Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors

[1]  M. Nishimura,et al.  Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant , 2008, British Journal of Cancer.

[2]  M. Buendia,et al.  Physical and functional cooperation between AP-1 and β-catenin for the regulation of TCF-dependent genes , 2007, Oncogene.

[3]  Hans Clevers,et al.  Mining the Wnt pathway for cancer therapeutics , 2007, Nature Reviews Drug Discovery.

[4]  Axel Behrens,et al.  Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development , 2005, Nature.

[5]  H. McLeod,et al.  Differential expression of the AP-1 transcription factor family members in human colorectal epithelial and neuroendocrine neoplasms. , 2005, American journal of clinical pathology.

[6]  J. Sudbø,et al.  beta-catenin expression, DNA ploidy and clinicopathological features in ovarian cancer: a study in 253 patients. , 2005, European journal of cancer.

[7]  H. Donninger,et al.  Cyclin A Is a c-Jun Target Gene and Is Necessary for c-Jun-induced Anchorage-independent Growth in RAT1a Cells* , 2005, Journal of Biological Chemistry.

[8]  J. Kench,et al.  Lower levels of nuclear β‐catenin predict for a poorer prognosis in localized prostate cancer , 2005, International journal of cancer.

[9]  R. Nusse,et al.  Convergence of Wnt, ß-Catenin, and Cadherin Pathways , 2004, Science.

[10]  J. Chan,et al.  Prognostic and Diagnostic Significance of β-Catenin Nuclear Immunostaining in Colorectal Cancer , 2004, Clinical Cancer Research.

[11]  S. Roth,et al.  Mitogen-activated protein kinases and retinal ischemia. , 2003, Investigative ophthalmology & visual science.

[12]  S. C. Wong,et al.  Nuclear β catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong , 2003, Molecular pathology : MP.

[13]  E. Wagner,et al.  AP-1: a double-edged sword in tumorigenesis , 2003, Nature Reviews Cancer.

[14]  M. Birrer,et al.  AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets , 2003, Oncogene.

[15]  A. Sabichi,et al.  Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth , 2003, Oncogene.

[16]  Michael Karin,et al.  Oncogene at last--c-Jun promotes liver cancer in mice. , 2003, Cancer cell.

[17]  E. Wagner,et al.  Liver Tumor Development c-Jun Antagonizes the Proapoptotic Activity of p53 , 2003, Cell.

[18]  Y. Shiratori,et al.  Analysis of the β‐Catenin/T Cell Factor Signaling Pathway in 36 Gastrointestinal and Liver Cancer Cells , 2002, Japanese journal of cancer research : Gann.

[19]  K. Nozaki,et al.  Increased Expression of Phosphorylated c-Jun Amino-terminal Kinase and Phosphorylated c-Jun in Human Cerebral Aneurysms: Role of the c-Jun Amino-terminal Kinase/c-Jun Pathway in Apoptosis of Vascular Walls , 2002, Neurosurgery.

[20]  M. Pignatelli,et al.  β-catenin - A linchpin in colorectal carcinogenesis? , 2002 .

[21]  D. Rimm,et al.  Tissue Microarray Analysis of β-Catenin in Colorectal Cancer Shows Nuclear Phospho-β-catenin Is Associated with a Better Prognosis , 2001 .

[22]  Y. Atomi,et al.  Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas , 2001, British Journal of Cancer.

[23]  B. Fingleton,et al.  The PEA3 Subfamily of Ets Transcription Factors Synergizes with β-Catenin–LEF-1 To Activate Matrilysin Transcription in Intestinal Tumors , 2001, Molecular and Cellular Biology.

[24]  D. Chung,et al.  The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis. , 2000, Gastroenterology.

[25]  I. Ellis,et al.  Biological and clinical associations of c‐jun activation in human breast cancer , 2000, International journal of cancer.

[26]  E. Wagner,et al.  Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation , 1999, Nature Genetics.

[27]  L. Sobin,et al.  Colon and Rectum , 1998 .

[28]  K. Kinzler,et al.  Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma , 1997, Science.

[29]  K. Kinzler,et al.  Lessons from Hereditary Colorectal Cancer , 1996, Cell.

[30]  S. Steinberg,et al.  Altered cJUN expression: an early event in human lung carcinogenesis. , 1996, Cancer research.

[31]  M. Birrer,et al.  Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant. , 1994, Oncogene.

[32]  J. Woodgett,et al.  The stress-activated protein kinase subfamily of c-Jun kinases , 1994, Nature.

[33]  M. Karin,et al.  JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain , 1994, Cell.

[34]  J. Minna,et al.  Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[35]  J. R. Landis,et al.  The measurement of observer agreement for categorical data. , 1977, Biometrics.

[36]  R. Nusse,et al.  Convergence of Wnt, beta-catenin, and cadherin pathways. , 2004, Science.

[37]  H. Mizuguchi,et al.  Dominant-negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer , 2004, Gene Therapy.

[38]  J. Guillem,et al.  Matrix metalloproteinase-7 expression in colorectal cancer liver metastases: evidence for involvement of MMP-7 activation in human cancer metastases. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

[39]  M. Pignatelli,et al.  Beta-catenin--a linchpin in colorectal carcinogenesis? , 2002, The American journal of pathology.

[40]  D L Rimm,et al.  Tissue microarray analysis of beta-catenin in colorectal cancer shows nuclear phospho-beta-catenin is associated with a better prognosis. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[41]  Stanley R. Hamilton,et al.  Pathology and genetics of tumours of the digestive system , 2000 .

[42]  H Clevers,et al.  Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. , 1999, The American journal of pathology.

[43]  F. McCormick,et al.  Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. , 1999, Nature.

[44]  M. Monden,et al.  Beta-catenin expression in human cancers. , 1996, The American journal of pathology.