Annual review of immunology.
[41] A. Rudensky,et al. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires , 2006, Nature Immunology.
[42] Jack T. Lin,et al. TGF-β1 Uses Distinct Mechanisms to Inhibit IFN-γ Expression in CD4+ T Cells at Priming and at Recall: Differential Involvement of Stat4 and T-bet1 , 2005, The Journal of Immunology.
[43] R. Loewith,et al. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive , 2004, Nature Cell Biology.
[44] S. Hedrick,et al. The acquired immune system: a vantage from beneath. , 2004, Immunity.
[45] A. Singer,et al. IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1, and RORγt , 2004, The Journal of experimental medicine.
[46] M. Farrar,et al. Distinct IL-2 Receptor Signaling Pattern in CD4+CD25+ Regulatory T Cells1 , 2004, The Journal of Immunology.
[47] S. Anderson,et al. Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation , 2004, Cell.
[48] W. Biggs,et al. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[49] Li Li,et al. Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3 , 2003, The Journal of experimental medicine.
[50] G. Cooper,et al. The epidemiology of autoimmune diseases. , 2003, Autoimmunity reviews.
[51] A. Rudensky,et al. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells , 2003, Nature Immunology.
[52] S. Szabo,et al. The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease , 2002, The Journal of experimental medicine.
[53] René Hen,et al. Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease , 2000, Cell.
[54] M. Greenberg,et al. Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor , 1999, Cell.
[55] G. Kelsoe,et al. V(D)J recombinase activity in a subset of germinal center B lymphocytes. , 1997, Science.
[56] J. Bluestone,et al. Regulation of CTLA-4 expression during T cell activation. , 1996, Journal of immunology.
[57] J. Marth,et al. Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection. , 1995, Journal of immunology.
[58] F. Ramsdell,et al. gld/gld mice are unable to express a functional ligand for Fas , 1994, European journal of immunology.
[59] S. Hedrick,et al. In vivo and in vitro clonal deletion of double-positive thymocytes , 1992, The Journal of experimental medicine.
[60] E. Palmer,et al. An endogenous retrovirus mediating deletion of αβ T cells? , 1991, Nature.
[61] Ming O. Li,et al. Foxo: in command of T lymphocyte homeostasis and tolerance. , 2011, Trends in immunology.
[62] Fritz Melchers,et al. Checkpoints in lymphocyte development and autoimmune disease , 2010, Nature Immunology.
[63] Shimon Sakaguchi,et al. Regulatory T cells exert checks and balances on self tolerance and autoimmunity , 2010, Nature Immunology.
[64] W. Paul,et al. Heterogeneity and plasticity of T helper cells , 2010, Cell Research.
[65] D. Mueller. Mechanisms maintaining peripheral tolerance , 2010, Nature Immunology.
[66] A. Rudensky,et al. TGFbeta signalling in control of T-cell-mediated self-reactivity. , 2007, Nature reviews. Immunology.
[67] Naděžda Brdičková,et al. CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. , 2006, Nature.
[68] Jack T. Lin,et al. TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: differential involvement of Stat4 and T-bet. , 2005, Journal of immunology.
[69] E. Palmer,et al. An endogenous retrovirus mediating deletion of alpha beta T cells? , 1991, Nature.
[70] A. Singer,et al. IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1, and RORγt , 2004, The Journal of experimental medicine.