Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.
暂无分享,去创建一个
M. Reth | W. Schamel | Thomas Wossning | Alexandra Flemming | V. Rolli | Maike Gallwitz | Christa Zürn
[1] R. Aebersold,et al. The Direct Recruitment of BLNK to Immunoglobulin α Couples the B-Cell Antigen Receptor to Distal Signaling Pathways , 2002, Molecular and Cellular Biology.
[2] M. Rämet,et al. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli , 2002, Nature.
[3] J. Ferrell. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. , 2002, Current opinion in cell biology.
[4] T. Finkel,et al. Oxidants painting the cysteine chapel: redox regulation of PTPs. , 2002, Developmental cell.
[5] Toshiyuki Fukada,et al. Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. , 2002, Molecular cell.
[6] J. C. Barrett,et al. PART 1 : THE ROLE OF ROS IN HEALTH AND DISEASE OXIDANTS AND ANTIOXIDATIVE DEFENSE , 2002 .
[7] G. Superti-Furga,et al. Autoinhibition of c-Abl , 2002, Cell.
[8] K. Rajewsky,et al. Interference with Immunoglobulin (Ig)α Immunoreceptor Tyrosine–Based Activation Motif (Itam) Phosphorylation Modulates or Blocks B Cell Development, Depending on the Availability of an Igβ Cytoplasmic Tail , 2001, The Journal of experimental medicine.
[9] T. Finkel. Reactive Oxygen Species and Signal Transduction , 2001, IUBMB life.
[10] B. Wollscheid,et al. Association of SLP‐65 / BLNK with the B cell antigen receptor through a non‐ITAM tyrosine of Ig‐α , 2001, European journal of immunology.
[11] Shiaoching Gong,et al. B Cell Development Is Arrested at the Immature B Cell Stage in Mice Carrying a Mutation in the Cytoplasmic Domain of Immunoglobulin β , 2001, The Journal of experimental medicine.
[12] Y. Arimura,et al. Src Homology Region 2 (SH2) Domain-Containing Phosphatase-1 Dephosphorylates B Cell Linker Protein/SH2 Domain Leukocyte Protein of 65 kDa and Selectively Regulates c-Jun NH2-Terminal Kinase Activation in B Cells1 , 2000, The Journal of Immunology.
[13] M. Reth,et al. Monomeric and oligomeric complexes of the B cell antigen receptor. , 2000, Immunity.
[14] J. Cleveland,et al. Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors. , 2000, Immunity.
[15] T. Finkel. Redox‐dependent signal transduction , 2000, FEBS letters.
[16] J. D. Dal Porto,et al. Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction. , 2000, Current opinion in immunology.
[17] R. Bosotti,et al. Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding. , 2000, Biochemistry.
[18] Katsuhiko Hayashi,et al. The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[19] K. Lam,et al. B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice. , 2000, International immunology.
[20] T. Kurosaki,et al. BLNK: connecting Syk and Btk to calcium signals. , 2000, Immunity.
[21] R. Scheuermann,et al. Tyrosine kinase activation in the decision between growth, differentiation, and death responses initiated from the B cell antigen receptor. , 2000, Advances in immunology.
[22] A. Cheng,et al. Requirement for B cell linker protein (BLNK) in B cell development. , 1999, Science.
[23] D. Campana,et al. An essential role for BLNK in human B cell development. , 1999, Science.
[24] M. Reth,et al. Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65. , 1999, Immunity.
[25] M. Reth,et al. Interaction of SLP adaptors with the SH2 domain of Tec family kinases , 1999, European journal of immunology.
[26] T. Yamadori,et al. Identification of the SH2 domain binding protein of Bruton's tyrosine kinase as BLNK--functional significance of Btk-SH2 domain in B-cell antigen receptor-coupled calcium signaling. , 1999, Blood.
[27] R. Wagner,et al. High level expression of hepatitis B virus surface antigen in stably transfected Drosophila Schneider-2 cells. , 1999, Journal of virological methods.
[28] G. Waksman,et al. Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers. , 1999, Biochemistry.
[29] T. Kurosaki,et al. Genetic analysis of B cell antigen receptor signaling. , 1999, Annual review of immunology.
[30] M. Reth,et al. Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP‐65 and Syk , 1998, The EMBO journal.
[31] K. Uetsuka,et al. BASH, a novel signaling molecule preferentially expressed in B cells of the bursa of Fabricius. , 1998, Journal of immunology.
[32] R. Geahlen,et al. Syk- and Lyn-dependent phosphorylation of Syk on multiple tyrosines following B cell activation includes a site that negatively regulates signaling. , 1998, Journal of immunology.
[33] J. Cambier,et al. Antigen receptor signaling: integration of protein tyrosine kinase functions , 1998, Oncogene.
[34] G Waksman,et al. Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide. , 1998, Journal of molecular biology.
[35] Bernd Wollscheid,et al. SLP-65: A New Signaling Component in B Lymphocytes which Requires Expression of the Antigen Receptor for Phosphorylation , 1998, The Journal of experimental medicine.
[36] L. Mei,et al. Reversible regulation of SHP‐1 tyrosine phosphatase activity by oxidation , 1998, Biochemistry and molecular biology international.
[37] C. Turck,et al. BLNK: a central linker protein in B cell activation. , 1998, Immunity.
[38] A. George,et al. Expression of recombinant anti-E-selectin single-chain Fv antibody fragments in stably transfected insect cell lines. , 1998, Journal of immunological methods.
[39] D. Barford,et al. Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2. , 1998, Structure.
[40] T. Kurosaki. Molecular dissection of B cell antigen receptor signaling (review). , 1998, International journal of molecular medicine.
[41] C. Goodnow,et al. Positive versus negative signaling by lymphocyte antigen receptors. , 1998, Annual review of immunology.
[42] T. Pawson,et al. Signaling through scaffold, anchoring, and adaptor proteins. , 1997, Science.
[43] A. DeFranco,et al. The complexity of signaling pathways activated by the BCR. , 1997, Current opinion in immunology.
[44] D. Alexander,et al. The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction , 1997, BioEssays : news and reviews in molecular, cellular and developmental biology.
[45] R. Geahlen,et al. Syk Activation and Dissociation from the B-cell Antigen Receptor Is Mediated by Phosphorylation of Tyrosine 130* , 1997, The Journal of Biological Chemistry.
[46] M. Hibbs,et al. Lyn, a src-like tyrosine kinase. , 1997, The international journal of biochemistry & cell biology.
[47] M. Reth,et al. Evidence for a preformed transducer complex organized by the B cell antigen receptor. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[48] K. Rajewsky. Clonal selection and learning in the antibody system , 1996, Nature.
[49] M. Gold,et al. Reconstitution of B Cell Antigen Receptor-induced Signaling Events in a Nonlymphoid Cell Line by Expressing the Syk Protein-tyrosine Kinase (*) , 1996, The Journal of Biological Chemistry.
[50] M. Vihinen,et al. Structural aspects of signal transduction in B-cells. , 1996, Critical reviews in immunology.
[51] K. Sada,et al. Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling , 1995, The Journal of experimental medicine.
[52] J. Fargnoli,et al. Reconstitution of the B Cell Antigen Receptor Signaling Components in COS Cells (*) , 1995, The Journal of Biological Chemistry.
[53] J. Kinet,et al. Reconstitution of interactions between tyrosine kinases and the high affinity IgE receptor which are controlled by receptor clustering. , 1995, The EMBO journal.
[54] G. Mills,et al. Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling , 1995, The Journal of experimental medicine.
[55] J. Brugge,et al. Syk Is Activated by Phosphotyrosine-containing Peptides Representing the Tyrosine-based Activation Motifs of the High Affinity Receptor for IgE(*) , 1995, The Journal of Biological Chemistry.
[56] H. Wallny,et al. Soluble mouse major histocompatibility complex class II molecules produced in Drosophila cells , 1995, European journal of immunology.
[57] R. Rowley,et al. Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation , 1995, The Journal of Biological Chemistry.
[58] T. Kurosaki,et al. The structure and function of nonreceptor tyrosine kinase p72syk expressed in hematopoietic cells. , 1995, Cellular signalling.
[59] M. Reth,et al. The tyrosine activation motif as a target of protein tyrosine kinases and SH2 domains. , 1995, Seminars in immunology.
[60] J. Bolen,et al. Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI , 1995, Molecular and cellular biology.
[61] J. Cambier. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL) , 1995, Immunology today.
[62] J. Cyster,et al. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. , 1995, Immunity.
[63] L. Matsuuchi,et al. Structure and function of the B-cell antigen receptor. , 1994, Chemical immunology.
[64] T. Yamamoto,et al. Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling , 1994, The Journal of experimental medicine.
[65] A. Hata,et al. Tyrosine kinases Lyn and Syk regulate B cell receptor‐coupled Ca2+ mobilization through distinct pathways. , 1994, The EMBO journal.
[66] A. Weiss,et al. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. , 1994, Science.
[67] M. Reth,et al. Dual role of the tyrosine activation motif of the Ig‐alpha protein during signal transduction via the B cell antigen receptor. , 1994, The EMBO journal.
[68] M. Bertrand,et al. Recombinant protein expression in a Drosophila cell line: comparison with the baculovirus system , 1994 .
[69] R. Geahlen,et al. The role of Syk in cell signaling. , 1994, Advances in experimental medicine and biology.
[70] M. Nussenzweig,et al. Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta , 1993, The Journal of experimental medicine.
[71] M. Nussenzweig,et al. Functional reconstitution of an immunoglobulin antigen receptor in T cells , 1992, The Journal of experimental medicine.
[72] R. Kelly,et al. The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[73] M. Reth,et al. Molecular components of the B-cell antigen receptor complex of the IgM class , 1990, Nature.
[74] M. Reth. Antigen receptor tail clue , 1989, Nature.
[75] L. Goldstein,et al. Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. , 1988, Nucleic acids research.
[76] I. Schneider,et al. Cell lines derived from late embryonic stages of Drosophila melanogaster. , 1972, Journal of embryology and experimental morphology.