Resolution of overlapping spectra by curve-fitting

Abstract In this paper we present a novel method of curve-fitting based on Gaussian function, which is used to resolve the overlapping peaks. Correctly choosing the minimum separable peak–peak interval (MSI) is crucial for this type of problem. We propose a method that chooses appropriate MSI by analyzing the curve-fitting error changes with the MSI. The resolution of several kinds of overlapping peaks with computer-simulated noise has been performed and discussed in details. This method has been used for resolving of the UV–vis overlapping spectrum. The results are satisfactory and clearly show the effectiveness of the proposed method.