Fluidised-Bed Granulation: A Chronology

AbstractThis paper is a chronological survey of published work in the field of pharmaceutical fluidised-bed granulation. It begins with early experiments in the 1960s and continues to include all relevant published work up to 1990. To aid the reader find published material for further in-depth reading a cross reference to published articles on a subject basis is provided in tabular form.

[1]  Gert Ragnarsson,et al.  Influence of the granulating method on bulk properties and tablettability of a high dosage drug , 1982 .

[2]  M. Aulton,et al.  THE WETTABILITY OF POWDERS DURING FLUIDIZED BED GRANULATION , 1977, The Journal of pharmacy and pharmacology.

[3]  H. Lieberman,et al.  CONTINUOUS PRODUCTION OF TABLET GRANULATIONS IN A FLUIDIZED BED. II. OPERATION AND PERFORMANCE OF EQUIPMENT. , 1964, Journal of pharmaceutical sciences.

[4]  M. J. Crooks,et al.  Fluidized bed granulation of a microdose pharmaceutical powder , 1978 .

[5]  K.-F. Jäger,et al.  Verwendung von Polymerblends aus Polyvinylpyrrolidonen zur Optimierung der Eigenschaften von Aufbaugranulaten und Tabletten , 1984 .

[6]  Alvin W. Nienow,et al.  Particle growth mechanisms in fluidised bed granulation—I: The effect of process variables , 1983 .

[7]  M. E. Aulton,et al.  A Fluorescent Technique for the Observation of Polyvinylpyrrolidone Binder Distribution in Granules , 1978 .

[8]  B. Csukás,et al.  Studies On Granulation in a Fluidized Bed II. The Effects of the Amount of the Binder on the Physical Properties of Granules Formed in a Fluidized Bed , 1973 .

[9]  A. W. Nienow,et al.  Fluidized bed granulation technology and its application to tungsten carbide , 1986 .

[10]  D. Wurster,et al.  Air-suspension technique of coating drug particles; a preliminary report. , 1959, Journal of the American Pharmaceutical Association. American Pharmaceutical Association.

[11]  Derek Wilkinson,et al.  Kinetics and mechanisms of growth in batch and continuous fluidized bed granulation , 1987 .

[12]  D. Wurster,et al.  Preparation of compressed tablet granulations by the air-suspension technique. II. , 1960, Journal of the American Pharmaceutical Association. American Pharmaceutical Association.

[13]  W L Davies,et al.  Batch production of pharmaceutical granulations in a fluidized bed. II. Effects of various binders and their concentrations on granulations and compressed tablets. , 1972, Journal of pharmaceutical sciences.

[14]  Torben Schæfer,et al.  Granulation: A Review on Pharmaceutical Wet-Granulation , 1987 .

[15]  W A Ritschel,et al.  Bioavailability of sulfadiazine in rabbits using tablets prepared by direct compression and fluidized-bed granulation. , 1977, Journal of pharmaceutical sciences.

[16]  J T Carstensen,et al.  Influence of granulation liquid flow rate on particle-size distribution in spray-granulate products. , 1977, Journal of pharmaceutical sciences.

[17]  Kazuo Harada.  Particle Growth of Simultaneous Coating and Agglomeration in the Fluidized Bed , 1972 .

[18]  M. Alkan,et al.  Granulation in a Fluidized Bed II Effect of Binder Amount on the Final Granules , 1986 .

[19]  A S RANKELL,et al.  CONTINUOUS PRODUCTION OF TABLET GRANULATIONS IN A FLUIDIZED BED. I. THEORY AND DESIGN CONSIDERATIONS. , 1964, Journal of pharmaceutical sciences.

[20]  W L Davies,et al.  Batch production of pharmaceutical granulations in a fluidized bed. I. Effects of process variables on physical properties of final granulation. , 1971, Journal of pharmaceutical sciences.

[21]  A. Nouh,et al.  The effect of variations in concentration and type of binder on the physical characteristics of sulfadiazine tablets and granulations prepared by wet and fluidised-bed granulation method , 1986 .

[22]  W L Davies,et al.  Batch production of pharmaceutical granulations in a fluidized bed. 3. Binder dilution effects on granulation. , 1973, Journal of pharmaceutical sciences.

[23]  Zoltan Ormos,et al.  Studies on Granulation in a Fluidized Bed IV. Effects of the Characteristic of the Fluidized Bed the Atomization and the Air Distributor Upon the Physical Properties of the Granulates , 1973 .

[24]  A Dévay,et al.  Optimization of operational parameters in fluidized bed granulation of effervescent pharmaceutical preparations , 1984 .

[25]  H. O. Kono,et al.  A mathematical coalescence model in the batch fluidized bed granulator , 1988 .

[26]  F. Higashide,et al.  Dependence of drug content uniformity on particle sizes in fluidized bed granulation , 1985 .

[27]  D Campy,et al.  Scale up considerations in fluidized bed granulation: Air flow rates and air pressure distribution , 1974, The Journal of pharmacy and pharmacology.

[28]  F. A. Hoffmann,et al.  Untersuchungen über das Verhalten des Jendrassik’schen Bahnungseffektes auf spinale Eigenreflexe unter neuroleptischer Medikation , 1960 .

[29]  A. W. Nienow,et al.  Particle growth mechanisms in fluidised bed granulation—II: Comparison of experimental data with growth models , 1983 .

[30]  Zoltan Ormos,et al.  Studies on Granulation in a Fluidized Bed III. Calculation of the Feed Rate of Granulating Liquid , 1973 .

[31]  M. Aulton,et al.  THE MEASUREMENT OF SPRAY DROPLET SIZE DISTRIBUTIONS , 1979 .

[32]  W J Thiel,et al.  Fluidized bed granulation of an ordered powder mixture , 1982, The Journal of pharmacy and pharmacology.