Clinical Approach of T1‐mapping for Hemodynamic Analysis

Our current study concerns T1 measurement and mapping for dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in clinical settings. The methodology requires rapid, accurate, and reproducible measurements in order to calculate various pharmacokinetic kinetic parameters. We are focusing on methodology, application, and future development of T1 mapping for DCE-MRI. The current study explains the methodology of three T1 measurement methods; variable flip angle(VFA), variable reputation time(VTR), and Look-Locker(LL), respectively. Moreover, for future studies, we discuss the possibility of compressed sensing(CS)and MR fingerprinting(MRF)on T1 mapping. The physical methodology of T1 mapping for hemodynamic analysis will become more and more important in clinical and practical settings.

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